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    Apc APC, WNT signaling pathway regulator [ Mus musculus (house mouse) ]

    Gene ID: 11789, updated on 21-Sep-2021

    Summary

    Official Symbol
    Apcprovided by MGI
    Official Full Name
    APC, WNT signaling pathway regulatorprovided by MGI
    Primary source
    MGI:MGI:88039
    See related
    Ensembl:ENSMUSG00000005871
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    M; CC1; Min; mAPC; AI047805; AU020952; AW124434
    Expression
    Broad expression in frontal lobe adult (RPKM 29.9), CNS E18 (RPKM 22.5) and 18 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Apc in Genome Data Viewer
    Location:
    18 B1; 18 18.53 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (34353350..34455243)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (34220297..34322190)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (34380638..34481844)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41686 Neighboring gene predicted gene, 23411 Neighboring gene ribosomal protein L29 pseudogene Neighboring gene predicted gene, 54017 Neighboring gene signal recognition particle 19 Neighboring gene receptor accessory protein 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables beta-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables beta-catenin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables beta-catenin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables dynein complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables dynein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables gamma-catenin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables gamma-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule plus-end binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables microtubule plus-end binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protease binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within Wnt signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within anterior/posterior pattern specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within axis specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within axonogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within canonical Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within canonical Wnt signaling pathway involved in negative regulation of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within canonical Wnt signaling pathway involved in positive regulation of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cell fate specification IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to DNA damage stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within chromosome organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within chromosome organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cytoplasmic microtubule organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within dorsal/ventral pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment or maintenance of cell polarity ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within hair follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in insulin receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in insulin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within metaphase/anaphase transition of mitotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within metaphase/anaphase transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mitotic spindle assembly checkpoint signaling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within muscle cell cellular homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of MAPK cascade IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of MAPK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cardiac muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of cell population proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cyclin-dependent protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of epithelial cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of epithelial cell proliferation involved in prostate gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of microtubule depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of microtubule depolymerization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of odontogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in pattern specification process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within pattern specification process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell death ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of cell division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cold-induced thermogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of microtubule polymerization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein localization to centrosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of protein localization to centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of pseudopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within proximal/distal pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of attachment of spindle microtubules to kinetochore IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of attachment of spindle microtubules to kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cell migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of epithelial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of glutamate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of microtubule-based process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of nitrogen compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of osteoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of osteoclast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within retina development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within skin development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within somatic stem cell population maintenance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within somatic stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within stem cell population maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within thymus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Scrib-APC-beta-catenin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with adherens junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axonal growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axonal growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    part_of beta-catenin destruction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of beta-catenin destruction complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catenin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell body fiber ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell cortex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell projection membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with cytoplasmic microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuron projection terminus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    colocalizes_with plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    adenomatous polyposis coli protein
    Names
    adenomatosis polyposis coli
    multiple intestinal neoplasia

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360979.1NP_001347908.1  adenomatous polyposis coli protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC090534, AC114003, AL591373
      Conserved Domains (15) summary
      smart00185
      Location:588628
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:404447
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:630668
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15761599
      APC_r; APC repeat
      pfam05924
      Location:19731992
      SAMP; SAMP Motif
      pfam05937
      Location:26112783
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21642509
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:671958
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9751074
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12221308
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16011654
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16851778
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18121886
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    2. NM_001360980.1NP_001347909.1  adenomatous polyposis coli protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC090534, AC114003, AL591373
      Conserved Domains (16) summary
      smart00185
      Location:665705
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:579611
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:707745
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16531676
      APC_r; APC repeat
      pfam05924
      Location:20502069
      SAMP; SAMP Motif
      pfam05937
      Location:26882860
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22412586
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7481035
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10521151
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12991385
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16781731
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17621855
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18891963
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:391464
      APC_rep; Adenomatous polyposis coli (APC) repeat
    3. NM_007462.3NP_031488.2  adenomatous polyposis coli protein isoform 3

