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ZNF765 zinc finger protein 765 [ Homo sapiens (human) ]

Gene ID: 91661, updated on 8-Dec-2022

Summary

Official Symbol
ZNF765provided by HGNC
Official Full Name
zinc finger protein 765provided by HGNC
Primary source
HGNC:HGNC:25092
See related
Ensembl:ENSG00000196417 AllianceGenome:HGNC:25092
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 4.5), testis (RPKM 2.5) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF765 in Genome Data Viewer
Location:
19q13.42
Exon count:
9
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (53395149..53427321)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (56474647..56506876)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53898402..53930574)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 845 Neighboring gene putative zinc finger protein 137 Neighboring gene zinc finger protein 525 Neighboring gene ribosomal protein L39 pseudogene 35 Neighboring gene ZNF765-ZNF761 readthrough Neighboring gene putative zinc finger protein 137 Neighboring gene ribosomal protein L39 pseudogene 36 Neighboring gene vomeronasal 1 receptor 101 pseudogene Neighboring gene tropomyosin 3 pseudogene 9 Neighboring gene zinc finger protein 761 Neighboring gene vomeronasal 1 receptor 102 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough ZNF765-ZNF761

Readthrough gene: ZNF765-ZNF761, Included gene: ZNF525, Included gene: ZNF761

Homology

Clone Names

  • FLJ30902, DKFZp686J2252

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040185.3NP_001035275.1  zinc finger protein 765 isoform 1

    See identical proteins and their annotated locations for NP_001035275.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC022137, CD656338
    Consensus CDS
    CCDS46171.1
    UniProtKB/Swiss-Prot
    Q7L2R6, Q9BV49
    Related
    ENSP00000379689.3, ENST00000396408.8
    Conserved Domains (5) summary
    smart00349
    Location:848
    KRAB; krueppel associated box
    COG5048
    Location:325477
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:329349
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:314338
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001350495.2NP_001337424.1  zinc finger protein 765 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022137
    Conserved Domains (3) summary
    COG5048
    Location:272424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:276296
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:204229
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_146721.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC022137, BC017357
    Related
    ENST00000504235.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    53395149..53427321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    56474647..56506876
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)