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Sorbs2 sorbin and SH3 domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 234214, updated on 10-Jun-2024

Summary

Official Symbol
Sorbs2provided by MGI
Official Full Name
sorbin and SH3 domain containing 2provided by MGI
Primary source
MGI:MGI:1924574
See related
Ensembl:ENSMUSG00000031626 AllianceGenome:MGI:1924574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Argbp2; nArgBP2; mKIAA0777; A530071H08; 2010203O03Rik; 9430041O17Rik
Summary
Enables protein domain specific binding activity. Acts upstream of or within Notch signaling pathway; acetylcholine receptor signaling pathway; and regulation of skeletal muscle acetylcholine-gated channel clustering. Located in plasma membrane and synapse. Is expressed in several structures, including alimentary system; brain; cardiovascular system; cranium; and foot bone. Orthologous to human SORBS2 (sorbin and SH3 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in heart adult (RPKM 23.2), cortex adult (RPKM 14.3) and 17 other tissues See more
Orthologs
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Genomic context

See Sorbs2 in Genome Data Viewer
Location:
8 B1.1; 8 25.44 cM
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (45960470..46280943)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (45507788..45827906)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30504 Neighboring gene family with sequence similarity 149, member A Neighboring gene STARR-seq mESC enhancer starr_21371 Neighboring gene toll-like receptor 3 Neighboring gene predicted gene, 30759 Neighboring gene predicted gene 16351 Neighboring gene predicted gene, 23604 Neighboring gene predicted gene, 51529 Neighboring gene STARR-seq mESC enhancer starr_21373 Neighboring gene predicted gene, 30635 Neighboring gene sorbin and SH3 domain containing 2, opposite strand Neighboring gene predicted gene, 25309 Neighboring gene PDZ and LIM domain 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (5)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • 2010203O03Rik, 9430041O17Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sorbin and SH3 domain-containing protein 2
Names
Arg/Abl-binding protein 2
Arg/Abl-interacting protein ArgBP2
arg-binding protein 2
arg/Abl-interacting protein 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205219.1NP_001192148.1  sorbin and SH3 domain-containing protein 2 isoform 1

    See identical proteins and their annotated locations for NP_001192148.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC113469, AC116747, AC116861
    Consensus CDS
    CCDS57618.1
    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    UniProtKB/TrEMBL
    B9EKP8
    Related
    ENSMUSP00000128000.3, ENSMUST00000171337.10
    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11917
    Location:11541214
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:9801034
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10551111
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  2. NM_001310707.1NP_001297636.1  sorbin and SH3 domain-containing protein 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences but maintains the reading frame compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
    Source sequence(s)
    AC113469, AK041051, AK050951, AK083429, AK140498, BB609472, BC157944, BE862797, CN535874
    Consensus CDS
    CCDS80872.1
    UniProtKB/TrEMBL
    D3Z080
    Related
    ENSMUSP00000123250.2, ENSMUST00000132139.9
    Conserved Domains (3) summary
    smart00459
    Location:144194
    Sorb; Sorbin homologous domain
    cd11923
    Location:558614
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:483537
    SH3; Src Homology 3 domain superfamily
  3. NM_001310708.1NP_001297637.1  sorbin and SH3 domain-containing protein 2 isoform 4

