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PPARD peroxisome proliferator activated receptor delta [ Homo sapiens (human) ]

Gene ID: 5467, updated on 17-Jun-2024

Summary

Official Symbol
PPARDprovided by HGNC
Official Full Name
peroxisome proliferator activated receptor deltaprovided by HGNC
Primary source
HGNC:HGNC:9235
See related
Ensembl:ENSG00000112033 MIM:600409; AllianceGenome:HGNC:9235
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB
Summary
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]
Expression
Ubiquitous expression in placenta (RPKM 13.1), thyroid (RPKM 10.8) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See PPARD in Genome Data Viewer
Location:
6p21.31
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (35342558..35428178)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (35165619..35251256)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (35310335..35395955)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17086 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17087 Neighboring gene zinc finger protein 76 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr6:35253595-35254794 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:35263932-35264096 Neighboring gene Sharpr-MPRA regulatory region 9100 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24398 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:35280323-35280822 Neighboring gene DEF6 guanine nucleotide exchange factor Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17088 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17089 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17090 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17091 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24399 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:35328305-35329201 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24400 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24401 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24402 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:35351066-35351668 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:35359676-35360244 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24403 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24404 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:35378432-35378965 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:35378966-35379498 Neighboring gene Sharpr-MPRA regulatory region 9405 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17092 Neighboring gene makorin ring finger protein 6, pseudogene Neighboring gene FA complementation group E

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
EBI GWAS Catalog
Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.
EBI GWAS Catalog
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
EBI GWAS Catalog
Novel susceptibility genes associated with diabetic cataract in a Taiwanese population.
EBI GWAS Catalog

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr regulates mitochondrial respiration and enhances the activity of hydroxyacyl-CoA dehydrogenase (HADH) through PPARbeta/delta PubMed
vpr HIV-1 Vpr enhances PPARbeta/delta-induced PDK4, carnitine palmitoyltransferase I (CPT1), and acetyl-coenzyme A acyltransferase 2 (ACAA2) mRNA expression in cells PubMed
vpr HIV-1 Vpr enhances PPARbeta/delta agonist GW501516-induced pyruvate dehydrogenase kinase 4 (PDK4) protein expression and phosphorylation of pyruvate dehydrogenase alpha 1 (PDHE1alpha) at serine 293 in cells PubMed
vpr HIV-1 Vpr physically interacts with the LXXLL motif (residues 64-68) of PPARbeta/delta in vivo and in vitro and enhances PPARbeta/delta-induced transcription activity PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC3931

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables linoleic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lipid binding IDA
Inferred from Direct Assay
more info
PubMed 
enables nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nuclear receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nuclear steroid receptor activity TAS
Traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription coactivator binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in adipose tissue development IEA
Inferred from Electronic Annotation
more info
 
involved_in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in axon ensheathment ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell population proliferation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell-substrate adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to nutrient levels IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cholesterol metabolic process TAS
Traceable Author Statement
more info
PubMed 
involved_in decidualization TAS
Traceable Author Statement
more info
PubMed 
involved_in embryo implantation TAS
Traceable Author Statement
more info
PubMed 
involved_in energy homeostasis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in energy homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in fat cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid beta-oxidation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in fatty acid beta-oxidation TAS
Traceable Author Statement
more info
PubMed 
involved_in fatty acid catabolic process TAS
Traceable Author Statement
more info
PubMed 
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fatty acid transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in generation of precursor metabolites and energy TAS
Traceable Author Statement
more info
PubMed 
involved_in glucose metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
involved_in glucose transmembrane transport NAS
Non-traceable Author Statement
more info
PubMed 
involved_in hormone-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in keratinocyte migration IEA
Inferred from Electronic Annotation
more info
 
involved_in keratinocyte proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in lipid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of cholesterol storage IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of miRNA transcription ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of myoblast differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of fat cell differentiation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in positive regulation of fat cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of myoblast proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of skeletal muscle tissue regeneration IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of skeletal muscle satellite cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in steroid hormone mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in wound healing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of chromatin ISA
Inferred from Sequence Alignment
more info
 
part_of chromatin ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
peroxisome proliferator-activated receptor delta
Names
PPAR-beta
PPAR-delta
PPARD/MYO1D fusion
nuclear hormone receptor 1
nuclear receptor subfamily 1 group C member 2
peroxisome proliferator-activated receptor beta

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012345.2 RefSeqGene

    Range
    5001..90621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001171818.2NP_001165289.1  peroxisome proliferator-activated receptor delta isoform 1

    See identical proteins and their annotated locations for NP_001165289.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants 1 and 3 encode the same isoform (1).
    Source sequence(s)
    AB099507, AK122614, AL022721, BE503383, DA192442
    Consensus CDS
    CCDS4803.1
    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Related
    ENSP00000310928.4, ENST00000311565.4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  2. NM_001171819.2NP_001165290.1  peroxisome proliferator-activated receptor delta isoform 3

    See identical proteins and their annotated locations for NP_001165290.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AK122614, AK296425, AL022721, BE503383, DA192442
    Consensus CDS
    CCDS54994.1
    UniProtKB/TrEMBL
    B4E2Y1
    Related
    ENSP00000414372.2, ENST00000448077.6
    Conserved Domains (2) summary
    cd06932
    Location:134401
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:34117
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  3. NM_001171820.2NP_001165291.1  peroxisome proliferator-activated receptor delta isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks two in-frame exons in the coding region, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
    Source sequence(s)
    AK122614, AK304878, AL022721, BE503383, DA192442
    Consensus CDS
    CCDS54995.1
    UniProtKB/TrEMBL
    B4E2Y1
    Related
    ENSP00000413314.2, ENST00000418635.6
    Conserved Domains (2) summary
    cd06932
    Location:75342
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cl02596
    Location:4158
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
  4. NM_006238.5NP_006229.1  peroxisome proliferator-activated receptor delta isoform 1

