Conserved Protein Domain Family
SrmB

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COG0513: SrmB 
Superfamily II DNA and RNA helicase [Replication, recombination and repair]
Statistics
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PSSM-Id: 223587
View PSSM: COG0513
Aligned: 218 rows
Threshold Bit Score: 49.4034
Threshold Setting Gi: 6319356
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792  800 RNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMAdtPSVAVQAPPGYG 879
gi 6319357  314 RNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMAdtPSVAVQAPPGYG 393
gi 6320756  161 RNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMAdtPSVAVQAPPGYG 240
gi 1175970    1 ----------------------------------------------------------------MAdtPSVAVQAPPGYG 16
gi 731626     1 ----------------------------------------------------------------MAdtPSVAVQAPPGYG 16
gi 731585   250 RNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMAdtPSVAVQAPPGYG 329
gi 731903   607 RNAEDVVAGEAASSNHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMAdtPSVAVQAPPGYG 686
gi 1176490  607 RNAEDVVAGEAASSNHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMAdtPSVAVQAPPGYG 686
gi 6322961  145 RNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMAdtPSVAVQAPPGYG 224
gi 6325462    1 ----------------------------------------------------------------MAdtPSVAVQAPPGYG 16
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792  880 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 959
gi 6319357  394 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 473
gi 6320756  241 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVApvrNFIeegydgVTDLYVGIYDDLASTNFTDr 320
gi 1175970   17 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVApvrNFIeegydgVTDLYVGIYDDLASTNFTDr 96
gi 731626    17 KTELFHLPLIALASKGDVEYVSFLFVPYTVLLANCMIRLGRCGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 96
gi 731585   330 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 409
gi 731903   687 KTELFHLPLIALASKGDVEYVSFLFVPYTVLLANCMIRLGRCGCLNVApvrNFIeegydgVTDLYVGIYDDLASTNFTDr 766
gi 1176490  687 KTELFHLPLIALASKGDVEYVSFLFVPYTVLLANCMIRLGRRGCLNVApvrNFIeegydgVTDLYVGIYDDLASTNFTDr 766
gi 6322961  225 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 304
gi 6325462   17 KTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRCGCLNVApvrNFIeegcdgVTDLYVGIYDDLASTNFTDr 96
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792  960 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 1039
gi 6319357  474 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 553
gi 6320756  321 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 400
gi 1175970   97 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 176
gi 731626    97 iAaWENIVECTFRTNNVKLGYlivdELHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 176
gi 731585   410 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 489
gi 731903   767 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 846
gi 1176490  767 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 846
gi 6322961  305 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 384
gi 6325462   97 iAaWENIVECTFRTNNVKLGYlivdEFHNFETEVYRQSQFGGITNLdfdAFEKAIFLSGTAPEAvadaaLQRIGLTGLAK 176
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792 1040 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 1119
gi 6319357  554 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 633
gi 6320756  401 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIRKKVESQPeEALKLLLALFESEPESKAIVVASTTNEV 480
gi 1175970  177 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 256
gi 731626   177 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSKVPLG------------------------------------------ 214
gi 731585   490 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 569
gi 731903   847 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIRKKVESQPeEALKLLLALFESEPESKAIVVASTTNEV 926
gi 1176490  847 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIRKKVESQPeEALKLLLALFESEPESKAIVVASTTNEV 926
gi 6322961  385 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 464
gi 6325462  177 KSmDINELKRSEDLsRGLssyPTRMFnliKEKSEVPLGHVHKIWKKVESQPeEALKLLLALFEIEPESKAIVVASTTNEV 256
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792 1120 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 1199
gi 6319357  634 EELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCh---------------------------------------------- 667
gi 6320756  481 EELACSWRKYFRVVWIHGKLDAAEKVSRTKEFVtDGNMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 560
gi 1175970  257 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 336
gi 731626       --------------------------------------------------------------------------------
