ABI3BP ABI family member 3 binding protein [ Homo sapiens (human) ]

Gene ID: 25890, updated on 16-Oct-2021

Summary

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Official Symbol: ABI3BPprovided by HGNC
Official Full Name: ABI family member 3 binding proteinprovided by HGNC
Primary source: HGNC:HGNC:17265
See related: Ensembl:ENSG00000154175 MIM:606279
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: TARSH; NESHBP
Expression: Broad expression in gall bladder (RPKM 33.8), lung (RPKM 26.2) and 21 other tissues See more
Orthologs: mouse all
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Genomic context

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See ABI3BP in Genome Data Viewer

Location:: 3q12.2

Exon count:: 68

Annotation release	Status	Assembly	Chr	Location
109.20210514	current	GRCh38.p13 (GCF_000001405.39)	3	NC_000003.12 (100749156..100993508, complement)
105.20201022	previous assembly	GRCh37.p13 (GCF_000001405.25)	3	NC_000003.11 (100468000..100712265, complement)

Chromosome 3 - NC_000003.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Depletion of ABI3BP by MicroRNA-183 Promotes the Development of Esophageal Carcinoma.
Title: The Depletion of ABI3BP by MicroRNA-183 Promotes the Development of Esophageal Carcinoma.
The current study clarifies that MALAT1 silencing and ABI3BP elevation impede the GBC development through the H3K27 methylation suppression induced by EZH2, highlighting a promising competitive paradigm for therapeutic approaches of GBC.
Title: Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells.
ABI3BP is a susceptibility gene for Kashin-Beck disease in the Chinese Han population.
Title: Genome-wide copy number variation study and gene expression analysis identify ABI3BP as a susceptibility gene for Kashin-Beck disease.
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Genome-wide association study of suicide attempts in mood disorder patients.
These results suggest that TARSH plays an important role in proliferation of replicative senescence and may serve as a trigger of tumor development.
Title: Implication of p53-dependent cellular senescence related gene, TARSH in tumor suppression.
Observational study of gene-disease association. (HuGE Navigator)
Title: Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
The loss of ABI3BP expression could play a functional role in thyroid tumorigenesis.
Title: Re-expression of ABI3-binding protein suppresses thyroid tumor growth by promoting senescence and inhibiting invasion.
Thus, TARSH presumably represents a trigger gene for evoking cellular senescence, which has also been suggested to be involved in the prevention of tumorigenesis.
Title: Expression of TARSH gene in MEFs senescence and its potential implication in human lung cancer.
expression of TARSH mRNA is remarkably downregulated in all lung cancer cell lines examined; also TARSH expression was significantly low in all of the tumor specimens when compared to the expression in corresponding non-neoplastic lung tissue specimens
Title: Cancer-associated loss of TARSH gene expression in human primary lung cancer.

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Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations. GeneReviews: Not available
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. GeneReviews: Not available

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH119344 (e-PCR)
- UniSTS:133906

D3S3966 (e-PCR)
- UniSTS:25876

D8S2279 (e-PCR)
- UniSTS:473907

D3S4006 (e-PCR)
- UniSTS:44087

L18426 (e-PCR)
- UniSTS:34648

G54792 (e-PCR)
- UniSTS:117875

SHGC-112259 (e-PCR)
- UniSTS:168578

SHGC-57683 (e-PCR)
- UniSTS:57992

SHGC-36323 (e-PCR)
- UniSTS:73388

SHGC-83101 (e-PCR)
- UniSTS:101327

SHGC-77161 (e-PCR)
- UniSTS:63187

SHGC-77160 (e-PCR)
- UniSTS:6896

Homology

Orthologs from Annotation Pipeline: 377 organisms have orthologs with human gene ABI3BP
Orthologs

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables extracellular matrix structural constituent	RCA inferred from Reviewed Computational Analysis more info	PubMed

Component	Evidence Code	Pubs
colocalizes_with collagen-containing extracellular matrix	HDA more info	PubMed
located_in collagen-containing extracellular matrix	HDA more info	PubMed
located_in extracellular region	HDA more info	PubMed
located_in extracellular space	HDA more info	PubMed

General protein information

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Preferred Names: target of Nesh-SH3

Names: ABI family, member 3 (NESH) binding protein; ABI gene family member 3-binding protein; ABI gene family, member 3 (NESH) binding protein; nesh-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001349329.2 → NP_001336258.2 target of Nesh-SH3 isoform 1 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:700 → 1197

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1080 → 1332

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1479 → 1570

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001349330.2 → NP_001336259.2 target of Nesh-SH3 isoform 2 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:670 → 1127

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1010 → 1262

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1409 → 1500

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001349331.2 → NP_001336260.2 target of Nesh-SH3 isoform 3 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Related

ENSP00000419029.3, ENST00000486770.7

Conserved Domains (3) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:422 → 845

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:986 → 1077

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001349332.2 → NP_001336261.2 target of Nesh-SH3 isoform 4 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:257 → 591