    See identical proteins and their annotated locations for NP_001297637.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and has multiple coding region differences but maintains the reading frame compared to variant 1. It encodes isoform 4, which is shorter than isoform 1.
    Source sequence(s)
    AC113469, AC116747, BC157944, BE862797
    Consensus CDS
    CCDS80874.1
    UniProtKB/TrEMBL
    B2RXQ9
    Related
    ENSMUSP00000121619.2, ENSMUST00000130011.8
    Conserved Domains (4) summary
    cd11923
    Location:493549
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:232374
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam02208
    Location:116157
    Sorb; Sorbin homologous domain
    cl17036
    Location:592652
    SH3; Src Homology 3 domain superfamily
  4. NM_001402663.1NP_001389592.1  sorbin and SH3 domain-containing protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
  5. NM_001402664.1NP_001389593.1  sorbin and SH3 domain-containing protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747
  6. NM_001402665.1NP_001389594.1  sorbin and SH3 domain-containing protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747
  7. NM_001402666.1NP_001389595.1  sorbin and SH3 domain-containing protein 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  8. NM_001402667.1NP_001389596.1  sorbin and SH3 domain-containing protein 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  9. NM_001402668.1NP_001389597.1  sorbin and SH3 domain-containing protein 2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  10. NM_001402669.1NP_001389598.1  sorbin and SH3 domain-containing protein 2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  11. NM_001402670.1NP_001389599.1  sorbin and SH3 domain-containing protein 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747
    UniProtKB/TrEMBL
    A0A1L7NR37
  12. NM_001402671.1NP_001389600.1  sorbin and SH3 domain-containing protein 2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  13. NM_001402672.1NP_001389601.1  sorbin and SH3 domain-containing protein 2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC116861
  14. NM_001402673.1NP_001389602.1  sorbin and SH3 domain-containing protein 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
  15. NM_001402674.1NP_001389603.1  sorbin and SH3 domain-containing protein 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747, AC158351
    UniProtKB/TrEMBL
    A0A0R4J1W0
  16. NM_001402675.1NP_001389604.1  sorbin and SH3 domain-containing protein 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AC113469, AC116747
  17. NM_172752.4NP_766340.4  sorbin and SH3 domain-containing protein 2 isoform 2

    See identical proteins and their annotated locations for NP_766340.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC113469, AC116747, AC116861
    Consensus CDS
    CCDS57619.1
    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    UniProtKB/TrEMBL
    B7ZWM6, E9Q0B0
    Related
    ENSMUSP00000067641.8, ENSMUST00000067107.15
    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11917
    Location:11361196
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:9621016
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10371093
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    45960470..46280943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153896.1XP_036009789.1  sorbin and SH3 domain-containing protein 2 isoform X10

    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    Conserved Domains (4) summary
    cd11920
    Location:9951049
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10701126
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    pfam02208
    Location:147188
    Sorb; Sorbin homologous domain
    cl17036
    Location:11691219
    SH3; Src Homology 3 domain superfamily
  2. XM_030243439.2XP_030099299.1  sorbin and SH3 domain-containing protein 2 isoform X29

    Conserved Domains (3) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11923
    Location:582638
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:681741
    SH3; Src Homology 3 domain superfamily
  3. XM_036153910.1XP_036009803.1  sorbin and SH3 domain-containing protein 2 isoform X36

    Conserved Domains (3) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11923
    Location:509565
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:608668
    SH3; Src Homology 3 domain superfamily
  4. XM_036153905.1XP_036009798.1  sorbin and SH3 domain-containing protein 2 isoform X28

    Conserved Domains (3) summary
    smart00459
    Location:144194
    Sorb; Sorbin homologous domain
    cd11923
    Location:586642
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:685745
    SH3; Src Homology 3 domain superfamily
  5. XM_036153909.1XP_036009802.1  sorbin and SH3 domain-containing protein 2 isoform X35

    Conserved Domains (4) summary
    cd11923
    Location:524580
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:263405
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam02208
    Location:147188
    Sorb; Sorbin homologous domain
    cl17036
    Location:449503
    SH3; Src Homology 3 domain superfamily
  6. XM_036153911.1XP_036009804.1  sorbin and SH3 domain-containing protein 2 isoform X38

    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:479535
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:578638
    SH3; Src Homology 3 domain superfamily
  7. XM_017312696.2XP_017168185.1  sorbin and SH3 domain-containing protein 2 isoform X41

    Conserved Domains (3) summary
    smart00459
    Location:113163
    Sorb; Sorbin homologous domain
    cd11923
    Location:456512
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:555615
    SH3; Src Homology 3 domain superfamily
  8. XM_006509385.1XP_006509448.1  sorbin and SH3 domain-containing protein 2 isoform X39

