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ZNF280C zinc finger protein 280C [ Homo sapiens (human) ]

Gene ID: 55609, updated on 8-Dec-2019

Summary

Official Symbol
ZNF280Cprovided by HGNC
Official Full Name
zinc finger protein 280Cprovided by HGNC
Primary source
HGNC:HGNC:25955
See related
Ensembl:ENSG00000056277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZPET; SUHW3; ZNF633
Summary
This gene encodes a member of the zinc finger domain-containing protein family. This family member contains multiple Cys2-His2(C2H2)-type zinc finger domains, the most common type of zinc finger domain that self-folds to form a beta-beta-alpha structure that binds a zinc ion. [provided by RefSeq, Aug 2011]
Expression
Broad expression in testis (RPKM 6.8), endometrium (RPKM 1.7) and 21 other tissues See more
Orthologs

Genomic context

See ZNF280C in Genome Data Viewer
Location:
Xq26.1
Exon count:
19
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (130202707..130268899, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (129336673..129402922, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene E74 like ETS transcription factor 4 Neighboring gene RAB33A, member RAS oncogene family Neighboring gene apoptosis inducing factor mitochondria associated 1 Neighboring gene RNA, U6 small nuclear 1130, pseudogene Neighboring gene SNRPN upstream reading frame protein pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20095

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 280C
Names
suppressor of hairy wing homolog 3
zinc finger protein 633
zinc finger protein proximal to RAD eighteen

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_021388.2 RefSeqGene

    Range
    5050..71242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_017666.5NP_060136.1  zinc finger protein 280C

    See identical proteins and their annotated locations for NP_060136.1

    Status: VALIDATED

    Source sequence(s)
    AL139234, BC051728, DA441065
    Consensus CDS
    CCDS14622.1
    UniProtKB/Swiss-Prot
    Q8ND82
    Related
    ENSP00000360017.4, ENST00000370978.9
    Conserved Domains (2) summary
    sd00017
    Location:355376
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:46227
    DUF4195; Domain of unknown function (DUF4195)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    130202707..130268899 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006724765.3XP_006724828.1  zinc finger protein 280C isoform X1

    See identical proteins and their annotated locations for XP_006724828.1

    Related
    ENSP00000408521.1, ENST00000447817.1
    Conserved Domains (2) summary
    sd00017
    Location:355376
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:46227
    DUF4195; Domain of unknown function (DUF4195)
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