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ZNF333 zinc finger protein 333 [ Homo sapiens (human) ]

Gene ID: 84449, updated on 1-Jun-2020

Summary

Official Symbol
ZNF333provided by HGNC
Official Full Name
zinc finger protein 333provided by HGNC
Primary source
HGNC:HGNC:15624
See related
Ensembl:ENSG00000160961 MIM:611811
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in appendix (RPKM 2.4), endometrium (RPKM 2.3) and 25 other tissues See more
Orthologs

Genomic context

See ZNF333 in Genome Data Viewer
Location:
19p13.12
Exon count:
19
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (14689787..14733742)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (14800711..14844558)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor E3 Neighboring gene small nucleolar RNA, H/ACA box 104 Neighboring gene integrin subunit beta 1 pseudogene 1 Neighboring gene uncharacterized LOC107985308 Neighboring gene adhesion G protein-coupled receptor E2 Neighboring gene CRISPRi-validated cis-regulatory element chr19.2424 Neighboring gene transmembrane protein 167A pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
capsid gag The interaction of HIV-1 CA with human cellular zinc finger protein 333 (ZNF333) is identified by yeast two-hybrid screen PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1806

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001300912.2NP_001287841.1  zinc finger protein 333 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate 3' terminal exon, resulting in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC090427, AF372702, BC048107, DA103403
    Consensus CDS
    CCDS74298.1
    UniProtKB/Swiss-Prot
    Q96JL9
    Related
    ENSP00000438130.1, ENST00000540689.6
    Conserved Domains (2) summary
    smart00349
    Location:203263
    KRAB; krueppel associated box
    pfam01352
    Location:203242
    KRAB; KRAB box
  2. NM_001352239.2NP_001339168.1  zinc finger protein 333 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC090427, AF372702, BP231733, DA103403, HY032449
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  3. NM_001352240.2NP_001339169.1  zinc finger protein 333 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC090427, AF372702, BP231733, DA103403, DC335178, HY032449
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  4. NM_001352241.2NP_001339170.1  zinc finger protein 333 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC090427, AF372702, DA103403, DA248936
    Conserved Domains (4) summary
    smart00349
    Location:57117
    KRAB; krueppel associated box
    COG5048
    Location:211379
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:278298
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:403426
    zf-H2C2_2; Zinc-finger double domain
  5. NM_001352243.2NP_001339172.1  zinc finger protein 333 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC090427, AF372702, DA103403
    Conserved Domains (4) summary
    COG5048
    Location:126294
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:193213
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:318341
    zf-H2C2_2; Zinc-finger double domain
    cl02581
    Location:132
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  6. NM_001352244.2NP_001339173.1  zinc finger protein 333 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC090427, AF372702, DA103403
    Conserved Domains (1) summary
    smart00349
    Location:203263
    KRAB; krueppel associated box
  7. NM_032433.4NP_115809.1  zinc finger protein 333 isoform 1

    See identical proteins and their annotated locations for NP_115809.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC090427, AF372702, DA103403
    Consensus CDS
    CCDS12316.1
    UniProtKB/Swiss-Prot
    Q96JL9
    Related
    ENSP00000292530.5, ENST00000292530.11
    Conserved Domains (6) summary
    smart00349
    Location:203263
    KRAB; krueppel associated box
    COG5048
    Location:228525
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:424444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:394416
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:203242
    KRAB; KRAB box
    pfam13465
    Location:408433
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    14689787..14733742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011528362.2XP_011526664.1  zinc finger protein 333 isoform X1

    See identical proteins and their annotated locations for XP_011526664.1

    UniProtKB/Swiss-Prot
    Q96JL9
    Conserved Domains (6) summary
    smart00349
    Location:203263
    KRAB; krueppel associated box
    COG5048
    Location:228525
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:424444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:394416
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:203242
    KRAB; KRAB box
    pfam13465
    Location:408433
    zf-H2C2_2; Zinc-finger double domain
  2. XM_011528369.2XP_011526671.1  zinc finger protein 333 isoform X2

    See identical proteins and their annotated locations for XP_011526671.1

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  3. XM_011528368.2XP_011526670.1  zinc finger protein 333 isoform X2

    See identical proteins and their annotated locations for XP_011526670.1

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  4. XM_024451741.1XP_024307509.1  zinc finger protein 333 isoform X3

    Conserved Domains (4) summary
    smart00349
    Location:57117
    KRAB; krueppel associated box
    COG5048
    Location:211379
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:278298
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:403426
    zf-H2C2_2; Zinc-finger double domain
  5. XM_011528367.2XP_011526669.1  zinc finger protein 333 isoform X2

    See identical proteins and their annotated locations for XP_011526669.1

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  6. XM_017027370.1XP_016882859.1  zinc finger protein 333 isoform X2

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  7. XM_024451740.1XP_024307508.1  zinc finger protein 333 isoform X3

    Conserved Domains (4) summary
    smart00349
    Location:57117
    KRAB; krueppel associated box
    COG5048
    Location:211379
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:278298
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:403426
    zf-H2C2_2; Zinc-finger double domain
  8. XM_017027369.1XP_016882858.1  zinc finger protein 333 isoform X2

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  9. XM_011528363.2XP_011526665.1  zinc finger protein 333 isoform X2

    See identical proteins and their annotated locations for XP_011526665.1

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  10. XM_011528365.2XP_011526667.1  zinc finger protein 333 isoform X2

    See identical proteins and their annotated locations for XP_011526667.1

    UniProtKB/TrEMBL
    B3KSN8
    Conserved Domains (5) summary
    smart00349
    Location:94154
    KRAB; krueppel associated box
    COG5048
    Location:119416
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:315335
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:509531
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:440463
    zf-H2C2_2; Zinc-finger double domain
  11. XM_017027367.1XP_016882856.1  zinc finger protein 333 isoform X1

    UniProtKB/Swiss-Prot
    Q96JL9
    Conserved Domains (6) summary
    smart00349
    Location:203263
    KRAB; krueppel associated box
    COG5048
    Location:228525
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:424444
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:394416
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:203242
    KRAB; KRAB box
    pfam13465
    Location:408433
    zf-H2C2_2; Zinc-finger double domain
  12. XM_011528371.2XP_011526673.1  zinc finger protein 333 isoform X4

    Conserved Domains (6) summary
    smart00349
    Location:1474
    KRAB; krueppel associated box
    COG5048
    Location:168336
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:235255
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:205227
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1453
    KRAB; KRAB box
    pfam13465
    Location:219244
    zf-H2C2_2; Zinc-finger double domain
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