    Related
    ENSMUSP00000118353.2, ENSMUST00000153798.8
    Conserved Domains (3) summary
    smart00459
    Location:136186
    Sorb; Sorbin homologous domain
    cd11923
    Location:478534
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:577637
    SH3; Src Homology 3 domain superfamily
  9. XM_036153912.1XP_036009805.1  sorbin and SH3 domain-containing protein 2 isoform X40

    UniProtKB/TrEMBL
    A0A0R4J1W0
    Related
    ENSMUSP00000121235.2, ENSMUST00000139869.8
    Conserved Domains (3) summary
    cd11923
    Location:464520
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    pfam02208
    Location:139180
    Sorb; Sorbin homologous domain
    cl17036
    Location:563623
    SH3; Src Homology 3 domain superfamily
  10. XM_011242198.1XP_011240500.1  sorbin and SH3 domain-containing protein 2 isoform X1

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11917
    Location:14411501
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:12671321
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:13421398
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  11. XM_011242200.1XP_011240502.1  sorbin and SH3 domain-containing protein 2 isoform X3

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11920
    Location:12671321
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:13421398
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:14411491
    SH3; Src Homology 3 domain superfamily
  12. XM_011242199.1XP_011240501.1  sorbin and SH3 domain-containing protein 2 isoform X2

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11917
    Location:14401500
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:12661320
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:13411397
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  13. XM_011242201.1XP_011240503.1  sorbin and SH3 domain-containing protein 2 isoform X4

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11920
    Location:12661320
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:13411397
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:14401490
    SH3; Src Homology 3 domain superfamily
  14. XM_036153897.1XP_036009790.1  sorbin and SH3 domain-containing protein 2 isoform X11

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11920
    Location:740794
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:815871
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:914974
    SH3; Src Homology 3 domain superfamily
  15. XM_011242205.1XP_011240507.1  sorbin and SH3 domain-containing protein 2 isoform X12

    Conserved Domains (3) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:814870
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:913973
    SH3; Src Homology 3 domain superfamily
  16. XM_030243433.1XP_030099293.1  sorbin and SH3 domain-containing protein 2 isoform X13

    Conserved Domains (3) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:814870
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:739793
    SH3; Src Homology 3 domain superfamily
  17. XM_011242206.1XP_011240508.1  sorbin and SH3 domain-containing protein 2 isoform X15

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:786842
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:543706
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:885945
    SH3; Src Homology 3 domain superfamily
  18. XM_030243435.1XP_030099295.1  sorbin and SH3 domain-containing protein 2 isoform X16

    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:786842
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:543706
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:711765
    SH3; Src Homology 3 domain superfamily
  19. XM_017312691.1XP_017168180.1  sorbin and SH3 domain-containing protein 2 isoform X17

    Conserved Domains (5) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11920
    Location:692746
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:767823
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:506648
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:866916
    SH3; Src Homology 3 domain superfamily
  20. XM_011242202.1XP_011240504.1  sorbin and SH3 domain-containing protein 2 isoform X5

    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    Conserved Domains (4) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11917
    Location:13401400
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:11661220
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:12411297
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  21. XM_030243437.1XP_030099297.1  sorbin and SH3 domain-containing protein 2 isoform X22

    Conserved Domains (3) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:715771
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:814874
    SH3; Src Homology 3 domain superfamily
  22. XM_030243438.1XP_030099298.1  sorbin and SH3 domain-containing protein 2 isoform X23

    Conserved Domains (3) summary
    smart00459
    Location:372422
    Sorb; Sorbin homologous domain
    cd11923
    Location:714770
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl17036
    Location:813873
    SH3; Src Homology 3 domain superfamily
  23. XM_036153903.1XP_036009796.1  sorbin and SH3 domain-containing protein 2 isoform X24

