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RPS6KA4 ribosomal protein S6 kinase A4 [ Canis lupus familiaris (dog) ]

Gene ID: 612105, updated on 17-Aug-2024

Summary

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Official Symbol
RPS6KA4provided by VGNC
Official Full Name
ribosomal protein S6 kinase A4provided by VGNC
Primary source
VGNC:VGNC:45741
See related
Ensembl:ENSCAFG00845030464
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (53754117..53765835, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (51315988..51327703, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (53216562..53228276, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (52846187..52857903, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (52432778..52444472, complement)

Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 12 Neighboring gene solute carrier family 22 member 11 Neighboring gene coiled-coil domain containing 88B Neighboring gene tRNA methyltransferase activator subunit 11-2 Neighboring gene peroxiredoxin 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ribosomal protein S6 kinase alpha-4
XP_022261454.1
XP_022261455.1
XP_022261456.1
XP_038281081.1
XP_038281082.1
XP_038281083.1
XP_038281084.1
XP_038281085.1
XP_038281086.1
XP_038310135.1
XP_038310136.1
XP_038357341.1
XP_038357342.1
XP_038357343.1
XP_038357344.1
XP_038357345.1
XP_038357346.1
XP_038420027.1
XP_038420028.1
XP_038420029.1
XP_038420030.1
XP_038420031.1
XP_038420032.1
XP_038484170.1
XP_038484171.1
XP_038484172.1
XP_038484173.1
XP_038484174.1
XP_038484175.1
XP_854926.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051822.1 Reference ROS_Cfam_1.0

    Range
    53754117..53765835 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038425157.1 → XP_038281085.1  ribosomal protein S6 kinase alpha-4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:364 → 674
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038425154.1 → XP_038281082.1  ribosomal protein S6 kinase alpha-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:409 → 719
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038425153.1 → XP_038281081.1  ribosomal protein S6 kinase alpha-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Related
    ENSCAFP00845042472.1, ENSCAFT00845054067.1
    Conserved Domains (1) summary
    cl21453
    Location:32 → 396
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038425158.1 → XP_038281086.1  ribosomal protein S6 kinase alpha-4 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:332 → 642
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038425156.1 → XP_038281084.1  ribosomal protein S6 kinase alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:1 → 333
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038425155.1 → XP_038281083.1  ribosomal protein S6 kinase alpha-4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ36, A0A8C0RIW5, A0A8I3Q480, A0A8I3Q6K1, A0A8P0NXZ7
    Related
    ENSCAFP00845042457.1, ENSCAFT00845054049.1
    Conserved Domains (1) summary
    cl21453
    Location:32 → 364
    PKc_like; Protein Kinases, catalytic domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049278.1 Alternate UMICH_Zoey_3.1

    Range
    52846187..52857903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038501417.1 → XP_038357345.1  ribosomal protein S6 kinase alpha-4 isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:364 → 674
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038501414.1 → XP_038357342.1  ribosomal protein S6 kinase alpha-4 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:409 → 719
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038501413.1 → XP_038357341.1  ribosomal protein S6 kinase alpha-4 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:32 → 396
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038501418.1 → XP_038357346.1  ribosomal protein S6 kinase alpha-4 isoform X6

    Conserved Domains (1) summary
    cl21453
    Location:332 → 642
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038501416.1 → XP_038357344.1  ribosomal protein S6 kinase alpha-4 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 333
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038501415.1 → XP_038357343.1  ribosomal protein S6 kinase alpha-4 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:32 → 364
    PKc_like; Protein Kinases, catalytic domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

    Range
    52432778..52444472 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038628246.1 → XP_038484174.1  ribosomal protein S6 kinase alpha-4 isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:364 → 674
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038628243.1 → XP_038484171.1  ribosomal protein S6 kinase alpha-4 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:409 → 719
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038628242.1 → XP_038484170.1  ribosomal protein S6 kinase alpha-4 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:32 → 396
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038628247.1 → XP_038484175.1  ribosomal protein S6 kinase alpha-4 isoform X6

    Conserved Domains (1) summary
    cl21453
    Location:332 → 642
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038628245.1 → XP_038484173.1  ribosomal protein S6 kinase alpha-4 isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:1 → 333
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038628244.1 → XP_038484172.1  ribosomal protein S6 kinase alpha-4 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:32 → 364
    PKc_like; Protein Kinases, catalytic domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

    Range
    53216562..53228276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038564103.1 → XP_038420031.1  ribosomal protein S6 kinase alpha-4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:364 → 674
    PKc_like; Protein Kinases, catalytic domain

  2. XM_038564100.1 → XP_038420028.1  ribosomal protein S6 kinase alpha-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:409 → 719
    PKc_like; Protein Kinases, catalytic domain

  3. XM_038564099.1 → XP_038420027.1  ribosomal protein S6 kinase alpha-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:32 → 396
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038564104.1 → XP_038420032.1  ribosomal protein S6 kinase alpha-4 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:332 → 642
    PKc_like; Protein Kinases, catalytic domain

  5. XM_038564102.1 → XP_038420030.1  ribosomal protein S6 kinase alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:1 → 333
    PKc_like; Protein Kinases, catalytic domain

  6. XM_038564101.1 → XP_038420029.1  ribosomal protein S6 kinase alpha-4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ36, A0A8C0RIW5, A0A8I3Q480, A0A8I3Q6K1, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:32 → 364
    PKc_like; Protein Kinases, catalytic domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51315988..51327703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038454207.1 → XP_038310135.1  ribosomal protein S6 kinase alpha-4 isoform X5

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:364 → 674
    PKc_like; Protein Kinases, catalytic domain

  2. XM_022405747.2 → XP_022261455.1  ribosomal protein S6 kinase alpha-4 isoform X2

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:409 → 719
    PKc_like; Protein Kinases, catalytic domain

  3. XM_022405746.2 → XP_022261454.1  ribosomal protein S6 kinase alpha-4 isoform X1

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:32 → 396
    PKc_like; Protein Kinases, catalytic domain

  4. XM_038454208.1 → XP_038310136.1  ribosomal protein S6 kinase alpha-4 isoform X6

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:332 → 642
    PKc_like; Protein Kinases, catalytic domain

  5. XM_022405748.2 → XP_022261456.1  ribosomal protein S6 kinase alpha-4 isoform X4

    UniProtKB/TrEMBL
    A0A8I3Q480, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:1 → 333
    PKc_like; Protein Kinases, catalytic domain

  6. XM_849833.6 → XP_854926.1  ribosomal protein S6 kinase alpha-4 isoform X3

    UniProtKB/TrEMBL
    A0A8C0KQ36, A0A8C0RIW5, A0A8I3Q480, A0A8I3Q6K1, A0A8P0NXZ7
    Conserved Domains (1) summary
    cl21453
    Location:32 → 364
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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