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SORBS2 sorbin and SH3 domain containing 2 [ Homo sapiens (human) ]

Gene ID: 8470, updated on 13-Mar-2020

Summary

Official Symbol
SORBS2provided by HGNC
Official Full Name
sorbin and SH3 domain containing 2provided by HGNC
Primary source
HGNC:HGNC:24098
See related
Ensembl:ENSG00000154556 MIM:616349
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARGBP2; PRO0618
Summary
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Expression
Broad expression in heart (RPKM 46.6), adrenal (RPKM 26.3) and 19 other tissues See more
Orthologs

Genomic context

See SORBS2 in Genome Data Viewer
Location:
4q35.1
Exon count:
37
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (185585444..185956372, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (186506598..186877870, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 3 Neighboring gene VISTA enhancer hs2502 Neighboring gene uncharacterized LOC101928929 Neighboring gene RNA, U4 small nuclear 64, pseudogene Neighboring gene toll like receptor 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
NHGRI GWA Catalog

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr upregulates SORBS2 in HeLa cells within 12 hours of exposure PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ93447, KIAA0777

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
cytoskeletal adaptor activity TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural constituent of cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
structural constituent of muscle TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament organization IEA
Inferred from Electronic Annotation
more info
 
biological_process ND
No biological Data available
more info
 
cell growth involved in cardiac muscle cell development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
Z disc NAS
Non-traceable Author Statement
more info
PubMed 
actin cytoskeleton TAS
Traceable Author Statement
more info
PubMed 
apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
focal adhesion IEA
Inferred from Electronic Annotation
more info
 
lamellipodium IEA
Inferred from Electronic Annotation
more info
 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
sorbin and SH3 domain-containing protein 2
Names
Arg binding protein 2
Arg/Abl-interacting protein 2
arg-binding protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029709.1 RefSeqGene

    Range
    5345..376273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001145670.1NP_001139142.1  sorbin and SH3 domain-containing protein 2 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) originates from an alternate promoter and has a different 5'UTR and first coding exon compared to variant 1. The resulting protein isoform (3) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, AK225327, AL134289, BC011883, DA105517
    Consensus CDS
    CCDS47173.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000397262.2, ENST00000449407.6
    Conserved Domains (3) summary
    smart00459
    Location:153198
    Sorb; Sorbin homologous domain
    cd11923
    Location:485541
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:584644
    SH3; Src Homology 3 domain superfamily
  2. NM_001145671.2NP_001139143.1  sorbin and SH3 domain-containing protein 2 isoform 4

    See identical proteins and their annotated locations for NP_001139143.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) originates from an alternate promoter and has a different 5'UTR and first coding exon and includes alternate in-frame exons compared to variant 1. The resulting protein isoform (4) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, BC011883, DA119376
    Consensus CDS
    CCDS47174.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000322182.9, ENST00000319471.13
    Conserved Domains (3) summary
    smart00459
    Location:153203
    Sorb; Sorbin homologous domain
    cd11923
    Location:572628
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:671731
    SH3; Src Homology 3 domain superfamily
  3. NM_001145672.1NP_001139144.1  sorbin and SH3 domain-containing protein 2 isoform 5

    See identical proteins and their annotated locations for NP_001139144.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) originates from an alternate promoter and has a different 5'UTR and first coding exon and includes alternate in-frame exons compared to variant 1. The resulting protein isoform (5) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, AC104805, AK293400, AV658263, BC011883, CN340607, DA139168
    Consensus CDS
    CCDS54825.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000409158.2, ENST00000448662.6
    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:502558
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:601661
    SH3; Src Homology 3 domain superfamily
  4. NM_001145673.2NP_001139145.1  sorbin and SH3 domain-containing protein 2 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) originates from an alternate promoter and has a different 5'UTR and first coding exon and includes alternate in-frame exons compared to variant 1. The resulting protein isoform (6) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, AK225812, AL134289, BC011883
    Consensus CDS
    CCDS47175.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000396008.2, ENST00000437304.6
    Conserved Domains (3) summary
    smart00459
    Location:246296
    Sorb; Sorbin homologous domain
    cd11923
    Location:665721
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:764824
    SH3; Src Homology 3 domain superfamily
  5. NM_001145674.1NP_001139146.1  sorbin and SH3 domain-containing protein 2 isoform 7

    See identical proteins and their annotated locations for NP_001139146.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) originates from an alternate promoter and has a different 5'UTR and first coding exon compared to variant 1. The resulting protein isoform (7) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, AK056628, AK296461, AV658263, CN340607, DA139168, DA836871
    Consensus CDS
    CCDS47176.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000397482.1, ENST00000418609.5
    Conserved Domains (4) summary
    cd11917
    Location:9441004
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:845901
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:829
    Sorb; Sorbin homologous domain
    cl17036
    Location:770824
    SH3; Src Homology 3 domain superfamily
  6. NM_001145675.2NP_001139147.1  sorbin and SH3 domain-containing protein 2 isoform 8

