PLK5 polo like kinase 5 (inactive) [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PLK5provided by VGNC
Official Full Name: polo like kinase 5 (inactive)provided by VGNC
Primary source: VGNC:VGNC:111637
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	20	NC_051824.1 (58069085..58075340, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	20	NC_006602.4 (57129851..57136106, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	20	NC_049241.1 (57806577..57812829, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	20	NC_049280.1 (57125378..57131609, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	20	NC_049761.1 (57604652..57610898, complement)

Chromosome 20 - NC_051824.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cytokinesis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in spindle pole	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5; inactive serine/threonine-protein kinase PLK5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051824.1 Reference ROS_Cfam_1.0

Range

58069085..58075340 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038429292.1 → XP_038285220.1 LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5 isoform X1

UniProtKB/TrEMBL

A0A8C0N8H4, A0A8P0SST1

Conserved Domains (2) summary

cd13118
Location:426 → 501

POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5

cd14099
Location:26 → 282

STKc_PLK; Catalytic domain of the Serine/Threonine Kinases, Polo-like kinases

Alternate UMICH_Zoey_3.1

Genomic

NC_049280.1 Alternate UMICH_Zoey_3.1

Range

57125378..57131609 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038504824.1 → XP_038360752.1 inactive serine/threonine-protein kinase PLK5 isoform X1
XM_038504825.1 → XP_038360753.1 inactive serine/threonine-protein kinase PLK5 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049761.1 Alternate UNSW_CanFamBas_1.0

Range

57604652..57610898 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038632087.1 → XP_038488015.1 LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5 isoform X3

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049241.1 Alternate UU_Cfam_GSD_1.0

Range

57806577..57812829 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038567971.1 → XP_038423899.1 LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5 isoform X4

UniProtKB/TrEMBL

A0A8C0N8H4, A0A8P0SST1

Conserved Domains (2) summary

cd13118
Location:425 → 452

POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5

cd14099
Location:26 → 282

STKc_PLK; Catalytic domain of the Serine/Threonine Kinases, Polo-like kinases

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

57129851..57136106 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_014122403.3 → XP_013977878.1 LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5 isoform X5

UniProtKB/TrEMBL

A0A8C0N8H4, A0A8P0SST1

Conserved Domains (2) summary

cd13118
Location:425 → 452

POLO_box_1; First polo-box domain (PBD) of polo-like kinases Plk1, Plk2, Plk3, and Plk5

cd14099
Location:26 → 282

STKc_PLK; Catalytic domain of the Serine/Threonine Kinases, Polo-like kinases