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DECR2 2,4-dienoyl-CoA reductase 2 [ Homo sapiens (human) ]

Gene ID: 26063, updated on 23-Nov-2021

Summary

Official Symbol
DECR2provided by HGNC
Official Full Name
2,4-dienoyl-CoA reductase 2provided by HGNC
Primary source
HGNC:HGNC:2754
See related
Ensembl:ENSG00000242612 MIM:615839
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PDCR; SDR17C1
Expression
Broad expression in kidney (RPKM 18.7), liver (RPKM 15.2) and 25 other tissues See more
Orthologs
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Genomic context

See DECR2 in Genome Data Viewer
Location:
16p13.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (401885..412482)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (451885..462482)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100134368 Neighboring gene uncharacterized LOC105371036 Neighboring gene ribosomal protein L23a pseudogene 5 Neighboring gene NME/NM23 nucleoside diphosphate kinase 4 Neighboring gene RAB11 family interacting protein 3 Neighboring gene long intergenic non-protein coding RNA 235

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: NME4

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytosol TAS
Traceable Author Statement
more info
 
located_in peroxisomal membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Names
2,4-dienoyl-CoA reductase 2, peroxisomal
peroxisomal 2,4-dienoyl-CoA reductase
short chain dehydrogenase/reductase family 17C member 1
NP_065715.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020664.4NP_065715.1  peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

    See identical proteins and their annotated locations for NP_065715.1

    Status: VALIDATED

    Source sequence(s)
    BC010740, BC030226
    Consensus CDS
    CCDS10409.1
    UniProtKB/Swiss-Prot
    Q9NUI1
    Related
    ENSP00000219481.5, ENST00000219481.10
    Conserved Domains (1) summary
    cd05369
    Location:26273
    TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    401885..412482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187610.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    1031..11628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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