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ZNF737 zinc finger protein 737 [ Homo sapiens (human) ]

Gene ID: 100129842, updated on 5-Aug-2022

Summary

Official Symbol
ZNF737provided by HGNC
Official Full Name
zinc finger protein 737provided by HGNC
Primary source
HGNC:HGNC:32468
See related
Ensembl:ENSG00000237440 MIM:603984; AllianceGenome:HGNC:32468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF102
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thyroid (RPKM 7.4), ovary (RPKM 4.3) and 23 other tissues See more
Orthologs
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Genomic context

See ZNF737 in Genome Data Viewer
Location:
19p12
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (20530276..20565781, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (20675528..20703634, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (20720798..20748587, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 826, pseudogene Neighboring gene uncharacterized LOC124904663 Neighboring gene BCL2 interacting protein 3 pseudogene 22 Neighboring gene uncharacterized LOC105372317 Neighboring gene BCL2 interacting protein 3 pseudogene 23 Neighboring gene uncharacterized LOC105372316 Neighboring gene vomeronasal 1 receptor 78 pseudogene Neighboring gene uncharacterized LOC105372318

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 737
Names
zinc finger protein 102 (Y3)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159293.2NP_001152765.1  zinc finger protein 737

    See identical proteins and their annotated locations for NP_001152765.1

    Status: VALIDATED

    Source sequence(s)
    AC008554, AI857360, BC015765, DA043454
    Consensus CDS
    CCDS54238.1
    UniProtKB/Swiss-Prot
    C9JHM3, O75373
    Related
    ENSP00000395733.3, ENST00000427401.9
    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:143529
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:383408
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    20530276..20565781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006722597.5XP_006722660.1  zinc finger protein 737 isoform X2

    See identical proteins and their annotated locations for XP_006722660.1

    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:143528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:383408
    zf-H2C2_2; Zinc-finger double domain
  2. XM_005259697.5XP_005259754.1  zinc finger protein 737 isoform X1

    See identical proteins and their annotated locations for XP_005259754.1

    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:143528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:383408
    zf-H2C2_2; Zinc-finger double domain
  3. XM_047438008.1XP_047293964.1  zinc finger protein 737 isoform X5

  4. XM_017026117.3XP_016881606.1  zinc finger protein 737 isoform X6

  5. XM_011527598.4XP_011525900.1  zinc finger protein 737 isoform X1

    See identical proteins and their annotated locations for XP_011525900.1

    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:143528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:383408
    zf-H2C2_2; Zinc-finger double domain
  6. XM_011527599.4XP_011525901.1  zinc finger protein 737 isoform X2

    See identical proteins and their annotated locations for XP_011525901.1

    Conserved Domains (5) summary
    smart00349
    Location:462
    KRAB; krueppel associated box
    COG5048
    Location:143528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:427447
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:643
    KRAB; KRAB box
    pfam13465
    Location:383408
    zf-H2C2_2; Zinc-finger double domain
  7. XM_047438007.1XP_047293963.1  zinc finger protein 737 isoform X4

  8. XM_047438006.1XP_047293962.1  zinc finger protein 737 isoform X3

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    20675528..20703634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)