gi 731585   570 EELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCh---------------------------------------------- 603
gi 731903   927 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 1006
gi 1176490  927 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 1006
gi 6322961  465 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 544
gi 6325462  257 EELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVtDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRD 336
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792 1200 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 1279
gi 6319357      --------------------------------------------------------------------------------
gi 6320756  561 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 640
gi 1175970  337 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccvC------------------------ 392
gi 731626       --------------------------------------------------------------------------------
gi 731585       --------------------------------------------------------------------------------
gi 731903  1007 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 1086
gi 1176490 1007 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 1086
gi 6322961  545 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 624
gi 6325462  337 GGlcyllsrknswaarnRKGELPPIKEGciTEQVREFYGLESKKGKKGQhvgccgSRTDLSADTVELIermdrlaekqat 416
                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792 1280 aSMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSAnast------------------------------------- 1322
gi 6319357      --------------------------------------------------------------------------------
gi 6320756  641 aSMSIVALPSNFQESNSSDRYRKYCSSDEDSNTCIHGSAnastnastnaittastnvrt------------nattnastn 708
gi 1175970      --------------------------------------------------------------------------------
gi 731626       --------------------------------------------------------------------------------
gi 731585       --------------------------------------------------------------------------------
gi 731903  1087 aSMSIVALPSSFQESNSSDRYRKYCSSDEDSNTCIHGSAnastnastnaittastnvrtnattnastnattnastnastn 1166
gi 1176490 1087 aSMSIVALPSSFQESNSSDRYRKYCSSDEDSNTCIHGSAnastnastnaittastnvrtnattnastnattnastnastn 1166
gi 6322961  625 aSMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSAnast------------------------------------- 667
gi 6325462  417 aSMSIVALPSSFQESNSSDRCRKYCSSDEDSNTCIHGSAnast------------------------------------- 459
                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1723792 1323 -------natTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNSSTNatttastnvrtsatttas---------- 1385
gi 6319357      --------------------------------------------------------------------------------
gi 6320756  709 attnastnatTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNsstnatttasinvrtsatttksinss------ 782
gi 1175970      --------------------------------------------------------------------------------
gi 731626   215 --------------TNATTTASTNVRTSATTtasInvrtsatT------------------------------------- 243
gi 731585       --------------------------------------------------------------------------------
gi 731903  1167 attnastnatTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNSSTNatttestnsstnatttestnsntsattt 1246
gi 1176490 1167 attnastnatTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNSSTNatttestnsstnatttestnsntsattt 1246
gi 6322961  668 -------natTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNSSTNatttastnvrtsatttasinvrtsattt 740
gi 6325462  460 -------natTNSSTNATTTASTNVRTSATTtasInvrtsatTTESTNSSTNatttastnvrtsatttasinvrtsattt 532
                       650       660       670       680       690       700       710
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1723792 1386 --------------------------invrtsatttestnsntSATTTESTDSNTSATTTESTDSNTSATTTAST 1434
gi 6319357      ---------------------------------------------------------------------------
gi 6320756  783 ------------------tnatitestnsntnatttestnsktSATTTASTNSNTSATTTESTNSKTSATTTAST 839
gi 1175970      ---------------------------------------------------------------------------
gi 731626   244 -----------------------------------------------TASINVRTSATTTESTNSNTNATTTEST 271
gi 731585       ---------------------------------------------------------------------------
gi 731903  1247 asinvrtsatttestnsstsatttasinvrtsatttksinsstNATTTESTNSNTNATTTESTNSSTNATTTEST 1321
gi 1176490 1247 asinvrtsatttestnsstsatttasinvrtsatttksinsstNATTTESTNSNTNATTTESTNSSTNATTTEST 1321
gi 6322961  741 es------------tnsntsatttestdsntsatttestdsstNATTTASINVRTSATTTESTNSNTNATTTEST 803
gi 6325462  533 es------------tnsntsatttestdsntsatttestnsstNATTTASINVRTSATTTESTNSNTNATTTEST 595
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