U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Churc1 churchill domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 211151, updated on 5-Mar-2024

Summary

Official Symbol
Churc1provided by MGI
Official Full Name
churchill domain containing 1provided by MGI
Primary source
MGI:MGI:1923684
See related
Ensembl:ENSMUSG00000090258 AllianceGenome:MGI:1923684
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
chch; My015; 1700030P15Rik
Summary
Predicted to enable DNA binding activity. Predicted to be involved in fibroblast growth factor receptor signaling pathway. Predicted to act upstream of or within mesoderm development and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in brain; cranial ganglion; and dorsal root ganglion. Orthologous to human CHURC1 (churchill domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 32.2), heart adult (RPKM 23.6) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
12 C3; 12 33.73 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76812312..76829954)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76765538..76783180)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7148 Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 3 Neighboring gene expressed sequence AI463170 Neighboring gene STARR-seq mESC enhancer starr_32529 Neighboring gene STARR-seq mESC enhancer starr_32530 Neighboring gene STARR-positive B cell enhancer ABC_E8490 Neighboring gene spectrin beta, erythrocytic Neighboring gene STARR-seq mESC enhancer starr_32532 Neighboring gene STARR-seq mESC enhancer starr_32533 Neighboring gene glutathione peroxidase 2 Neighboring gene RAB15, member RAS oncogene family Neighboring gene predicted gene, 34988

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

Markers

Clone Names

  • 1700030P15Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus ISA
Inferred from Sequence Alignment
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_206534.2NP_996257.1  protein Churchill

    See identical proteins and their annotated locations for NP_996257.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC132331, BC076499
    Consensus CDS
    CCDS36478.1
    UniProtKB/Swiss-Prot
    Q6DG52, Q8VCP1
    Related
    ENSMUSP00000047015.8, ENSMUST00000041262.14
    Conserved Domains (1) summary
    pfam06573
    Location:1111
    Churchill; Churchill protein

RNA

  1. NR_154884.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon in the 5' region, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
    Source sequence(s)
    AC132331, BC076499, BQ044298, BY089267
    Related
    ENSMUST00000126408.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    76812312..76829954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)