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KIF1A kinesin family member 1A [ Homo sapiens (human) ]

Gene ID: 547, updated on 25-Nov-2021

Summary

Official Symbol
KIF1Aprovided by HGNC
Official Full Name
kinesin family member 1Aprovided by HGNC
Primary source
HGNC:HGNC:888
See related
Ensembl:ENSG00000130294 MIM:601255
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATSV; MRD9; HSN2C; SPG30; UNC104; C2orf20; NESCAVS
Summary
The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Expression
Biased expression in brain (RPKM 88.6), adrenal (RPKM 8.2) and 1 other tissue See more
Orthologs
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Genomic context

See KIF1A in Genome Data Viewer
Location:
2q37.3
Exon count:
55
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (240713767..240821403, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (241653184..241760820, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC285191 Neighboring gene aquaporin 12A Neighboring gene alanine--glyoxylate and serine--pyruvate aminotransferase Neighboring gene mab-21 like 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
capsid gag The ability of exogenously expressed FEZ1 binding to kinesin-1 to promote early HIV-1 infection, leading to the movement of HIV-1 CA core to the nucleus PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ30229, MGC133285, MGC133286, DKFZp686I2094

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytoskeletal motor activity TAS
Traceable Author Statement
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables plus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in anterograde axonal transport TAS
Traceable Author Statement
more info
PubMed 
involved_in anterograde neuronal dense core vesicle transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cytoskeleton-dependent intracellular transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dense core granule cytoskeletal transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of dendritic spine development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of dendritic spine morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in retrograde neuronal dense core vesicle transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extrinsic component of neuronal dense core vesicle membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of kinesin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuronal dense core vesicle ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
kinesin-like protein KIF1A
Names
axonal transporter of synaptic vesicles
kinesin, heavy chain, member 1A, homolog of mouse
microtubule-based motor KIF1A
unc-104- and KIF1A-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029724.1 RefSeqGene

    Range
    4900..111444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_367

mRNA and Protein(s)

  1. NM_001244008.2NP_001230937.1  kinesin-like protein KIF1A isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Consensus CDS
    CCDS58757.1
    UniProtKB/Swiss-Prot
    Q12756
    Related
    ENSP00000438388.1, ENST00000498729.9
    Conserved Domains (8) summary
    smart00129
    Location:5361
    KISc; Kinesin motor, catalytic domain. ATPase
    cd00060
    Location:501605
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16721774
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam00169
    Location:16771770
    PH; PH domain
    pfam12423
    Location:814861
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12971397
    DUF3694; Kinesin protein
    pfam16183
    Location:358524
    Kinesin_assoc; Kinesin-associated
  2. NM_001320705.2NP_001307634.1  kinesin-like protein KIF1A isoform 3

