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Zscan29 zinc finger SCAN domains 29 [ Mus musculus (house mouse) ]

Gene ID: 99334, updated on 8-Nov-2022

Summary

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Official Symbol
Zscan29provided by MGI
Official Full Name
zinc finger SCAN domains 29provided by MGI
Primary source
MGI:MGI:2139317
See related
Ensembl:ENSMUSG00000050619 AllianceGenome:MGI:2139317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp690
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in bladder; telencephalon ventricular layer; and testis. Orthologous to human ZSCAN29 (zinc finger and SCAN domain containing 29). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 2.7), bladder adult (RPKM 2.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zscan29 in Genome Data Viewer
Location:
2; 2 E5
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120988754..121001645, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (121158273..121171148, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 23858 Neighboring gene leucine carboxyl methyltransferase 2 Neighboring gene adenosine deaminase-like Neighboring gene tubulin, gamma complex associated protein 4 Neighboring gene transformation related protein 53 binding protein 1 Neighboring gene microtubule-associated protein 1 A Neighboring gene diphosphoinositol pentakisphosphate kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
  2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC117957

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
zinc finger and SCAN domain-containing protein 29
Names
zinc finger protein 690

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290819.1 → NP_001277748.1  zinc finger and SCAN domain-containing protein 29 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). The exon combination of this variant is inferred based on partial mouse transcript alignments and full-length orthologous human alignments.
    Source sequence(s)
    AK031943, AK050477, AL845479, BM937526, BP768866, CV555944
    Consensus CDS
    CCDS71123.1
    UniProtKB/TrEMBL
    A2ARU5, Q8BGW7
    Related
    ENSMUSP00000106289.3, ENSMUST00000110661.9
    Conserved Domains (7) summary
    smart00431
    Location:13 → 123
    SCAN; leucine rich region
    COG5048
    Location:663 → 823
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:667 → 687
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:777 → 799
    zf-C2H2; Zinc finger, C2H2 type
    pfam02023
    Location:13 → 101
    SCAN; SCAN domain
    pfam13465
    Location:735 → 760
    zf-H2C2_2; Zinc-finger double domain
    pfam13837
    Location:399 → 480
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  2. NM_001290820.1 → NP_001277749.1  zinc finger and SCAN domain-containing protein 29 isoform b

    See identical proteins and their annotated locations for NP_001277749.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) initiates translation at an alternate start codon, lacks two 3' exons but instead contains an alternate 3' terminal exon, and it thus differs in its 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has distinct N- and C-termini and is shorter than isoform a.
    Source sequence(s)
    AI481103, AK031943, AK050477
    UniProtKB/TrEMBL
    Q8BGW7
    Conserved Domains (1) summary
    pfam13837
    Location:132 → 213
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    120988754..121001645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500482.5 → XP_006500545.1  zinc finger and SCAN domain-containing protein 29 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:557 → 717
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:561 → 581
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13837
    Location:293 → 378
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178889.4: Suppressed sequence

    Description
    NM_178889.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version

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