      See identical proteins and their annotated locations for NP_031488.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an exon in the coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
      Source sequence(s)
      AC090534, AK080907, AL591373, BE623286
      Consensus CDS
      CCDS29125.1
      UniProtKB/TrEMBL
      B2RUG9, Q8BNP7
      Related
      ENSMUSP00000078337.6, ENSMUST00000079362.13
      Conserved Domains (16) summary
      smart00185
      Location:647687
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:463506
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:689727
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16351658
      APC_r; APC repeat
      pfam05924
      Location:20322051
      SAMP; SAMP Motif
      pfam05937
      Location:26702842
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22232568
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7301017
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10341133
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12811367
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16601713
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17441837
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18711945
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:391464
      APC_rep; Adenomatous polyposis coli (APC) repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      34353350..34455243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525529.4XP_006525592.1  adenomatous polyposis coli protein isoform X1

      Conserved Domains (15) summary
      smart00185
      Location:675715
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:589621
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:717755
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16631686
      APC_r; APC repeat
      pfam05924
      Location:20602079
      SAMP; SAMP Motif
      pfam05937
      Location:26982870
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22512596
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7581045
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10621161
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:13091395
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16881741
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17721865
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18991973
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:401474
      APC_rep; Adenomatous polyposis coli (APC) repeat
    2. XM_006525538.4XP_006525601.1  adenomatous polyposis coli protein isoform X15

      Conserved Domains (15) summary
      smart00185
      Location:574614
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:488520
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:616654
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15621585
      APC_r; APC repeat
      pfam05924
      Location:19591978
      SAMP; SAMP Motif
      pfam05937
      Location:25972769
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21502495
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:657944
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9611060
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12081294
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15871640
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16711764
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17981872
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:315373
      APC_rep; Adenomatous polyposis coli (APC) repeat
    3. XM_006525534.4XP_006525597.1  adenomatous polyposis coli protein isoform X6

      Conserved Domains (15) summary
      smart00185
      Location:640680
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:554586
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:682720
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16281651
      APC_r; APC repeat
      pfam05924
      Location:20252044
      SAMP; SAMP Motif
      pfam05937
      Location:26632835
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22162561
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7231010
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10271126
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12741360
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16531706
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17371830
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18641938
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:366439
      APC_rep; Adenomatous polyposis coli (APC) repeat
    4. XM_036160948.1XP_036016841.1  adenomatous polyposis coli protein isoform X21

      Conserved Domains (15) summary
      smart00185
      Location:539579
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:453485
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:581621
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15271550
      APC_r; APC repeat
      pfam05924
      Location:19241943
      SAMP; SAMP Motif
      pfam05937
      Location:25622734
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21152460
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:622909
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9261025
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11731259
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15521605
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16361729
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17631837
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:280338
      APC_rep; Adenomatous polyposis coli (APC) repeat
    5. XM_036160950.1XP_036016843.1  adenomatous polyposis coli protein isoform X24

      Conserved Domains (15) summary
      smart00185
      Location:521561
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:337380
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:563603
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15091532
      APC_r; APC repeat
      pfam05924
      Location:19061925
      SAMP; SAMP Motif
      pfam05937
      Location:25442716
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20972442
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:604891
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9081007
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11551241
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15341587
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16181711
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17451819
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:280338
      APC_rep; Adenomatous polyposis coli (APC) repeat
    6. XM_030250280.1XP_030106140.1  adenomatous polyposis coli protein isoform X9

      Conserved Domains (15) summary
      smart00185
      Location:622662
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:438481
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:664702
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16101633
      APC_r; APC repeat
      pfam05924
      Location:20072026
      SAMP; SAMP Motif
      pfam05937
      Location:26452817
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21982543
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:705992
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10091108
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12561342
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16351688
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17191812
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18461920
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:366439
      APC_rep; Adenomatous polyposis coli (APC) repeat
    7. XM_030250290.2XP_030106150.1  adenomatous polyposis coli protein isoform X17

      Conserved Domains (16) summary
      smart00185
      Location:564604
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:478510
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:606644
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15521575
      APC_r; APC repeat
      pfam05924
      Location:19491968
      SAMP; SAMP Motif
      pfam05937
      Location:25872759
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21402485
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:647934
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9511050
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11981284
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15771630
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16611754
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17881862
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:305363
      APC_rep; Adenomatous polyposis coli (APC) repeat
    8. XM_036160944.1XP_036016837.1  adenomatous polyposis coli protein isoform X7

