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PRE10 proteasome core particle subunit alpha 7 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854544, updated on 10-Mar-2023

Summary

Gene symbol
PRE10
Gene description
proteasome core particle subunit alpha 7
Primary source
SGD:S000005889
Locus tag
YOR362C
See related
AllianceGenome:SGD:S000005889
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables mRNA binding activity. Involved in proteasomal ubiquitin-independent protein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in proteasome storage granule. Part of proteasome core complex, alpha-subunit complex. Orthologous to human PSMA3 (proteasome 20S subunit alpha 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See PRE10 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (1017880..1018746, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene 3',5'-cyclic-nucleotide phosphodiesterase PDE2 Neighboring gene translation initiation factor eIF3 core subunit b Neighboring gene oleate-activated transcription factor PIP2 Neighboring gene putative flavin adenine dinucleotide transporter

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the PRE10 gene: The PRE10 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IC
Inferred by Curator
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear outer membrane-endoplasmic reticulum membrane network IC
Inferred by Curator
more info
PubMed 
located_in nuclear outer membrane-endoplasmic reticulum membrane network IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome core complex IEA
Inferred from Electronic Annotation
more info
 
part_of proteasome core complex, alpha-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of proteasome core complex, alpha-subunit complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of proteasome core complex, alpha-subunit complex IEA
Inferred from Electronic Annotation
more info
 
located_in proteasome storage granule IDA
Inferred from Direct Assay
more info
PubMed 
located_in proteasome storage granule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
proteasome core particle subunit alpha 7
NP_015007.1
  • Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    1017880..1018746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183782.1NP_015007.1  TPA: proteasome core particle subunit alpha 7 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015007.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W357, P21242
    UniProtKB/TrEMBL
    A0A0L8VGR4, A0A6A5Q4M4, A0A6C1E0M9, A6ZPJ2, B3LK19, C7GNQ6, C8ZHB0, G2WNM3, H0GP49, N1NXJ2
    Conserved Domains (1) summary
    cd03751
    Location:5219
    proteasome_alpha_type_3; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...