Nov 08, 2016
Oct 24, 2016see all
Information about the continuing improvement of the zebrafish genome
After the release of Zv9 in July 2010, the GRC has taken over the improvement and maintenance of the zebrafish genome assembly. In the four years since, the GRC has been working on filling gaps with new clone sequence and improving the positioning of assembly components with the help of optical mapping, Strandseq (M. Hills, PMID: 24028793) and additional meiotic mapping (GAPmap, D. Stemple, unpublished). The resulting improved clone path was supplemented with a new whole genome shotgun assembly WGS31, based on a combination of Illumina and capillary reads from double-haploid Tuebingen individuals, leading to the release of the integrated zebrafish genome assembly GRCz10.
Ideogram of the latest zebrafish assembly, GRCz10