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ZNF667 zinc finger protein 667 [ Homo sapiens (human) ]

Gene ID: 63934, updated on 5-Sep-2021

Summary

Official Symbol
ZNF667provided by HGNC
Official Full Name
zinc finger protein 667provided by HGNC
Primary source
HGNC:HGNC:28854
See related
Ensembl:ENSG00000198046 MIM:611024
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIPU1
Expression
Broad expression in brain (RPKM 3.0), thyroid (RPKM 2.8) and 22 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See ZNF667 in Genome Data Viewer
Location:
19q13.43
Exon count:
14
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (56438512..56478065, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56950698..56988714, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ZNF582 divergent transcript Neighboring gene zinc finger protein 583 Neighboring gene ZNF667 antisense RNA 1 (head to head) Neighboring gene uncharacterized LOC105372471 Neighboring gene zinc finger protein 471

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14011, FLJ45518, DKFZp686O111

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 667
Names
myocardial ischemic preconditioning upregulated 1 ortholog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001321355.2NP_001308284.1  zinc finger protein 667 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC013256, AC098795
    UniProtKB/TrEMBL
    Q5CZB4
    Conserved Domains (3) summary
    COG5048
    Location:84544
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:444464
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:456481
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001321356.2NP_001308285.1  zinc finger protein 667 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC006116, AC013256, AC098795
    Consensus CDS
    CCDS12944.1
    UniProtKB/Swiss-Prot
    Q5HYK9
    Related
    ENSP00000439402.1, ENST00000504904.8
    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_022103.4NP_071386.3  zinc finger protein 667 isoform 1

    See identical proteins and their annotated locations for NP_071386.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the functional protein.
    Source sequence(s)
    AC006116, AC013256, AC098795
    Consensus CDS
    CCDS12944.1
    UniProtKB/Swiss-Prot
    Q5HYK9
    Related
    ENSP00000292069.5, ENST00000292069.10
    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    56438512..56478065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024451637.1XP_024307405.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_024451642.1XP_024307410.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_024451646.1XP_024307414.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_024451647.1XP_024307415.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_024451645.1XP_024307413.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011527208.2XP_011525510.1  zinc finger protein 667 isoform X1

    See identical proteins and their annotated locations for XP_011525510.1

    UniProtKB/Swiss-Prot
    Q5HYK9
    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_024451643.1XP_024307411.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_024451644.1XP_024307412.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  9. XM_024451641.1XP_024307409.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  10. XM_024451640.1XP_024307408.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  11. XM_024451639.1XP_024307407.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
  12. XM_024451638.1XP_024307406.1  zinc finger protein 667 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:1574
    KRAB; krueppel associated box
    COG5048
    Location:141601
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:501521
    ZF_C2H2; C2H2 Zn finger [structural motif]
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