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Zfp787 zinc finger protein 787 [ Mus musculus (house mouse) ]

Gene ID: 67109, updated on 18-Sep-2024

Summary

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Official Symbol
Zfp787provided by MGI
Official Full Name
zinc finger protein 787provided by MGI
Primary source
MGI:MGI:1914359
See related
Ensembl:ENSMUSG00000046792 AllianceGenome:MGI:1914359
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf787; 2210018M03Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in male reproductive system and urinary system. Orthologous to human ZNF787 (zinc finger protein 787). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 27.5), adrenal adult (RPKM 22.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp787 in Genome Data Viewer
Location:
7 A1; 7 3.55 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6134488..6162382, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6131489..6159380, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene NLR family, pyrin domain containing 4C Neighboring gene predicted gene, 18758 Neighboring gene STARR-positive B cell enhancer ABC_E9284 Neighboring gene predicted gene, 36371 Neighboring gene STARR-positive B cell enhancer ABC_E4893 Neighboring gene zinc finger protein 444 Neighboring gene STARR-seq mESC enhancer starr_17966 Neighboring gene galanin-like peptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comprehensive interactome of Otx2 in the adult mouse neural retina. Fant B, et al. Genesis, 2015 Nov. PMID 26426291
  2. Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain. Lee Y, et al. Biochem Biophys Res Commun, 2020 Aug 13. PMID 32560809
  3. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 787

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013012.2 → NP_001013030.1  zinc finger protein 787 isoform a

    See identical proteins and their annotated locations for NP_001013030.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 1, encodes the longer isoform (a).
    Source sequence(s)
    AC026949
    Consensus CDS
    CCDS20769.1
    UniProtKB/Swiss-Prot
    B9EHE2, Q8BIF9
    Related
    ENSMUSP00000092468.2, ENSMUST00000094870.3
    Conserved Domains (3) summary
    COG5048
    Location:93 → 200
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:66 → 88
    zf-C2H2; Zinc finger, C2H2 type

  2. NM_001379298.1 → NP_001366227.1  zinc finger protein 787 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 3, encodes isoform b.
    Source sequence(s)
    AC026949
    Conserved Domains (3) summary
    COG5048
    Location:62 → 169
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:37 → 57
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:35 → 57
    zf-C2H2; Zinc finger, C2H2 type

  3. NM_001379299.1 → NP_001366228.1  zinc finger protein 787 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variant 4, encodes isoform b.
    Source sequence(s)
    AC026949
    Conserved Domains (3) summary
    COG5048
    Location:62 → 169
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:37 → 57
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:35 → 57
    zf-C2H2; Zinc finger, C2H2 type

  4. NM_001379300.1 → NP_001366229.1  zinc finger protein 787 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variant 2, encodes the longer isoform (a).
    Source sequence(s)
    AC026949
    UniProtKB/Swiss-Prot
    B9EHE2, Q8BIF9
    Conserved Domains (3) summary
    COG5048
    Location:93 → 200
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:66 → 88
    zf-C2H2; Zinc finger, C2H2 type

RNA

  1. NR_166603.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026949

  2. NR_166604.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026949

  3. NR_166605.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026949

  4. NR_166606.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026949
    Related
    ENSMUST00000207628.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    6134488..6162382 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540313.5 → XP_006540376.1  zinc finger protein 787 isoform X1

    See identical proteins and their annotated locations for XP_006540376.1

    UniProtKB/Swiss-Prot
    B9EHE2, Q8BIF9
    Conserved Domains (3) summary
    COG5048
    Location:93 → 200
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:68 → 88
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:66 → 88
    zf-C2H2; Zinc finger, C2H2 type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BIF9.3 GenPept UniProtKB/Swiss-Prot:Q8BIF9

Gene LinkOut

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