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ZNF787 zinc finger protein 787 [ Homo sapiens (human) ]

Gene ID: 126208, updated on 2-Nov-2024

Summary

Official Symbol
ZNF787provided by HGNC
Official Full Name
zinc finger protein 787provided by HGNC
Primary source
HGNC:HGNC:26998
See related
Ensembl:ENSG00000142409 AllianceGenome:HGNC:26998
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TIP20
Summary
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in colon (RPKM 5.0), spleen (RPKM 4.4) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF787 in Genome Data Viewer
Location:
19q13.43
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56087366..56121295, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59186221..59220132, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56598732..56632664, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene NLR family pyrin domain containing 5 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56537936-56539135 Neighboring gene long intergenic non-protein coding RNA 1864 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11062 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15111 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11063 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56596377-56596878 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56596879-56597378 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:56597714-56598313 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_51805 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr19:56602588-56603787 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15112 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:56622697-56623374 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15113 Neighboring gene uncharacterized LOC124904773 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56626767-56627443 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56628849-56629564 Neighboring gene Sharpr-MPRA regulatory region 1998 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:56632431-56633146 Neighboring gene uncharacterized LOC124904772 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_51865 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56640200-56640700 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:56640701-56641201 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_51899 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15114 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15115 Neighboring gene zinc finger protein 444

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger protein 787
Names
TTF-I-interacting peptide 20
transcription termination factor I interacting peptide 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054921.1 RefSeqGene

    Range
    5079..39008
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001002836.4NP_001002836.2  zinc finger protein 787 isoform 1

    See identical proteins and their annotated locations for NP_001002836.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC024580, AI037960, BC077728, KF573663
    Consensus CDS
    CCDS42634.1
    UniProtKB/Swiss-Prot
    A0A087WUD1, O00455, Q6DD87
    Related
    ENSP00000478557.1, ENST00000610935.2
    Conserved Domains (2) summary
    COG5048
    Location:67200
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:6888
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001351682.2NP_001338611.1  zinc finger protein 787 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC024580, BC037737, HY059733
    Consensus CDS
    CCDS86810.1
    UniProtKB/TrEMBL
    K7EKJ5
    Related
    ENSP00000465647.1, ENST00000587279.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    56087366..56121295 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438164.1XP_047294120.1  zinc finger protein 787 isoform X1

    UniProtKB/Swiss-Prot
    A0A087WUD1, O00455, Q6DD87

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    59186221..59220132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)