U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mtor mechanistic target of rapamycin kinase [ Mus musculus (house mouse) ]

Gene ID: 56717, updated on 20-May-2024

Summary

Official Symbol
Mtorprovided by MGI
Official Full Name
mechanistic target of rapamycin kinaseprovided by MGI
Primary source
MGI:MGI:1928394
See related
Ensembl:ENSMUSG00000028991 AllianceGenome:MGI:1928394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FRAP; flat; FRAP2; Frap1; RAFT1; RAPT1; 2610315D21Rik
Summary
Enables protein serine/threonine kinase activity and ribosome binding activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; T-helper 1 cell lineage commitment; and neuronal action potential. Acts upstream of or within several processes, including heart development; positive regulation of cellular component biogenesis; and regulation of protein phosphorylation. Located in cytosol; dendrite; and nucleus. Part of TORC1 complex. Colocalizes with PML body. Is expressed in central nervous system; early conceptus; oocyte; respiratory system; and retina. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; kidney angiomyolipoma; lung disease (multiple); prostate cancer; and type 2 diabetes mellitus. Orthologous to human MTOR (mechanistic target of rapamycin kinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 23.0), kidney adult (RPKM 12.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Mtor in Genome Data Viewer
Location:
4 E2; 4 78.76 cM
Exon count:
58
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (148533039..148642142)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (148448582..148557685)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene dispatched RND transporter family member 3 Neighboring gene STARR-positive B cell enhancer ABC_E103 Neighboring gene UbiA prenyltransferase domain containing 1 Neighboring gene predicted gene, 23303 Neighboring gene angiopoietin-like 7 Neighboring gene STARR-positive B cell enhancer ABC_E1668 Neighboring gene predicted gene, 24002 Neighboring gene predicted gene, 23318 Neighboring gene exosome component 10 Neighboring gene spermidine synthase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
flat-top
GeneReviews: Not available

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC118056

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase III type 1 promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase III type 2 promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase III type 3 promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables TFIIIC-class transcription factor complex binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding IEA
Inferred from Electronic Annotation
more info
 
enables ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in 'de novo' pyrimidine nucleobase biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in DNA damage response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in T-helper 1 cell lineage commitment IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in TOR signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in TOR signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in TOR signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in TORC1 signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within TORC1 signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in TORC1 signaling ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within TORC2 signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in behavioral response to pain IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of calcineurin-NFAT signaling cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cardiac cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cardiac muscle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cardiac muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cardiac muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell projection organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell projection organization ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in cellular response to L-leucine ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to amino acid starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to amino acid stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to hypoxia IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to hypoxia NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cellular response to insulin stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to leucine starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to nutrient ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to nutrient levels IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to nutrient levels ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to nutrient levels NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cellular response to osmotic stress NAS
Non-traceable Author Statement
more info
PubMed 
involved_in cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in cytoskeleton organization NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within energy reserve metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within germ cell development IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within heart morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within heart valve morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in inflammatory response IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in long-term memory ISO
Inferred from Sequence Orthology
more info
 
involved_in lysosome organization ISO
Inferred from Sequence Orthology
more info
 
involved_in mRNA stabilization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in maternal process involved in female pregnancy ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within multicellular organism growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process NAS
Non-traceable Author Statement
more info
PubMed 
involved_in negative regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of autophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of autophagy NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within negative regulation of calcineurin-NFAT signaling cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of cell size IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within negative regulation of cell size ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in negative regulation of cholangiocyte apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of iodide transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of lysosome organization ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of macroautophagy IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of macroautophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of macroautophagy ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in negative regulation of muscle atrophy ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein localization to nucleus ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
involved_in neuronal action potential IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nucleus localization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of oligodendrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-serine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within peptidyl-serine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-serine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within peptidyl-threonine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within phosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of actin filament polymerization IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell growth NAS
Non-traceable Author Statement
more info
PubMed 
involved_in positive regulation of cell growth involved in cardiac muscle cell development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cellular senescence ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cholangiocyte proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of dendritic spine development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of eating behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of epithelial cell apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glycolytic process NAS
Non-traceable Author Statement
more info
PubMed 
involved_in positive regulation of granulosa cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of keratinocyte migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of lamellipodium assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of lipid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of lipid biosynthetic process NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within positive regulation of myotube differentiation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in positive regulation of neurogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron maturation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of oligodendrocyte differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of oligodendrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of pentose-phosphate shunt NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within positive regulation of peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of_or_within positive regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of skeletal muscle hypertrophy ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of stress fiber assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of translation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of translational initiation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of wound healing, spreading of epidermal cells ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
acts_upstream_of protein destabilization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein phosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of GTPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of autophagy IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of brown fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of carbohydrate metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of carbohydrate utilization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell size ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of fatty acid beta-oxidation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of glycogen biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of membrane permeability IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of osteoclast differentiation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of protein kinase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within regulation of protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of response to food ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of translation at synapse, modulating synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within response to amino acid IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to amino acid ISO
Inferred from Sequence Orthology
more info
 
involved_in response to cocaine ISO
Inferred from Sequence Orthology
more info
 
involved_in response to heat IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within response to insulin IDA
Inferred from Direct Assay
more info
PubMed 
involved_in response to nutrient ISO
Inferred from Sequence Orthology
more info
 
involved_in response to nutrient levels ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within rhythmic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ruffle organization IDA
Inferred from Direct Assay
more info
PubMed 
involved_in social behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in spinal cord development ISO
Inferred from Sequence Orthology
more info
 
involved_in visual learning ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within voluntary musculoskeletal movement IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with PML body IDA
Inferred from Direct Assay
more info
PubMed 
part_of TORC1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TORC1 complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of TORC1 complex ISO
Inferred from Sequence Orthology
more info
PubMed 
part_of TORC2 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of TORC2 complex ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in endomembrane system ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in phagocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase mTOR
Names
FK506 binding protein 12-rapamycin associated protein 1
FK506-binding protein 12-rapamycin complex-associated protein 1
FKBP-rapamycin associated protein (FRAP)
FKBP12-rapamycin complex-associated protein
angiopoietin-like factor CDT6
mammalian target of rapamycin
mechanistic target of rapamycin (serine/threonine kinase)
rapamycin target protein 1
NP_064393.2
XP_006539140.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020009.2NP_064393.2  serine/threonine-protein kinase mTOR

    See identical proteins and their annotated locations for NP_064393.2

    Status: VALIDATED

    Source sequence(s)
    BC112904, CJ130100
    Consensus CDS
    CCDS18937.1
    UniProtKB/Swiss-Prot
    Q2KHT0, Q811J5, Q9CST1, Q9JLN9
    Related
    ENSMUSP00000099510.4, ENSMUST00000103221.10
    Conserved Domains (6) summary
    COG5032
    Location:3632549
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd05169
    Location:21532431
    PIKKc_TOR; Catalytic domain of Target of Rapamycin
    pfam02260
    Location:25182549
    FATC; FATC domain
    pfam08771
    Location:20152112
    Rapamycin_bind; Rapamycin binding domain
    pfam11865
    Location:8541024
    DUF3385; Domain of unknown function (DUF3385)
    sd00044
    Location:655681
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    148533039..148642142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539077.3XP_006539140.1  serine/threonine-protein kinase mTOR isoform X1

    Conserved Domains (2) summary
    COG5032
    Location:21829
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    sd00044
    Location:235261
    HEAT; HEAT repeat [structural motif]