ZIC4 Zic family member 4 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ZIC4provided by VGNC
Official Full Name: Zic family member 4provided by VGNC
Primary source: VGNC:VGNC:7140
Locus tag: CK820_G0006418
See related: Ensembl:ENSPTRG00000015500
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	2	NC_086015.1 (150576791..150597460, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	3	NC_072401.1 (150486162..150506831, complement)

Chromosome 2 - NC_086015.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH91704 (e-PCR)
- UniSTS:83715

D3S3991 (e-PCR)
- UniSTS:1296

G33011 (e-PCR)
- UniSTS:117588

D3S2841E (e-PCR)
- UniSTS:150869

SHGC-31137 (e-PCR)
- UniSTS:64627

A009Z14 (e-PCR)
- UniSTS:51329

SGC30596 (e-PCR)
- UniSTS:46763

SHGC-77439 (e-PCR)
- UniSTS:57849

ZIC4_2201 (e-PCR)
- UniSTS:281086

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: zinc finger protein ZIC 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

150576791..150597460 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009446648.4 → XP_009444923.1 zinc finger protein ZIC 4 isoform X2

See identical proteins and their annotated locations for XP_009444923.1

UniProtKB/TrEMBL

A0A2I3RKS0, A0A2J8P2W6, A0A6D2WBS1

Related

ENSPTRP00000065258.1

Conserved Domains (2) summary

COG5048
Location:142 → 288

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:178 → 198

ZF_C2H2; C2H2 Zn finger [structural motif]
XM_063807266.1 → XP_063663336.1 zinc finger protein ZIC 4 isoform X4

UniProtKB/TrEMBL

A0A2J8P2X9
XM_009446646.5 → XP_009444921.1 zinc finger protein ZIC 4 isoform X5

UniProtKB/TrEMBL

A0A2J8P2X3

Conserved Domains (2) summary

COG5048
Location:180 → 326

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:216 → 236

ZF_C2H2; C2H2 Zn finger [structural motif]
XM_009446653.5 → XP_009444928.1 zinc finger protein ZIC 4 isoform X3

See identical proteins and their annotated locations for XP_009444928.1

Conserved Domains (2) summary

sd00017
Location:80 → 102

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:108 → 132

zf-C2H2; Zinc finger, C2H2 type
XM_526339.9 → XP_526339.3 zinc finger protein ZIC 4 isoform X1

See identical proteins and their annotated locations for XP_526339.3

UniProtKB/TrEMBL

A0A2J8P2Z5, A0A6D2W6U6, H2R7Z8

Related

ENSPTRP00000051009.4

Conserved Domains (2) summary

COG5048
Location:192 → 338

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:228 → 248

ZF_C2H2; C2H2 Zn finger [structural motif]