    Status: REVIEWED

    Source sequence(s)
    AB210029, AB290172, AC011298, AW246876, BC111780
    UniProtKB/Swiss-Prot
    Q12756
    Related
    ENSP00000498196.1, ENST00000648364.1
    Conserved Domains (8) summary
    smart00129
    Location:5361
    KISc; Kinesin motor, catalytic domain. ATPase
    cd00060
    Location:501605
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15801682
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam00169
    Location:15851678
    PH; PH domain
    pfam12423
    Location:814860
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12051305
    DUF3694; Kinesin protein
    pfam16183
    Location:358524
    Kinesin_assoc; Kinesin-associated
  3. NM_001330289.2NP_001317218.1  kinesin-like protein KIF1A isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784, AK054791, AW246876
    Related
    ENSP00000497586.1, ENST00000648680.1
    Conserved Domains (8) summary
    smart00129
    Location:5361
    KISc; Kinesin motor, catalytic domain. ATPase
    cd00060
    Location:501605
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15891691
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam00169
    Location:15941687
    PH; PH domain
    pfam12423
    Location:814860
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12051314
    DUF3694; Kinesin protein
    pfam16183
    Location:358524
    Kinesin_assoc; Kinesin-associated
  4. NM_001330290.2NP_001317219.1  kinesin-like protein KIF1A isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784, AK054791, AW246876
    Related
    ENSP00000497678.1, ENST00000649306.1
  5. NM_001379631.1NP_001366560.1  kinesin-like protein KIF1A isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
  6. NM_001379632.1NP_001366561.1  kinesin-like protein KIF1A isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16641766
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805852
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12331389
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  7. NM_001379633.1NP_001366562.1  kinesin-like protein KIF1A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000497293.1, ENST00000648129.1
  8. NM_001379634.1NP_001366563.1  kinesin-like protein KIF1A isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
  9. NM_001379635.1NP_001366564.1  kinesin-like protein KIF1A isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:526630
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16131715
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:839885
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11831338
    DUF3694; Kinesin protein
    pfam16183
    Location:358549
    Kinesin_assoc; Kinesin-associated
  10. NM_001379636.1NP_001366565.1  kinesin-like protein KIF1A isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000497739.1, ENST00000647885.1
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16091711
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491334
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  11. NM_001379637.1NP_001366566.1  kinesin-like protein KIF1A isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:517621
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15961698
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:830876
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11741321
    DUF3694; Kinesin protein
    pfam16183
    Location:358540
    Kinesin_assoc; Kinesin-associated
  12. NM_001379638.1NP_001366567.1  kinesin-like protein KIF1A isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:501605
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15881690
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:814860
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11581313
    DUF3694; Kinesin protein
    pfam16183
    Location:358524
    Kinesin_assoc; Kinesin-associated
  13. NM_001379639.1NP_001366568.1  kinesin-like protein KIF1A isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000322791.8, ENST00000320389.12
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15791681
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491304
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  14. NM_001379640.1NP_001366569.1  kinesin-like protein KIF1A isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15701672
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11481295
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  15. NM_001379641.1NP_001366570.1  kinesin-like protein KIF1A isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15711661
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491296
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  16. NM_001379642.1NP_001366571.1  kinesin-like protein KIF1A isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16721774
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805852
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:12411397
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  17. NM_001379645.1NP_001366574.1  kinesin-like protein KIF1A isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000498082.1, ENST00000650130.1
  18. NM_001379646.1NP_001366575.1  kinesin-like protein KIF1A isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000497935.1, ENST00000648047.1
    Conserved Domains (6) summary
    cd00060
    Location:526630
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16131715
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:839885
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11831338
    DUF3694; Kinesin protein
    pfam16183
    Location:358549
    Kinesin_assoc; Kinesin-associated
  19. NM_001379648.1NP_001366577.1  kinesin-like protein KIF1A isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (3) summary
    cd00060
    Location:517621
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:16051707
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
  20. NM_001379649.1NP_001366578.1  kinesin-like protein KIF1A isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000498099.1, ENST00000647731.1
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15801682
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491305
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  21. NM_001379650.1NP_001366579.1  kinesin-like protein KIF1A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Related
    ENSP00000497824.1, ENST00000650053.1
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15711673
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491296
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  22. NM_001379651.1NP_001366580.1  kinesin-like protein KIF1A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15711673
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491296
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  23. NM_001379653.1NP_001366582.1  kinesin-like protein KIF1A isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15711673
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491296
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated
  24. NM_004321.8NP_004312.2  kinesin-like protein KIF1A isoform 2

    See identical proteins and their annotated locations for NP_004312.2

    Status: REVIEWED

    Source sequence(s)
    AC011298, AC112784
    Consensus CDS
    CCDS46561.1
    UniProtKB/Swiss-Prot
    Q12756
    Related
    ENSP00000497030.1, ENST00000649096.1
    Conserved Domains (6) summary
    cd00060
    Location:492596
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd01233
    Location:15711673
    PH_KIFIA_KIFIB; KIFIA and KIFIB protein pleckstrin homology (PH) domain
    cd01365
    Location:4361
    KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
    pfam12423
    Location:805851
    KIF1B; Kinesin protein 1B
    pfam12473
    Location:11491296
    DUF3694; Kinesin protein
    pfam16183
    Location:358515
    Kinesin_assoc; Kinesin-associated

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    240713767..240821403 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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