      Conserved Domains (16) summary
      smart00185
      Location:630670
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:544576
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:672712
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16181641
      APC_r; APC repeat
      pfam05924
      Location:20152034
      SAMP; SAMP Motif
      pfam05937
      Location:26532825
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22062551
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7131000
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10171116
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12641350
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16431696
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17271820
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18541928
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:356429
      APC_rep; Adenomatous polyposis coli (APC) repeat
    9. XM_036160951.1XP_036016844.1  adenomatous polyposis coli protein isoform X25

      Related
      ENSMUSP00000111447.4, ENSMUST00000115781.10
      Conserved Domains (16) summary
      smart00185
      Location:511551
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:327370
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:553593
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:14991522
      APC_r; APC repeat
      pfam05924
      Location:18961915
      SAMP; SAMP Motif
      pfam05937
      Location:25342706
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20872432
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:594881
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:898997
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11451231
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15241577
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16081701
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17351809
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:270328
      APC_rep; Adenomatous polyposis coli (APC) repeat
    10. XM_006525530.3XP_006525593.1  adenomatous polyposis coli protein isoform X2

      See identical proteins and their annotated locations for XP_006525593.1

      Conserved Domains (16) summary
      smart00185
      Location:665705
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:579611
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:707745
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16531676
      APC_r; APC repeat
      pfam05924
      Location:20502069
      SAMP; SAMP Motif
      pfam05937
      Location:26882860
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22412586
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7481035
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10521151
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12991385
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16781731
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17621855
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18891963
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:391464
      APC_rep; Adenomatous polyposis coli (APC) repeat
    11. XM_006525539.4XP_006525602.1  adenomatous polyposis coli protein isoform X20

      Conserved Domains (16) summary
      smart00185
      Location:546586
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:362405
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:588628
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15341557
      APC_r; APC repeat
      pfam05924
      Location:19311950
      SAMP; SAMP Motif
      pfam05937
      Location:25692741
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21222467
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:629916
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9331032
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11801266
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15591612
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16431736
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17701844
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:305363
      APC_rep; Adenomatous polyposis coli (APC) repeat
    12. XM_030250281.2XP_030106141.1  adenomatous polyposis coli protein isoform X10

      Conserved Domains (16) summary
      smart00185
      Location:612652
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:428471
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:654694
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16001623
      APC_r; APC repeat
      pfam05924
      Location:19972016
      SAMP; SAMP Motif
      pfam05937
      Location:26352807
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21882533
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:695982
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9991098
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12461332
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16251678
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17091802
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18361910
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:356429
      APC_rep; Adenomatous polyposis coli (APC) repeat
    13. XM_030250288.1XP_030106148.1  adenomatous polyposis coli protein isoform X16

      Conserved Domains (15) summary
      smart00185
      Location:571611
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:485517
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:613651
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15591582
      APC_r; APC repeat
      pfam05924
      Location:19561975
      SAMP; SAMP Motif
      pfam05937
      Location:25942766
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21472492
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:654941
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9581057
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12051291
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15841637
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16681761
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17951869
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:297370
      APC_rep; Adenomatous polyposis coli (APC) repeat
    14. XM_030250283.1XP_030106143.1  adenomatous polyposis coli protein isoform X12

      Conserved Domains (15) summary
      smart00185
      Location:606646
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:520552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:648688
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15941617
      APC_r; APC repeat
      pfam05924
      Location:19912010
      SAMP; SAMP Motif
      pfam05937
      Location:26292801
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21822527
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:689976
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9931092
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12401326
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16191672
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17031796
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18301904
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    15. XM_036160952.1XP_036016845.1  adenomatous polyposis coli protein isoform X26

      Conserved Domains (15) summary
      smart00185
      Location:487527
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:303346
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:529569
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:14751498
      APC_r; APC repeat
      pfam05924
      Location:18721891
      SAMP; SAMP Motif
      pfam05937
      Location:25102682
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20632408
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:570857
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:874973
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11211207
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15001553
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:15841677
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17111785
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:246304
      APC_rep; Adenomatous polyposis coli (APC) repeat
    16. XM_006525532.5XP_006525595.1  adenomatous polyposis coli protein isoform X3

