1BIH,1G1C,1FYT,1E0O,1EV2,1DGI,1DGI,1IRA,1IRA,1IRA,1CS6,1CS6,1CS6,1CS6,1DQT,1EPF,1F58,1F6A,1G0X,1GL4,1GXE,1HCF,1L6Z,1NCT,1NEU,1OLZ,1OVZ,1PKO,1QZ1,1XED,1Z9M,2C5D,2C5D,2CKN,2CRY,2IF7,2IFG,2V9Q,2DF3,2V9Q,1E4K,1Z7Z,2CQV,1ADQ,1BIH,1BIH,1BIH,1CDI,1E07,1E07,1FYT,1GSM,1HDM,1HXM,1I85,1I8L,1IJ9,1KOA,1N26,1NBQ,1NBQ,1NFD,1OW0,1PD6,1PY4,1Q8M,1RHF,1RHH,1S9V,1T0P,1TLK,1U2H,1YA5,1YA5,1ZVO,2ADG,2AVG,2AW2,2BK8,2FBO,2FRG,2GY5,2ICC,2IEP,2IEP,2ILL,2J12,2OR7,2OTU,2OYP,2V5S,2ID5,2DM3,2YR3,2EDJ,2DM2,2V5S,2EO9,1O0V,1EV2,2PKD,1L6Z,1HKF,1FYT,1O0V,1O0V,1O0V,1HDM,1S9V,1F6A,1HXM,1ZVO,1E4K,1HZH,1I1A,1XZ0,1A1M,1B2W,1RHH,1ZAG,1ZVO,1AQK,1JE6,1DR9,1F58,2FBJ,2IG2,1RHH,1IGA,2BC4,1A6A,1P4L,1HXM,2COQ,2ATP,1NFD,2UV3,1NFD,1NPU,1SQ2,1VES,1RHH,1QLR,2C1O,1ZV5,2IG2,1YPZ,1MI5,2NW2,2P5E,1TVD,1KTK,2Z35,2EYR,2IAL,1BD2,1ZGL,1D9K,2EYR,1OGA,1BWM,1J8H,2ESV,2AK4,1AO7,1OGA,1YMM,2ESV,1LIL,1DL7,1CD0,1AQK,2OM5,2OM5,1WWC,1HE7,2IFG,1P6F,2D3V,1OLL,1M4K,1URL,1PKQ,1IE5,2OCW,1ZOX,2OCW,2OCW,2OCW,2Q87,2NMS,1AKJ,1I8L,1AH1,1E07,1E07,2GK2,2DRU,1Z2K,1QA9,1HNG,2ILL,1WIT,1RHF,1P6F,1OLL,2GI7,2D3V,2FCB,2FCB,1F2Q,1IJ9,1ZXQ,1IGA,2ATP,2ARJ,1XIW,1XIW,1YPZ,1NFD,1N5A,1NFD,1KB5,1MI5,1OW0,2ZJS,1IQD,2V9T,3D5O,3D5O,2OM5,2E9W,2V44,2VRA,2OM5,2VA4,1CVS,1RY7,2R15,1JL4,1RZJ,1WIO,1WIO,1WIO,2ADG,1QLR,1IQD,1LIL,1NFD,1HXM


Conserved Protein Domain Family
Ig

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cd00096: Ig (this model, PSSM-Id:143165 is obsolete and has been replaced by 319273)
Click on image for an interactive view with Cn3D
Immunoglobulin domain
Ig: immunoglobulin (Ig) domain found in the Ig superfamily. The Ig superfamily is a heterogenous group of proteins, built on a common fold comprised of a sandwich of two beta sheets. Members of this group are components of immunoglobulin, neuroglia, cell surface glycoproteins, such as, T-cell receptors, CD2, CD4, CD8, and membrane glycoproteins, such as, butyrophilin and chondroitin sulfate proteoglycan core protein. A predominant feature of most Ig domains is a disulfide bridge connecting the two beta-sheets with a tryptophan residue packed against the disulfide bond.
Statistics
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PSSM-Id: 143165
View PSSM: cd00096
Aligned: 1833 rows
Threshold Bit Score: 26.6831
Threshold Setting Gi: 11514259
Created: 1-Nov-2000
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1BIH_A       230 TMIYCmygs------npmgYPNYFkngkdvngnpe------------------dritrhnrtsgKRLLFkttlp--edeg 283
gi 118101955  46 ATISCrvkn------sddsVIQLLnpnrqtiyfrdfrpl-----------kdsrfqlvnfsnseLRVSLtnvsi--sdeg 106
gi 148230168  44 AIISCrvkn------nddsVIQLLnpnrqtiyfrdvrpl-----------kdsrfqlvnfssneLRVSLsnvtl--edeg 104
gi 124100    328 VTVKCeah--------ggaQVVLLnstsprppts---------------------qgtsprpptSQIQFtlnaspedhkr 378
gi 66773952  421 VTVSCevpnvy---psdrlEIELFkgetiiesksfl----------------edmdkksletksLEMTFiptte--dtgk 479
gi 16798309  146 VGNSClatdf-----tkhnEFNITdspfletsavr-------------------ysgqsyyssfKFSSNdc-------ke 194
gi 115527968  60 ATISCqvnk------sddsVIQLLnpnrqtiyfrdfrpl-----------kdsrfqllnfssseLKVSLtnvsi--sdeg 120
gi 158538880  60 AIISCrvkn------nddsVIQLLnpnrqtiyfrdvrpl-----------kdsrfqlvnfsdneLLVSLsnvsl--sdeg 120
1WIO_A       194 VEFSFplaftv---ekltgSGELWwqaerassskswitfdlknkevsvkrvtqdpklqmgkklpLHLTLpqalp--qyag 268
gi 149212630 227 VRFSFplnlndqelnreqpNGELRwnmegtaspqvvkfswksd---sltrgtdappfnrdpkfpLTITLssvsp--shag 301
                         90       100
                 ....*....|....*....|....
1BIH_A       284 VYTCEVdngv-----gkpqKHSLK 302
gi 118101955 107 RYFCQLytd-------ppqEIYTT 123
gi 148230168 105 RYLCQLytd-------ppqEAFTT 121
gi 124100    379 RFFCSAalevd---gkslfKNQTL 399
gi 66773952  480 VLVCLAklhide-mefepkQRQST 502
gi 16798309  195 TGVCSSsgggtdlerdekvNFLSL 218
gi 115527968 121 RYFCQLytd-------ppqESYTT 137
gi 158538880 121 RYVCQLytd-------ppqEAYAD 137
1WIO_A       269 SGNLTLaleak----tgklHQEVN 288
gi 149212630 302 SGVFLLqfss------gtvEQKVN 319
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