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ZNF716 zinc finger protein 716 [ Homo sapiens (human) ]

Gene ID: 441234, updated on 12-Oct-2019

Summary

Official Symbol
ZNF716provided by HGNC
Official Full Name
zinc finger protein 716provided by HGNC
Primary source
HGNC:HGNC:32458
See related
Ensembl:ENSG00000182111
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more

Genomic context

See ZNF716 in Genome Data Viewer
Location:
7p11.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (57450177..57473559)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (57509883..57533265)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene vomeronasal 1 receptor 28 pseudogene Neighboring gene suppressor APC domain containing 2 pseudogene 2 Neighboring gene vomeronasal 1 receptor 29 pseudogene Neighboring gene uncharacterized LOC105375300

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.
NHGRI GWA Catalog

Pathways from BioSystems

  • Gene Expression, organism-specific biosystem (from REACTOME)
    Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
  • Generic Transcription Pathway, organism-specific biosystem (from REACTOME)
    Generic Transcription Pathway, organism-specific biosystemOVERVIEW OF TRANSCRIPTION REGULATION: Detailed studies of gene transcription regulation in a wide variety of eukaryotic systems has revealed the general principles and mechanisms by which cell- or t...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ46189

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159279.1NP_001152751.1  zinc finger protein 716

    See identical proteins and their annotated locations for NP_001152751.1

    Status: VALIDATED

    Source sequence(s)
    AC092175, AK131575
    Consensus CDS
    CCDS55112.1
    UniProtKB/Swiss-Prot
    A6NP11
    Related
    ENSP00000394248.1, ENST00000420713.2
    Conserved Domains (6) summary
    smart00349
    Location:1676
    KRAB; krueppel associated box
    COG5048
    Location:211494
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298318
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1655
    KRAB; KRAB box
    pfam13465
    Location:228251
    zf-H2C2_2; Zinc-finger double domain
    pfam14353
    Location:353398
    CpXC; CpXC protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    57450177..57473559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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