      See identical proteins and their annotated locations for XP_006525595.1

      Conserved Domains (15) summary
      smart00185
      Location:657697
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:473516
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:699737
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16451668
      APC_r; APC repeat
      pfam05924
      Location:20422061
      SAMP; SAMP Motif
      pfam05937
      Location:26802852
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22332578
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7401027
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10441143
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12911377
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16701723
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17541847
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18811955
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:401474
      APC_rep; Adenomatous polyposis coli (APC) repeat
    17. XM_030250286.2XP_030106146.1  adenomatous polyposis coli protein isoform X14

      Conserved Domains (15) summary
      smart00185
      Location:588628
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:404447
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:630668
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15761599
      APC_r; APC repeat
      pfam05924
      Location:19731992
      SAMP; SAMP Motif
      pfam05937
      Location:26112783
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21642509
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:671958
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9751074
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12221308
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16011654
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16851778
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18121886
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    18. XM_030250278.2XP_030106138.1  adenomatous polyposis coli protein isoform X7

      Conserved Domains (16) summary
      smart00185
      Location:630670
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:544576
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:672712
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16181641
      APC_r; APC repeat
      pfam05924
      Location:20152034
      SAMP; SAMP Motif
      pfam05937
      Location:26532825
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22062551
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7131000
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10171116
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12641350
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16431696
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17271820
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18541928
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:356429
      APC_rep; Adenomatous polyposis coli (APC) repeat
    19. XM_030250291.1XP_030106151.1  adenomatous polyposis coli protein isoform X18

      Conserved Domains (15) summary
      smart00185
      Location:556596
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:372415
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:598636
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15441567
      APC_r; APC repeat
      pfam05924
      Location:19411960
      SAMP; SAMP Motif
      pfam05937
      Location:25792751
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21322477
      APC_basic; APC basic domain
      pfam11414
      Location:135215
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:639926
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9431042
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11901276
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15691622
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16531746
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17801854
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:315373
      APC_rep; Adenomatous polyposis coli (APC) repeat
    20. XM_036160946.1XP_036016839.1  adenomatous polyposis coli protein isoform X12

      Conserved Domains (15) summary
      smart00185
      Location:606646
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:520552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:648688
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15941617
      APC_r; APC repeat
      pfam05924
      Location:19912010
      SAMP; SAMP Motif
      pfam05937
      Location:26292801
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21822527
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:689976
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9931092
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12401326
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16191672
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17031796
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18301904
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    21. XM_030250293.2XP_030106153.1  adenomatous polyposis coli protein isoform X22

      Conserved Domains (17) summary
      smart00185
      Location:529569
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:443475
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:571609
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15171540
      APC_r; APC repeat
      pfam05924
      Location:19141933
      SAMP; SAMP Motif
      pfam05937
      Location:25522724
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21052450
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:612899
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9161015
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11631249
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15421595
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16261719
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17531827
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:270328
      APC_rep; Adenomatous polyposis coli (APC) repeat
      cl00755
      Location:172296
      zf-dskA_traR; Prokaryotic dksA/traR C4-type zinc finger
    22. XM_030250294.2XP_030106154.1  adenomatous polyposis coli protein isoform X25

      Conserved Domains (16) summary
      smart00185
      Location:511551
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:327370
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:553593
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:14991522
      APC_r; APC repeat
      pfam05924
      Location:18961915
      SAMP; SAMP Motif
      pfam05937
      Location:25342706
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20872432
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:594881
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:898997
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11451231
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15241577
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16081701
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17351809
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:270328
      APC_rep; Adenomatous polyposis coli (APC) repeat
    23. XM_030250282.2XP_030106142.1  adenomatous polyposis coli protein isoform X11

      Conserved Domains (15) summary
      smart00185
      Location:610650
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:524556
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:652690
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15981621
      APC_r; APC repeat
      pfam05924
      Location:19952014
      SAMP; SAMP Motif
      pfam05937
      Location:26332805
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21862531
      APC_basic; APC basic domain
      pfam11414
      Location:105185
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:693980
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9971096
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12441330
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16231676
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17071800
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18341908
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:336409
      APC_rep; Adenomatous polyposis coli (APC) repeat
    24. XM_030250277.2XP_030106137.1  adenomatous polyposis coli protein isoform X4