PHA03247; large tegument protein UL36; Provisional

PHA03307
Location:422 → 832

PHA03307; transcriptional regulator ICP4; Provisional

cd00063
Location:857 → 948

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001365642.2 → NP_001352571.2 target of Nesh-SH3 isoform 6 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (3) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:447 → 867

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1108 → 1199

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001365643.2 → NP_001352572.2 target of Nesh-SH3 isoform 7 precursor

Status: VALIDATED

Source sequence(s)

AC080014, AC093009, AC106721

Related

ENSP00000433993.2, ENST00000495063.6

Conserved Domains (2) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:471 → 926

PHA03247; large tegument protein UL36; Provisional
NM_001375547.2 → NP_001362476.1 target of Nesh-SH3 isoform 8 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Related

ENSP00000420524.2, ENST00000471714.6

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:771 → 1268

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1151 → 1403

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1550 → 1641

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001375549.2 → NP_001362478.1 target of Nesh-SH3 isoform 9 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:771 → 1268

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1151 → 1387

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1534 → 1625

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001375550.1 → NP_001362479.1 target of Nesh-SH3 isoform 10 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:757 → 1254

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1137 → 1389

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1536 → 1627

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_001377332.1 → NP_001364261.1 target of Nesh-SH3 isoform 11 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Conserved Domains (4) summary

PTZ00449
Location:900 → 1258

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

PHA03247
Location:533 → 1073

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:1301 → 1392

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl21522
Location:116 → 195

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
NM_015429.4 → NP_056244.3 target of Nesh-SH3 isoform 5 precursor

Status: VALIDATED

Source sequence(s)

AC068763, AC069223, AC080014, AC093009, AC106721

Consensus CDS

CCDS46880.1

Related

ENSP00000284322.6, ENST00000284322.10

Conserved Domains (4) summary

PTZ00449
Location:477 → 789

PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional

smart00060
Location:117 → 195

FN3; Fibronectin type 3 domain

PHA03247
Location:257 → 591

PHA03247; large tegument protein UL36; Provisional

cd00063
Location:832 → 923

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

NC_000003.12 Reference GRCh38.p13 Primary Assembly

Range

100749156..100993508 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024453445.1 → XP_024309213.1 target of Nesh-SH3 isoform X48

Conserved Domains (4) summary

cd00063
Location:1463 → 1554

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl21522
Location:123 → 202

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl26464
Location:724 → 1181

Atrophin-1; Atrophin-1 family

cl28087
Location:1064 → 1316

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
XM_005247299.4 → XP_005247356.1 target of Nesh-SH3 isoform X29

Conserved Domains (2) summary

cd00063
Location:1508 → 1599

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512656.2 → XP_011510958.1 target of Nesh-SH3 isoform X42

Conserved Domains (2) summary

cd00063
Location:1458 → 1549

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_006713572.3 → XP_006713635.1 target of Nesh-SH3 isoform X39

Conserved Domains (2) summary

cd00063
Location:1483 → 1574

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512660.2 → XP_011510962.1 target of Nesh-SH3 isoform X45

Conserved Domains (2) summary

cd00063
Location:1436 → 1527

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512641.2 → XP_011510943.1 target of Nesh-SH3 isoform X12

Conserved Domains (4) summary

smart00060
Location:124 → 202

FN3; Fibronectin type 3 domain

PHA03247
Location:753 → 1250

PHA03247; large tegument protein UL36; Provisional

PRK10263
Location:1133 → 1385

PRK10263; DNA translocase FtsK; Provisional

cd00063
Location:1532 → 1623

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_011512648.2 → XP_011510950.1 target of Nesh-SH3 isoform X25

Conserved Domains (2) summary

cd00063
Location:1511 → 1602

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247288.3 → XP_005247345.1 target of Nesh-SH3 isoform X10

Conserved Domains (2) summary

cd00063
Location:1533 → 1624

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_006713571.3 → XP_006713634.1 target of Nesh-SH3 isoform X37

Conserved Domains (2) summary

cd00063
Location:1485 → 1576

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512640.2 → XP_011510942.1 target of Nesh-SH3 isoform X9

Conserved Domains (2) summary

cd00063
Location:1535 → 1626

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247306.3 → XP_005247363.1 target of Nesh-SH3 isoform X46

Conserved Domains (2) summary

cd00063
Location:1421 → 1512

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512653.2 → XP_011510955.1 target of Nesh-SH3 isoform X38

Conserved Domains (2) summary

cd00063
Location:1483 → 1574

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247300.3 → XP_005247357.1 target of Nesh-SH3 isoform X31

Conserved Domains (2) summary

cd00063
Location:1499 → 1590

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512643.2 → XP_011510945.1 target of Nesh-SH3 isoform X16

Conserved Domains (2) summary

cd00063
Location:1530 → 1621

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512647.2 → XP_011510949.1 target of Nesh-SH3 isoform X23