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) originates from an alternate promoter and has a different 5' UTR and first coding exon compared to variant 1. The resulting protein isoform (8) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC093797, AK304653, AV658263, CN340607, DA139168, DC421607
    UniProtKB/TrEMBL
    B7Z997
    Conserved Domains (3) summary
    cd11923
    Location:333389
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:436
    Sorb; Sorbin homologous domain
    cl17036
    Location:432492
    SH3; Src Homology 3 domain superfamily
  7. NM_001270771.2NP_001257700.1  sorbin and SH3 domain-containing protein 2 isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) originates from an alternate promoter, has a different 5' UTR, and several in-frame differences in the coding region compared to variant 1, which results in a longer isoform (7) compared to isoform 1.
    Source sequence(s)
    AB018320, AC093797, AK056628, BC035329, DA398113
    Consensus CDS
    CCDS59482.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000347852.5, ENST00000355634.9
    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11917
    Location:11401200
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:9661020
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10411097
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  8. NM_003603.6NP_003594.3  sorbin and SH3 domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_003594.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) differs at the 5' end, and contains a small in-frame insertion and a large in-frame deletion compared to transcript variant 2. It encodes a shorter isoform (1) with a different amino-terminal, but the same carboxy-terminal sequence containing three SH3 domains, as isoform 2.
    Source sequence(s)
    AC093797, AF049884, AK295742, BC011883, DA105517
    Consensus CDS
    CCDS43289.2
    UniProtKB/Swiss-Prot
    O94875
    UniProtKB/TrEMBL
    B7Z3D7
    Related
    ENSP00000377162.3, ENST00000393528.7
    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:507563
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:606666
    SH3; Src Homology 3 domain superfamily
  9. NM_021069.5NP_066547.1  sorbin and SH3 domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_066547.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs at the 5' end, and contains a large in-frame insertion and a small in-frame deletion compared to transcript variant 1. It encodes a longer isoform (2) with a different amino-terminal, but the same carboxy-terminal sequence containing three SH3 domains, as isoform 1.
    Source sequence(s)
    AB018320, AC093797, AC096659
    Consensus CDS
    CCDS3845.1
    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000284776.7, ENST00000284776.11
    Conserved Domains (4) summary
    smart00459
    Location:67117
    Sorb; Sorbin homologous domain
    cd11917
    Location:10401100
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:941997
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:866920
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    185585444..185956372 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017008756.2XP_016864245.1  sorbin and SH3 domain-containing protein 2 isoform X16

  2. XM_017008755.2XP_016864244.1  sorbin and SH3 domain-containing protein 2 isoform X15

    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:460516
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:814874
    SH3; Src Homology 3 domain superfamily
  3. XM_024454258.1XP_024310026.1  sorbin and SH3 domain-containing protein 2 isoform X13

    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:532588
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:886946
    SH3; Src Homology 3 domain superfamily
  4. XM_024454259.1XP_024310027.1  sorbin and SH3 domain-containing protein 2 isoform X14

    Conserved Domains (3) summary
    smart00459
    Location:67117
    Sorb; Sorbin homologous domain
    cd11923
    Location:461517
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:815875
    SH3; Src Homology 3 domain superfamily
  5. XM_017008771.2XP_016864260.1  sorbin and SH3 domain-containing protein 2 isoform X36

    UniProtKB/Swiss-Prot
    O94875
    Conserved Domains (3) summary
    smart00459
    Location:67117
    Sorb; Sorbin homologous domain
    cd11923
    Location:486542
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:585645
    SH3; Src Homology 3 domain superfamily
  6. XM_017008759.2XP_016864248.1  sorbin and SH3 domain-containing protein 2 isoform X20

  7. XM_017008768.2XP_016864257.1  sorbin and SH3 domain-containing protein 2 isoform X33

  8. XM_017008763.2XP_016864252.1  sorbin and SH3 domain-containing protein 2 isoform X29

  9. XM_017008758.2XP_016864247.1  sorbin and SH3 domain-containing protein 2 isoform X18

  10. XM_017008772.2XP_016864261.1  sorbin and SH3 domain-containing protein 2 isoform X37

  11. XM_024454260.1XP_024310028.1  sorbin and SH3 domain-containing protein 2 isoform X15

    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:460516
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:814874
    SH3; Src Homology 3 domain superfamily
  12. XM_005263312.2XP_005263369.1  sorbin and SH3 domain-containing protein 2 isoform X26

    UniProtKB/Swiss-Prot
    O94875
    Related
    ENSP00000321983.6, ENST00000319454.10
    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:532588
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:631691
    SH3; Src Homology 3 domain superfamily
  13. XM_017008770.2XP_016864259.1  sorbin and SH3 domain-containing protein 2 isoform X35

  14. XM_017008766.2XP_016864255.1  sorbin and SH3 domain-containing protein 2 isoform X32

    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:483539
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:582642
    SH3; Src Homology 3 domain superfamily
  15. XM_006714390.2XP_006714453.1  sorbin and SH3 domain-containing protein 2 isoform X28

