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ZNF726 zinc finger protein 726 [ Homo sapiens (human) ]

Gene ID: 730087, updated on 23-Nov-2021

Summary

Official Symbol
ZNF726provided by HGNC
Official Full Name
zinc finger protein 726provided by HGNC
Primary source
HGNC:HGNC:32462
See related
Ensembl:ENSG00000213967
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF92P3
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See ZNF726 in Genome Data Viewer
Location:
19p12
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (23914886..23944714)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (24097688..24127516)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein SA pseudogene 58 Neighboring gene BCL2 interacting protein 3 pseudogene 39 Neighboring gene zinc finger protein 726 pseudogene 1 Neighboring gene uncharacterized LOC100505851 Neighboring gene RNA, 28S ribosomal pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 726
Names
zinc finger protein 92 pseudogene 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244038.2NP_001230967.1  zinc finger protein 726 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC011503, CN359557
    Consensus CDS
    CCDS59372.1
    UniProtKB/Swiss-Prot
    A6NNF4
    Related
    ENSP00000471516.1, ENST00000594466.6
    Conserved Domains (5) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:186612
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:371391
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:524548
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001348687.2NP_001335616.1  zinc finger protein 726 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AB593087, AC011503, CN359557
    Consensus CDS
    CCDS86738.1
    UniProtKB/TrEMBL
    F1T0F3
    Related
    ENSP00000461349.1, ENST00000575986.1
    Conserved Domains (1) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
  3. NM_001348688.2NP_001335617.1  zinc finger protein 726 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC011503
    Consensus CDS
    CCDS54241.1
    UniProtKB/TrEMBL
    E9PLI7
    Related
    ENSP00000433319.2, ENST00000525354.6
    Conserved Domains (1) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
  4. NM_001348689.2NP_001335618.1  zinc finger protein 726 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (4) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC011503
    Consensus CDS
    CCDS86739.1
    UniProtKB/Swiss-Prot
    A6NNF4
    Related
    ENSP00000432583.2, ENST00000531821.6
    Conserved Domains (1) summary
    smart00349
    Location:464
    KRAB; krueppel associated box

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    23914886..23944714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001190829.1: Suppressed sequence

    Description
    NM_001190829.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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