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DDX21 DExD-box helicase 21 [ Pan troglodytes (chimpanzee) ]

Gene ID: 450500, updated on 17-Aug-2024

Summary

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Official Symbol
DDX21provided by VGNC
Official Full Name
DExD-box helicase 21provided by VGNC
Primary source
VGNC:VGNC:12293
Locus tag
CK820_G0007983
See related
Ensembl:ENSPTRG00000002563
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (81157820..81195806)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (71772857..71810832)

Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene storkhead box 1 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene DExD-box helicase 50 Neighboring gene mediator of RNA polymerase II transcription subunit 28-like Neighboring gene kinesin family binding protein Neighboring gene actin, cytoplasmic 2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in central nervous system projection neuron axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron projection maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nucleolar RNA helicase 2
Names
DEAD (Asp-Glu-Ala-Asp) box helicase 21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
DEAD-box helicase 21
XP_009456870.1
XP_054515637.1
XP_507825.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    81157820..81195806
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_507825.9 → XP_507825.2  nucleolar RNA helicase 2 isoform X1

    See identical proteins and their annotated locations for XP_507825.2

    UniProtKB/TrEMBL
    A0A2I3SHS3, A0A2J8NV11, A0A6D2WAH5, H2Q201
    Related
    ENSPTRP00000004431.4
    Conserved Domains (4) summary
    COG0513
    Location:178 → 587
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd12936
    Location:617 → 709
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins
    cd17944
    Location:197 → 398
    DEADc_DDX21_DDX50; DEAD-box helicase domain of DEAD box proteins 21 and 50
    cl17173
    Location:718 → 771
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  2. XM_009458595.5 → XP_009456870.1  nucleolar RNA helicase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SHS3
    Conserved Domains (5) summary
    PTZ00424
    Location:168 → 554
    PTZ00424; helicase 45; Provisional
    cd00079
    Location:411 → 538
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:188 → 395
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    cd12936
    Location:617 → 694
    GUCT_RHII_Gualpha_beta; RNA-binding GUCT domain found in vertebrate RNA helicase II/Gualpha (RH-II/Gualpha), RNA helicase II/Gubeta (RH-II/Gubeta) and similar proteins
    cl17173
    Location:703 → 756
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

  3. XM_054659662.2 → XP_054515637.1  nucleolar RNA helicase 2 isoform X3

    UniProtKB/TrEMBL
    A0A2I3SHS3, A0A2J8NV13
Nucleotide Protein
Heading Accession and Version

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