Nov 30, 2020
Jul 22, 2020see all
Information about the continuing improvement of the mouse genome
The GRC is working hard to provide the best possible reference assembly for mouse. In the mouse reference assembly, sequences in the primary assembly unit (chromosomes and unlocalized and unplaced scaffolds) come from the C57BL/6J strain. For several genomic regions that are variable between different strains, we provide alternate loci scaffolds comprised of clone-based sequences from a variety of other strains. Additionally, we are releasing regional fixes known as patches. This allows users who are interested in a specific locus to get an improved representation without affecting users who need chromosome coordinate stability.
Ideogram of the latest mouse assembly, GRCm39
Jul 22, 2020MG-4409
Review confirms the over-expansion, and AC175032.1, AC174723.2 and AC174479.2 have been removed from the assembly.
Jul 2, 2020MG-4414
The mouse chr Y centromere, described in PubMed record 25417157, was included in GRCm38. It is a 90kb sub-region of component AC175459.3 (57238..147035). This corresponds to CM001014.2/NC_000087.7: 4072168-4161965.