    See identical proteins and their annotated locations for NP_006229.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). Both variants 1 and 3 encode the same isoform (1).
    Source sequence(s)
    AK122614, BE503383, DA192442
    Consensus CDS
    CCDS4803.1
    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Related
    ENSP00000353916.3, ENST00000360694.8
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  5. NM_177435.3NP_803184.1  peroxisome proliferator-activated receptor delta isoform 2

    See identical proteins and their annotated locations for NP_803184.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate exon in the 3' coding region and 3'UTR. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AL022721, BC002715, CN332566, DA192442, DA476590
    Consensus CDS
    CCDS4804.1
    UniProtKB/TrEMBL
    F1D8S7
    Related
    ENSP00000337063.2, ENST00000337400.6
    Conserved Domains (2) summary
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    cl11397
    Location:173359
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    35342558..35428178
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047418925.1XP_047274881.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  2. XM_017010974.2XP_016866463.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  3. XM_005249193.2XP_005249250.1  peroxisome proliferator-activated receptor delta isoform X1

    See identical proteins and their annotated locations for XP_005249250.1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  4. XM_047418919.1XP_047274875.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  5. XM_047418922.1XP_047274878.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  6. XM_047418929.1XP_047274885.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  7. XM_011514707.2XP_011513009.1  peroxisome proliferator-activated receptor delta isoform X1

    See identical proteins and their annotated locations for XP_011513009.1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  8. XM_047418935.1XP_047274891.1  peroxisome proliferator-activated receptor delta isoform X2

  9. XM_047418923.1XP_047274879.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  10. XM_047418920.1XP_047274876.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  11. XM_047418921.1XP_047274877.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  12. XM_047418930.1XP_047274886.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  13. XM_047418934.1XP_047274890.1  peroxisome proliferator-activated receptor delta isoform X2

  14. XM_047418924.1XP_047274880.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  15. XM_047418915.1XP_047274871.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  16. XM_011514710.2XP_011513012.1  peroxisome proliferator-activated receptor delta isoform X1

    See identical proteins and their annotated locations for XP_011513012.1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  17. XM_047418917.1XP_047274873.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  18. XM_047418928.1XP_047274884.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  19. XM_047418918.1XP_047274874.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  20. XM_047418916.1XP_047274872.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  21. XM_017010973.2XP_016866462.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  22. XM_047418933.1XP_047274889.1  peroxisome proliferator-activated receptor delta isoform X2

  23. XM_047418932.1XP_047274888.1  peroxisome proliferator-activated receptor delta isoform X2

  24. XM_006715123.2XP_006715186.1  peroxisome proliferator-activated receptor delta isoform X1

    See identical proteins and their annotated locations for XP_006715186.1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
    Conserved Domains (2) summary
    cd06932
    Location:173440
    NR_LBD_PPAR; The ligand binding domain of peroxisome proliferator-activated receptors
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
  25. XM_047418936.1XP_047274892.1  peroxisome proliferator-activated receptor delta isoform X2

  26. XM_047418927.1XP_047274883.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  27. XM_047418937.1XP_047274893.1  peroxisome proliferator-activated receptor delta isoform X2

  28. XM_047418931.1XP_047274887.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  29. XM_047418926.1XP_047274882.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  30. XM_024446474.2XP_024302242.1  peroxisome proliferator-activated receptor delta isoform X2

    Conserved Domains (2) summary
    cd06965
    Location:73156
    NR_DBD_Ppar; DNA-binding domain of peroxisome proliferator-activated receptors (PPAR) is composed of two C4-type zinc fingers
    cl11397
    Location:173359
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    35165619..35251256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054355721.1XP_054211696.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  2. XM_054355712.1XP_054211687.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  3. XM_054355713.1XP_054211688.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  4. XM_054355707.1XP_054211682.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  5. XM_054355719.1XP_054211694.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  6. XM_054355706.1XP_054211681.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  7. XM_054355725.1XP_054211700.1  peroxisome proliferator-activated receptor delta isoform X2

  8. XM_054355710.1XP_054211685.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  9. XM_054355708.1XP_054211683.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  10. XM_054355709.1XP_054211684.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  11. XM_054355720.1XP_054211695.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  12. XM_054355724.1XP_054211699.1  peroxisome proliferator-activated receptor delta isoform X2

  13. XM_054355711.1XP_054211686.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  14. XM_054355701.1XP_054211676.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  15. XM_054355703.1XP_054211678.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  16. XM_054355704.1XP_054211679.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  17. XM_054355717.1XP_054211692.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  18. XM_054355705.1XP_054211680.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  19. XM_054355702.1XP_054211677.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  20. XM_054355718.1XP_054211693.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  21. XM_054355723.1XP_054211698.1  peroxisome proliferator-activated receptor delta isoform X2

  22. XM_054355722.1XP_054211697.1  peroxisome proliferator-activated receptor delta isoform X2

  23. XM_054355715.1XP_054211690.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  24. XM_054355727.1XP_054211702.1  peroxisome proliferator-activated receptor delta isoform X2

  25. XM_054355728.1XP_054211703.1  peroxisome proliferator-activated receptor delta isoform X2

  26. XM_054355716.1XP_054211691.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4
  27. XM_054355726.1XP_054211701.1  peroxisome proliferator-activated receptor delta isoform X2

  28. XM_054355714.1XP_054211689.1  peroxisome proliferator-activated receptor delta isoform X1

    UniProtKB/Swiss-Prot
    A8K6J6, B4E3V3, B6ZGS1, B7Z3W1, E9PE18, Q03181, Q5D1P0, Q7Z5K0, Q9BUD4