6HWF: Yeast 20S proteasome beta2-G45A mutant in complex with ONX 0914

PDB ID: 6HWFDownload
MMDB ID: 171840
PDB Deposition Date: 2018/10/11
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6HWF: 28-meric; determined by author
Molecular Components in 6HWF
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type-2
(Gene symbol: PRE8)
Molecule annotation
2
Proteasome Subunit Alpha Type-3
(Gene symbol: PRE9)
Molecule annotation
2
Proteasome Subunit Alpha Type-4
(Gene symbol: PRE6)
Molecule annotation
2
Proteasome Subunit Alpha Type-5
(Gene symbol: PUP2)
Molecule annotation
2
Proteasome Subunit Alpha Type-6
(Gene symbol: PRE5)
Molecule annotation
2
Probable Proteasome Subunit Alpha Type-7
(Gene symbol: PRE10)
Molecule annotation
2
Proteasome Subunit Alpha Type-1
(Gene symbol: SCL1)
Molecule annotation
2
Proteasome Subunit Beta Type-2
(Gene symbol: PUP1)
Molecule annotation
2
Proteasome Subunit Beta Type-3
(Gene symbol: PUP3)
Molecule annotation
2
Proteasome Subunit Beta Type-4
(Gene symbol: PRE1)
Molecule annotation
2
Proteasome Subunit Beta Type-5
(Gene symbol: PRE2)
Molecule annotation
2
Proteasome Subunit Beta Type-6
(Gene symbol: PRE7)
Molecule annotation
2
Proteasome Subunit Beta Type-7
(Gene symbol: PRE4)
Molecule annotation
2
Proteasome Subunit Beta Type-1
(Gene symbol: PRE3)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
8
MAGNESIUM IONMAGNESIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
6
(2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{R})-4-methyl-3,4-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide(2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{R})-4-methyl-3,4-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide
4
4
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
5
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303