      Conserved Domains (16) summary
      smart00185
      Location:647687
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:463506
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:689727
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16351658
      APC_r; APC repeat
      pfam05924
      Location:20322051
      SAMP; SAMP Motif
      pfam05937
      Location:26702842
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22232568
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7301017
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10341133
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12811367
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16601713
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17441837
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18711945
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam18797
      Location:391464
      APC_rep; Adenomatous polyposis coli (APC) repeat
    25. XM_030250279.2XP_030106139.1  adenomatous polyposis coli protein isoform X8

      Conserved Domains (15) summary
      smart00185
      Location:627667
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:443486
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:669707
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16151638
      APC_r; APC repeat
      pfam05924
      Location:20122031
      SAMP; SAMP Motif
      pfam05937
      Location:26502822
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22032548
      APC_basic; APC basic domain
      pfam11414
      Location:105185
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:710997
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10141113
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12611347
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16401693
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17241817
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18511925
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:371444
      APC_rep; Adenomatous polyposis coli (APC) repeat
    26. XM_036160947.1XP_036016840.1  adenomatous polyposis coli protein isoform X20

      Conserved Domains (16) summary
      smart00185
      Location:546586
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:362405
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:588628
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15341557
      APC_r; APC repeat
      pfam05924
      Location:19311950
      SAMP; SAMP Motif
      pfam05937
      Location:25692741
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21222467
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:629916
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9331032
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11801266
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15591612
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16431736
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17701844
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:305363
      APC_rep; Adenomatous polyposis coli (APC) repeat
    27. XM_036160945.1XP_036016838.1  adenomatous polyposis coli protein isoform X10

      Conserved Domains (16) summary
      smart00185
      Location:612652
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:428471
      ARM; armadillo repeat [structural motif]
      pfam16689
      Location:455
      APC_N_CC; Coiled-coil N-terminus of APC, dimerization domain
      pfam00514
      Location:654694
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16001623
      APC_r; APC repeat
      pfam05924
      Location:19972016
      SAMP; SAMP Motif
      pfam05937
      Location:26352807
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21882533
      APC_basic; APC basic domain
      pfam11414
      Location:125205
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:695982
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9991098
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12461332
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16251678
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17091802
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18361910
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:356429
      APC_rep; Adenomatous polyposis coli (APC) repeat
    28. XM_006525533.4XP_006525596.1  adenomatous polyposis coli protein isoform X5

      Conserved Domains (15) summary
      smart00185
      Location:645685
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:559591
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:687725
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:16331656
      APC_r; APC repeat
      pfam05924
      Location:20302049
      SAMP; SAMP Motif
      pfam05937
      Location:26682840
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:22212566
      APC_basic; APC basic domain
      pfam11414
      Location:105185
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:7281015
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:10321131
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12791365
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16581711
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17421835
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18691943
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:371444
      APC_rep; Adenomatous polyposis coli (APC) repeat
    29. XM_036160949.1XP_036016842.1  adenomatous polyposis coli protein isoform X23

      Conserved Domains (15) summary
      smart00185
      Location:526566
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:342385
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:568608
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15141537
      APC_r; APC repeat
      pfam05924
      Location:19111930
      SAMP; SAMP Motif
      pfam05937
      Location:25492721
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21022447
      APC_basic; APC basic domain
      pfam11414
      Location:105185
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:609896
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9131012
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11601246
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15391592
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16231716
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17501824
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:285343
      APC_rep; Adenomatous polyposis coli (APC) repeat
    30. XM_030250285.2XP_030106145.1  adenomatous polyposis coli protein isoform X13

      Conserved Domains (15) summary
      smart00185
      Location:592632
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:408451
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:634672
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15801603
      APC_r; APC repeat
      pfam05924
      Location:19771996
      SAMP; SAMP Motif
      pfam05937
      Location:26152787
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21682513
      APC_basic; APC basic domain
      pfam11414
      Location:105185
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:675962
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9791078
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12261312
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16051658
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16891782
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18161890
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:336409
      APC_rep; Adenomatous polyposis coli (APC) repeat
    31. XM_030250287.2XP_030106147.1  adenomatous polyposis coli protein isoform X14

