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zbtb25 zinc finger and BTB domain containing 25 [ Danio rerio (zebrafish) ]

Gene ID: 567401, updated on 12-Sep-2024

Summary

Official Symbol
zbtb25provided by ZNC
Official Full Name
zinc finger and BTB domain containing 25provided by ZNC
Primary source
ZFIN:ZDB-GENE-041001-125
See related
Ensembl:ENSDARG00000042383 AllianceGenome:ZFIN:ZDB-GENE-041001-125
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-1h6.2
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleoplasm. Orthologous to human ZBTB25 (zinc finger and BTB domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (27705261..27712028, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (27808645..27812812, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase Neighboring gene si:dkey-1h6.8 Neighboring gene zinc finger and BTB domain containing 1 Neighboring gene zgc:153157

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    27705261..27712028 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_690696.6XP_695788.1  zinc finger and BTB domain-containing protein 25 isoform X2

    See identical proteins and their annotated locations for XP_695788.1

    UniProtKB/TrEMBL
    A0A8M9PD88, F1Q574, Q5RIH3
    Related
    ENSDARP00000115542.2, ENSDART00000139637.3
    Conserved Domains (1) summary
    pfam00651
    Location:14101
    BTB; BTB/POZ domain
  2. XM_017352734.3XP_017208223.1  zinc finger and BTB domain-containing protein 25 isoform X1

    UniProtKB/TrEMBL
    A0A8M6YV15
    Conserved Domains (1) summary
    pfam00651
    Location:39126
    BTB; BTB/POZ domain

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395075.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    132174..138941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473377.2XP_021329052.1  zinc finger and BTB domain-containing protein 25 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PD88, F1Q574, Q5RIH3
    Conserved Domains (1) summary
    pfam00651
    Location:14101
    BTB; BTB/POZ domain
  2. XM_021473376.2XP_021329051.1  zinc finger and BTB domain-containing protein 25 isoform X1

    UniProtKB/TrEMBL
    A0A8M6YV15
    Conserved Domains (1) summary
    pfam00651
    Location:39126
    BTB; BTB/POZ domain