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IGSF9 immunoglobulin superfamily member 9 [ Homo sapiens (human) ]

Gene ID: 57549, updated on 21-Dec-2019

Summary

Official Symbol
IGSF9provided by HGNC
Official Full Name
immunoglobulin superfamily member 9provided by HGNC
Primary source
HGNC:HGNC:18132
See related
Ensembl:ENSG00000085552 MIM:609738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Nrt1; IGSF9A; FP18798
Expression
Biased expression in skin (RPKM 12.2), stomach (RPKM 7.5) and 8 other tissues See more
Orthologs

Genomic context

See IGSF9 in Genome Data Viewer
Location:
1q23.2
Exon count:
22
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (159927041..159945661, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (159896829..159915386, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 45 Neighboring gene microRNA 4259 Neighboring gene transgelin 2 Neighboring gene SLAM family member 9 Neighboring gene long intergenic non-protein coding RNA 1133 Neighboring gene Fc receptor like 6 pseudogene 1 Neighboring gene ribosomal protein L27a pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • KIAA1355

Gene Ontology Provided by GOA

Function Evidence Code Pubs
cell-cell adhesion mediator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite development IEA
Inferred from Electronic Annotation
more info
 
dendrite self-avoidance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
homophilic cell adhesion via plasma membrane adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of synapse organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
inhibitory synapse IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein turtle homolog A
Names
immunoglobulin superfamily member 9A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135050.2NP_001128522.1  protein turtle homolog A isoform a precursor

    See identical proteins and their annotated locations for NP_001128522.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AB037776, AI758999, AL513485, CK299326
    Consensus CDS
    CCDS44254.1
    UniProtKB/Swiss-Prot
    Q9P2J2
    Related
    ENSP00000357073.1, ENST00000368094.6
    Conserved Domains (7) summary
    cd00096
    Location:154220
    Ig; Immunoglobulin domain
    smart00410
    Location:233319
    IG_like; Immunoglobulin like
    cd00063
    Location:625715
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:136223
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:511596
    fn3; Fibronectin type III domain
    pfam13927
    Location:226305
    Ig_3; Immunoglobulin domain
    cl11960
    Location:341404
    Ig; Immunoglobulin domain
  2. NM_020789.4NP_065840.2  protein turtle homolog A isoform b precursor

    See identical proteins and their annotated locations for NP_065840.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AB037776, AI758999, AL513485, BC030141, CK299326
    Consensus CDS
    CCDS1190.1
    UniProtKB/Swiss-Prot
    Q9P2J2
    Related
    ENSP00000355049.3, ENST00000361509.7
    Conserved Domains (7) summary
    cd00096
    Location:154220
    Ig; Immunoglobulin domain
    smart00410
    Location:233319
    IG_like; Immunoglobulin like
    cd00063
    Location:609699
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:136223
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:495580
    fn3; Fibronectin type III domain
    pfam13927
    Location:226305
    Ig_3; Immunoglobulin domain
    cl11960
    Location:325388
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    159927041..159945661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017001884.1XP_016857373.1  protein turtle homolog A isoform X1

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