Format

Send to:

Choose Destination

CHURC1 churchill domain containing 1 [ Homo sapiens (human) ]

Gene ID: 91612, updated on 13-Mar-2020

Summary

Official Symbol
CHURC1provided by HGNC
Official Full Name
churchill domain containing 1provided by HGNC
Primary source
HGNC:HGNC:20099
See related
Ensembl:ENSG00000258289 MIM:608577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
chch; My015; C14orf52
Expression
Ubiquitous expression in fat (RPKM 18.1), brain (RPKM 17.2) and 25 other tissues See more
Orthologs

Genomic context

See CHURC1 in Genome Data Viewer
Location:
14q23.3
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (64914361..64935368)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (65381079..65410635)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370534 Neighboring gene CHURC1-FNTB readthrough Neighboring gene ribonuclease P RNA component H1, 2 pseudogene Neighboring gene glutathione peroxidase 2 Neighboring gene RAB15, member RAS oncogene family

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough CHURC1-FNTB

Readthrough gene: CHURC1-FNTB, Included gene: FNTB

Homology

Clone Names

  • FLJ33064, FLJ51978, FLJ78804

Gene Ontology Provided by GOA

Function Evidence Code Pubs
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204063.1NP_001190992.1  protein Churchill isoform 2

    See identical proteins and their annotated locations for NP_001190992.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK057626, AL139022, AV734503, BC010517
    Consensus CDS
    CCDS55921.1
    UniProtKB/Swiss-Prot
    Q8WUH1
    UniProtKB/TrEMBL
    A0A024R6B7
    Related
    ENSP00000448050.1, ENST00000549115.5
    Conserved Domains (1) summary
    pfam06573
    Location:28138
    Churchill; Churchill protein
  2. NM_001204064.1NP_001190993.1  protein Churchill isoform 3

    See identical proteins and their annotated locations for NP_001190993.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
    Source sequence(s)
    AL135745, AL139022, AV734503, BC010517, BP305870
    Consensus CDS
    CCDS55922.1
    UniProtKB/Swiss-Prot
    Q8WUH1
    Related
    ENSP00000450165.2, ENST00000548752.6
    Conserved Domains (1) summary
    pfam06573
    Location:2887
    Churchill; Churchill protein
  3. NM_145165.3NP_660148.3  protein Churchill isoform 1

    See identical proteins and their annotated locations for NP_660148.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AF060510, AL139022, AV734503, BC010517
    Consensus CDS
    CCDS32101.2
    UniProtKB/Swiss-Prot
    Q8WUH1
    Related
    ENSP00000475473.1, ENST00000607599.5
    Conserved Domains (1) summary
    pfam06573
    Location:28139
    Churchill; Churchill protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    64914361..64935368
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center