    See identical proteins and their annotated locations for XP_006714453.1

    UniProtKB/Swiss-Prot
    O94875
    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:502558
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:601661
    SH3; Src Homology 3 domain superfamily
  16. XM_017008760.2XP_016864249.1  sorbin and SH3 domain-containing protein 2 isoform X22

  17. XM_017008769.2XP_016864258.1  sorbin and SH3 domain-containing protein 2 isoform X34

  18. XM_017008764.2XP_016864253.1  sorbin and SH3 domain-containing protein 2 isoform X31

  19. XM_005263310.2XP_005263367.1  sorbin and SH3 domain-containing protein 2 isoform X24

    Conserved Domains (3) summary
    smart00459
    Location:144194
    Sorb; Sorbin homologous domain
    cd11923
    Location:538594
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:637697
    SH3; Src Homology 3 domain superfamily
  20. XM_006714388.2XP_006714451.1  sorbin and SH3 domain-containing protein 2 isoform X21

    Conserved Domains (3) summary
    smart00459
    Location:144194
    Sorb; Sorbin homologous domain
    cd11923
    Location:563619
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:662722
    SH3; Src Homology 3 domain superfamily
  21. XM_005263313.2XP_005263370.1  sorbin and SH3 domain-containing protein 2 isoform X30

    Conserved Domains (3) summary
    smart00459
    Location:167212
    Sorb; Sorbin homologous domain
    cd11923
    Location:499555
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:598658
    SH3; Src Homology 3 domain superfamily
  22. XM_017008762.2XP_016864251.1  sorbin and SH3 domain-containing protein 2 isoform X27

  23. XM_005263311.2XP_005263368.1  sorbin and SH3 domain-containing protein 2 isoform X25

    Conserved Domains (3) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11923
    Location:533589
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:632692
    SH3; Src Homology 3 domain superfamily
  24. XM_005263308.2XP_005263365.1  sorbin and SH3 domain-containing protein 2 isoform X19

    Conserved Domains (3) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11923
    Location:586642
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:685745
    SH3; Src Homology 3 domain superfamily
  25. XM_005263307.2XP_005263364.1  sorbin and SH3 domain-containing protein 2 isoform X12

    Conserved Domains (4) summary
    smart00459
    Location:381431
    Sorb; Sorbin homologous domain
    cd11917
    Location:899959
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:800856
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:725779
    SH3; Src Homology 3 domain superfamily
  26. XM_017008754.2XP_016864243.1  sorbin and SH3 domain-containing protein 2 isoform X11

  27. XM_017008775.2XP_016864264.1  sorbin and SH3 domain-containing protein 2 isoform X39

  28. XM_017008753.2XP_016864242.1  sorbin and SH3 domain-containing protein 2 isoform X10

  29. XM_017008748.2XP_016864237.1  sorbin and SH3 domain-containing protein 2 isoform X5

  30. XM_024454257.1XP_024310025.1  sorbin and SH3 domain-containing protein 2 isoform X9

    Conserved Domains (5) summary
    smart00459
    Location:539589
    Sorb; Sorbin homologous domain
    cd11917
    Location:10041064
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:830884
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:905961
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl28144
    Location:622814
    Herpes_TK; Thymidine kinase from herpesvirus
  31. XM_017008752.2XP_016864241.1  sorbin and SH3 domain-containing protein 2 isoform X8

  32. XM_017008751.2XP_016864240.1  sorbin and SH3 domain-containing protein 2 isoform X7

  33. XM_017008750.2XP_016864239.1  sorbin and SH3 domain-containing protein 2 isoform X6

  34. XM_017008741.2XP_016864230.1  sorbin and SH3 domain-containing protein 2 isoform X2

  35. XM_017008767.2XP_016864256.1  sorbin and SH3 domain-containing protein 2 isoform X32

    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:483539
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:582642
    SH3; Src Homology 3 domain superfamily
  36. XM_017008765.2XP_016864254.1  sorbin and SH3 domain-containing protein 2 isoform X31

  37. XM_017008757.1XP_016864246.1  sorbin and SH3 domain-containing protein 2 isoform X17

  38. XM_017008774.2XP_016864263.1  sorbin and SH3 domain-containing protein 2 isoform X38

  39. XM_017008773.2XP_016864262.1  sorbin and SH3 domain-containing protein 2 isoform X37

  40. XM_017008740.2XP_016864229.1  sorbin and SH3 domain-containing protein 2 isoform X1

  41. XM_017008743.2XP_016864232.1  sorbin and SH3 domain-containing protein 2 isoform X3

  42. XM_017008744.2XP_016864233.1  sorbin and SH3 domain-containing protein 2 isoform X4

  43. XM_017008739.2XP_016864228.1  sorbin and SH3 domain-containing protein 2 isoform X1

  44. XM_017008738.2XP_016864227.1  sorbin and SH3 domain-containing protein 2 isoform X1

  45. XM_017008761.2XP_016864250.1  sorbin and SH3 domain-containing protein 2 isoform X23

RNA

  1. XR_002959769.1 RNA Sequence

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