Conserved Domains (2) summary

cd00063
Location:1512 → 1603

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512654.2 → XP_011510956.1 target of Nesh-SH3 isoform X40

Conserved Domains (2) summary

cd00063
Location:1480 → 1571

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512657.2 → XP_011510959.1 target of Nesh-SH3 isoform X43

Conserved Domains (2) summary

cd00063
Location:1457 → 1548

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512646.2 → XP_011510948.1 target of Nesh-SH3 isoform X19

Conserved Domains (2) summary

cd00063
Location:1526 → 1617

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_006713570.3 → XP_006713633.1 target of Nesh-SH3 isoform X32

Conserved Domains (2) summary

cd00063
Location:1495 → 1586

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247295.3 → XP_005247352.1 target of Nesh-SH3 isoform X24

Conserved Domains (2) summary

cd00063
Location:1511 → 1602

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_024453444.1 → XP_024309212.1 target of Nesh-SH3 isoform X22

Conserved Domains (4) summary

smart00060
Location:124 → 202

FN3; Fibronectin type 3 domain

cd00063
Location:1512 → 1603

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

cl26464
Location:803 → 1230

Atrophin-1; Atrophin-1 family

cl28087
Location:1113 → 1365

FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
XM_005247289.3 → XP_005247346.1 target of Nesh-SH3 isoform X11

Conserved Domains (2) summary

cd00063
Location:1532 → 1623

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247305.3 → XP_005247362.1 target of Nesh-SH3 isoform X44

Conserved Domains (2) summary

cd00063
Location:1442 → 1533

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247303.3 → XP_005247360.1 target of Nesh-SH3 isoform X41

Conserved Domains (2) summary

cd00063
Location:1470 → 1561

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512651.2 → XP_011510953.1 target of Nesh-SH3 isoform X33

Conserved Domains (2) summary

cd00063
Location:1490 → 1581

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247296.3 → XP_005247353.1 target of Nesh-SH3 isoform X26

Conserved Domains (2) summary

cd00063
Location:1510 → 1601

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247294.3 → XP_005247351.1 target of Nesh-SH3 isoform X21

Conserved Domains (2) summary

cd00063
Location:1518 → 1609

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247284.3 → XP_005247341.1 target of Nesh-SH3 isoform X4

Conserved Domains (2) summary

cd00063
Location:1538 → 1629

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247302.3 → XP_005247359.1 target of Nesh-SH3 isoform X35

Conserved Domains (2) summary

cd00063
Location:1489 → 1580

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512649.2 → XP_011510951.1 target of Nesh-SH3 isoform X27

Conserved Domains (2) summary

cd00063
Location:1509 → 1600

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_017006107.2 → XP_016861596.1 target of Nesh-SH3 isoform X36
XM_011512644.2 → XP_011510946.1 target of Nesh-SH3 isoform X17

Conserved Domains (2) summary

cd00063
Location:1529 → 1620

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512639.2 → XP_011510941.1 target of Nesh-SH3 isoform X7

Conserved Domains (2) summary

cd00063
Location:1537 → 1628

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247285.3 → XP_005247342.1 target of Nesh-SH3 isoform X6

Conserved Domains (2) summary

cd00063
Location:1537 → 1628

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247298.3 → XP_005247355.1 target of Nesh-SH3 isoform X28

Conserved Domains (2) summary

cd00063
Location:1509 → 1600

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_011512645.2 → XP_011510947.1 target of Nesh-SH3 isoform X18

Conserved Domains (2) summary

cd00063
Location:1529 → 1620

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_017006105.2 → XP_016861594.1 target of Nesh-SH3 isoform X5
XM_017006106.2 → XP_016861595.1 target of Nesh-SH3 isoform X13
XM_005247287.3 → XP_005247344.1 target of Nesh-SH3 isoform X8

Conserved Domains (2) summary

cd00063
Location:1535 → 1626

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247293.3 → XP_005247350.1 target of Nesh-SH3 isoform X20

Conserved Domains (2) summary

cd00063
Location:1521 → 1612

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247301.3 → XP_005247358.1 target of Nesh-SH3 isoform X34

Conserved Domains (2) summary

cd00063
Location:1490 → 1581

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_006713569.3 → XP_006713632.1 target of Nesh-SH3 isoform X30

Conserved Domains (2) summary

cd00063
Location:1506 → 1597

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247291.3 → XP_005247348.1 target of Nesh-SH3 isoform X15

Conserved Domains (2) summary

cd00063
Location:1531 → 1622

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247290.3 → XP_005247347.1 target of Nesh-SH3 isoform X14

Conserved Domains (2) summary

cd00063
Location:1532 → 1623

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:123 → 211

fn3; Fibronectin type III domain
XM_005247309.2 → XP_005247366.1 target of Nesh-SH3 isoform X47

Conserved Domains (1) summary

cd00063
Location:1259 → 1350

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...