    Conserved Domains (4) summary
    cd11920
    Location:625679
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:700756
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    pfam02208
    Location:375416
    Sorb; Sorbin homologous domain
    cl17036
    Location:799859
    SH3; Src Homology 3 domain superfamily
  24. XM_036153895.1XP_036009788.1  sorbin and SH3 domain-containing protein 2 isoform X6

    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11917
    Location:12071267
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:10331087
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:11081164
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  25. XM_011242207.1XP_011240509.1  sorbin and SH3 domain-containing protein 2 isoform X25

    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11923
    Location:581637
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:345507
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:680740
    SH3; Src Homology 3 domain superfamily
  26. XM_011242204.1XP_011240506.1  sorbin and SH3 domain-containing protein 2 isoform X8

    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    Conserved Domains (4) summary
    smart00459
    Location:167217
    Sorb; Sorbin homologous domain
    cd11917
    Location:11351195
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:9611015
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10361092
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  27. XM_017312692.1XP_017168181.1  sorbin and SH3 domain-containing protein 2 isoform X27

    Conserved Domains (4) summary
    smart00459
    Location:167212
    Sorb; Sorbin homologous domain
    cd11923
    Location:547603
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:286428
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:646706
    SH3; Src Homology 3 domain superfamily
  28. XM_017312687.1XP_017168176.1  sorbin and SH3 domain-containing protein 2 isoform X7

    UniProtKB/Swiss-Prot
    Q3USC6, Q3UTJ2, Q80TS1, Q8BJL6, Q8BJU3, Q8BLW9, Q8BX47, Q8CHU0
    UniProtKB/TrEMBL
    A0A0S3CWK3
    Related
    ENSMUSP00000070720.8, ENSMUST00000067065.14
    Conserved Domains (4) summary
    smart00459
    Location:144189
    Sorb; Sorbin homologous domain
    cd11917
    Location:11971257
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11920
    Location:10231077
    SH3_Sorbs2_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:10981154
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
  29. XM_011242209.1XP_011240511.1  sorbin and SH3 domain-containing protein 2 isoform X31

    Conserved Domains (4) summary
    smart00459
    Location:144189
    Sorb; Sorbin homologous domain
    cd11923
    Location:524580
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    PHA03307
    Location:263405
    PHA03307; transcriptional regulator ICP4; Provisional
    cl17036
    Location:623683
    SH3; Src Homology 3 domain superfamily
  30. XM_030243443.1XP_030099303.1  sorbin and SH3 domain-containing protein 2 isoform X43

    Conserved Domains (3) summary
    cd11923
    Location:329385
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:436
    Sorb; Sorbin homologous domain
    cl17036
    Location:254308
    SH3; Src Homology 3 domain superfamily
  31. XM_006509387.1XP_006509450.1  sorbin and SH3 domain-containing protein 2 isoform X42

    Conserved Domains (3) summary
    cd11923
    Location:328384
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:436
    Sorb; Sorbin homologous domain
    cl17036
    Location:427487
    SH3; Src Homology 3 domain superfamily
  32. XM_030243444.1XP_030099304.1  sorbin and SH3 domain-containing protein 2 isoform X44

    Conserved Domains (3) summary
    cd11923
    Location:328384
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:436
    Sorb; Sorbin homologous domain
    cl17036
    Location:253307
    SH3; Src Homology 3 domain superfamily
  33. XM_006509375.1XP_006509438.1  sorbin and SH3 domain-containing protein 2 isoform X14

    UniProtKB/TrEMBL
    Z4YJR7
    Conserved Domains (4) summary
    cd11917
    Location:939999
    SH3_Sorbs2_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cd11923
    Location:840896
    SH3_Sorbs2_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 2 (Sorbs2), also called Arg-binding protein 2 (ArgBP2)
    cl02617
    Location:431
    Sorb; Sorbin homologous domain
    cl17036
    Location:765819
    SH3; Src Homology 3 domain superfamily