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ZNF212 zinc finger protein 212 [ Homo sapiens (human) ]

Gene ID: 7988, updated on 5-Nov-2017
Official Symbol
ZNF212provided by HGNC
Official Full Name
zinc finger protein 212provided by HGNC
Primary source
HGNC:HGNC:13004
See related
Ensembl:ENSG00000170260 MIM:602386; Vega:OTTHUMG00000158968
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF182; ZNFC150; C2H2-150
Summary
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in testis (RPKM 6.4), endometrium (RPKM 4.5) and 25 other tissues See more
Orthologs
Location:
7q36.1
Exon count:
6
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 7 NC_000007.14 (149239648..149255609)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (148936741..148952700)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene zinc finger protein 398 Neighboring gene centrosomal protein 83kDa pseudogene Neighboring gene zinc finger protein 282 Neighboring gene zinc finger family member 783 Neighboring gene AI894139 pseudogene

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016
  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC9707

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated NAS
Non-traceable Author Statement
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
 
Preferred Names
zinc finger protein 212
Names
Zinc finger protein C2H2-150

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012256.3NP_036388.2  zinc finger protein 212

    See identical proteins and their annotated locations for NP_036388.2

    Status: REVIEWED

    Source sequence(s)
    AI242662, AK074821, BC022785
    Consensus CDS
    CCDS5896.1
    UniProtKB/Swiss-Prot
    Q9UDV6
    UniProtKB/TrEMBL
    A0A090N8N3, B3KQE6
    Related
    ENSP00000338572.2, OTTHUMP00000213752, ENST00000335870.6, OTTHUMT00000352710
    Conserved Domains (6) summary
    cd07765
    Location:142180
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:367479
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:318338
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:429449
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:441466
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p7 Primary Assembly

    Range
    149239648..149255609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005250055.2XP_005250112.2  zinc finger protein 212 isoform X1

    Conserved Domains (6) summary
    cd07765
    Location:182220
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:459517
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:411431
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:358378
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:469489
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:481506
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017012646.1XP_016868135.1  zinc finger protein 212 isoform X2

  3. XM_011516581.2XP_011514883.2  zinc finger protein 212 isoform X5

  4. XM_017012648.1XP_016868137.1  zinc finger protein 212 isoform X4

    Conserved Domains (6) summary
    cd07765
    Location:88126
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:365423
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:317337
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:264284
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:375395
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:387412
    zf-H2C2_2; Zinc-finger double domain
  5. XM_017012647.1XP_016868136.1  zinc finger protein 212 isoform X3

  6. XM_011516582.1XP_011514884.1  zinc finger protein 212 isoform X4

    Conserved Domains (6) summary
    cd07765
    Location:88126
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    COG5048
    Location:365423
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:317337
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:264284
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:375395
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:387412
    zf-H2C2_2; Zinc-finger double domain

Alternate CHM1_1.1

Genomic

  1. NC_018918.2 Alternate CHM1_1.1

    Range
    148945125..148961093
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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