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The Genome Reference Consortium

Putting sequences into a chromosome context.

The original model for representing the genome assemblies was to use a single, preferred tiling path to produce a single consensus representation of the genome. Subsequent analysis has shown that for most mammalian genomes a single tiling path is insufficient to represent a genome in regions with complex allelic diversity. The GRC is now working to create assemblies that better represent this diversity and provide more robust substrates for genome analysis.

The GRC announces the release of GRCz11. This is a major, coordinate changing, assembly release. The GRC website will soon be updated with the new assembly metrics.The assembly files can be retrieved from the GenBank FTP site.

Transitioning to GRCh38 or GRCz11? Try the NCBI Remapping Service, which uses the same assembly-assembly alignments used by the GRC.

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