      Conserved Domains (15) summary
      smart00185
      Location:588628
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:404447
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:630668
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15761599
      APC_r; APC repeat
      pfam05924
      Location:19731992
      SAMP; SAMP Motif
      pfam05937
      Location:26112783
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21642509
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:671958
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9751074
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12221308
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16011654
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16851778
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18121886
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    32. XM_030250289.2XP_030106149.1  adenomatous polyposis coli protein isoform X16

      Conserved Domains (15) summary
      smart00185
      Location:571611
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:485517
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:613651
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15591582
      APC_r; APC repeat
      pfam05924
      Location:19561975
      SAMP; SAMP Motif
      pfam05937
      Location:25942766
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21472492
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:654941
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9581057
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12051291
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15841637
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16681761
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17951869
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:297370
      APC_rep; Adenomatous polyposis coli (APC) repeat
    33. XM_006525536.5XP_006525599.1  adenomatous polyposis coli protein isoform X12

      See identical proteins and their annotated locations for XP_006525599.1

      Conserved Domains (15) summary
      smart00185
      Location:606646
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:520552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:648688
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15941617
      APC_r; APC repeat
      pfam05924
      Location:19912010
      SAMP; SAMP Motif
      pfam05937
      Location:26292801
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21822527
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:689976
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9931092
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12401326
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16191672
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17031796
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18301904
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    34. XM_030250296.2XP_030106156.1  adenomatous polyposis coli protein isoform X26

      Conserved Domains (15) summary
      smart00185
      Location:487527
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:303346
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:529569
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:14751498
      APC_r; APC repeat
      pfam05924
      Location:18721891
      SAMP; SAMP Motif
      pfam05937
      Location:25102682
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20632408
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:570857
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:874973
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11211207
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15001553
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:15841677
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17111785
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:246304
      APC_rep; Adenomatous polyposis coli (APC) repeat
    35. XM_030250292.2XP_030106152.1  adenomatous polyposis coli protein isoform X19

      Conserved Domains (15) summary
      smart00185
      Location:553593
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:369412
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:595633
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15411564
      APC_r; APC repeat
      pfam05924
      Location:19381957
      SAMP; SAMP Motif
      pfam05937
      Location:25762748
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21292474
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:636923
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9401039
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11871273
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15661619
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:16501743
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17771851
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:297370
      APC_rep; Adenomatous polyposis coli (APC) repeat
    36. XM_030250284.2XP_030106144.1  adenomatous polyposis coli protein isoform X12

      Conserved Domains (15) summary
      smart00185
      Location:606646
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:520552
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:648688
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:15941617
      APC_r; APC repeat
      pfam05924
      Location:19912010
      SAMP; SAMP Motif
      pfam05937
      Location:26292801
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:21822527
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:689976
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:9931092
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:12401326
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:16191672
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:17031796
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:18301904
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:332405
      APC_rep; Adenomatous polyposis coli (APC) repeat
    37. XM_030250295.2XP_030106155.1  adenomatous polyposis coli protein isoform X26

      Conserved Domains (15) summary
      smart00185
      Location:487527
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:303346
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:529569
      Arm; Armadillo/beta-catenin-like repeat
      pfam05923
      Location:14751498
      APC_r; APC repeat
      pfam05924
      Location:18721891
      SAMP; SAMP Motif
      pfam05937
      Location:25102682
      EB1_binding; EB-1 Binding Domain
      pfam05956
      Location:20632408
      APC_basic; APC basic domain
      pfam11414
      Location:66146
      Suppressor_APC; Adenomatous polyposis coli tumor suppressor protein
      pfam16629
      Location:570857
      Arm_APC_u3; Armadillo-associated region on APC
      pfam16630
      Location:874973
      APC_u5; Unstructured region on APC between 1st and 2nd catenin-bdg motifs
      pfam16633
      Location:11211207
      APC_u9; Unstructured region on APC between 1st two creatine-rich regions
      pfam16634
      Location:15001553
      APC_u13; Unstructured region on APC between APC_crr and SAMP
      pfam16635
      Location:15841677
      APC_u14; Unstructured region on APC between SAMP and APC_crr
      pfam16636
      Location:17111785
      APC_u15; Unstructured region on APC between APC_crr regions 5 and 6
      pfam18797
      Location:246304
      APC_rep; Adenomatous polyposis coli (APC) repeat
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