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Conserved domains on  [gi|1770726425|ref|NP_056244|]
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target of Nesh-SH3 isoform 5 precursor [Homo sapiens]

Protein Classification

FN3 domain-containing protein( domain architecture ID 13885377)

FN3 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 477-789 2.69e-12

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 71.26  E-value: 2.69e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  477 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 548
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  549 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 618
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  619 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSthptKKPGTR 698
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEE----ERTFFH 761

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  699 RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITtpPLRSTPRPTGTplerietdikQPTVPASGEELENI----TD 774
Cdd:PTZ00449   762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDS--PSEHEDKPPGD----------HPSLPKKRHRLDGLalstTD 829

                          330
                   ....*....|....*.
gi 1770726425  775 FSSSPTR-ETDPLGKP 789
Cdd:PTZ00449   830 LESDAGRiAKDASGKI 845
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 832-923 9.25e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  832 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 909
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 1770726425  910 LGEGPVSNTVAFST 923
Cdd:cd00063     80 GGESPPSESVTVTT 93
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 257-591 2.33e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 65.34  E-value: 2.33e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  337 RSTKPTTSSALDVSETTLASSEKPwiVPTAKISEDSKVLQPqTATYDVFSSPTTSdepeisdsytatsdrildsIPPKTS 416
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLP--SPWDPADPPAAVLAP-AAALPPAASPAGP-------------------LPPPTS 2833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  417 RTLEQPRATLAPSETPFVPQKLEIFTSPEMQptTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPT 496
Cdd:PHA03247  2834 AQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR--RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQ 2910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  497 WTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 576
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990

                          330
                   ....*....|....*
gi 1770726425  577 PKDVLLPHKPYPEVS 591
Cdd:PHA03247  2991 SSTPPLTGHSLSRVS 3005
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 117-195 1.07e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


:

Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.07e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425   117 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 192
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 1770726425   193 GVK 195
Cdd:smart00060   73 RVR 75
 
Name Accession Description Interval E-value
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 477-789 2.69e-12

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 71.26  E-value: 2.69e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  477 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 548
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  549 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 618
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  619 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSthptKKPGTR 698
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEE----ERTFFH 761

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  699 RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITtpPLRSTPRPTGTplerietdikQPTVPASGEELENI----TD 774
Cdd:PTZ00449   762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDS--PSEHEDKPPGD----------HPSLPKKRHRLDGLalstTD 829

                          330
                   ....*....|....*.
gi 1770726425  775 FSSSPTR-ETDPLGKP 789
Cdd:PTZ00449   830 LESDAGRiAKDASGKI 845
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 832-923 9.25e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  832 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 909
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 1770726425  910 LGEGPVSNTVAFST 923
Cdd:cd00063     80 GGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 257-591 2.33e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 65.34  E-value: 2.33e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  337 RSTKPTTSSALDVSETTLASSEKPwiVPTAKISEDSKVLQPqTATYDVFSSPTTSdepeisdsytatsdrildsIPPKTS 416
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLP--SPWDPADPPAAVLAP-AAALPPAASPAGP-------------------LPPPTS 2833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  417 RTLEQPRATLAPSETPFVPQKLEIFTSPEMQptTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPT 496
Cdd:PHA03247  2834 AQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR--RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQ 2910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  497 WTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 576
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990

                          330
                   ....*....|....*
gi 1770726425  577 PKDVLLPHKPYPEVS 591
Cdd:PHA03247  2991 SSTPPLTGHSLSRVS 3005
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 833-913 2.11e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.23  E-value: 2.11e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425   833 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 910
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 1770726425   911 GEG 913
Cdd:smart00060   81 GEG 83
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 310-577 9.32e-08

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 56.12  E-value: 9.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  310 ALPAESKTPEVEKISArPTTVTPETvPRSTKPTTSSALDVSETTLASSEKPWIVPT-AKISEDSKVLQPQTATYDVFSS- 387
Cdd:pfam17823  129 SLPAAIAALPSEAFSA-PRAAACRA-NASAAPRAAIAAASAPHAASPAPRTAASSTtAASSTTAASSAPTTAASSAPATl 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  388 -PTTSDEPEISDSYTATSDRILDSIPPKTS--RTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPK 464
Cdd:pfam17823  207 tPARGISTAATATGHPAAGTALAAVGNSSPaaGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHM 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  465 RRPRPKPPRTKPERTTSAGTIT------PKISKSPEPTwttPAPGKTQFISLKPKIPLSPE---VTHTKPAPKQTPRAP- 534
Cdd:pfam17823  287 PSDTMARNPAAPMGAQAQGPIIqvstdqPVHNTAGEPT---PSPSNTTLEPNTPKSVASTNlavVTTTKAQAKEPSASPv 363

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1770726425  535 PKPKTSPRPRI----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 577
Cdd:pfam17823  364 PVLHTSMIPEVeatsPTTQPSPLLPTQGAAGPGILLAPEQVATEATA 410
fn3 pfam00041
Fibronectin type III domain;
833-916 7.99e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 45.10  E-value: 7.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  833 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 909
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 1770726425  910 LGEGPVS 916
Cdd:pfam00041   79 GGEGPPS 85
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 322-694 2.84e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.03  E-value: 2.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  322 KISARPTTVTPETVpRSTKPTTSSALdvseTTLASSekpwiVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYT 401
Cdd:pfam17823  113 RALAAAASSSPSSA-AQSLPAAIAAL----PSEAFS-----APRAAACRANASAAPRAAIAAASAPHAASPAPRTAASST 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  402 ATSDRILDSIPPKTSRTLEQPrATLAPSeTPFVPQKLEIFTsPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 481
Cdd:pfam17823  183 TAASSTTAASSAPTTAASSAP-ATLTPA-RGISTAATATGH-PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAA 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  482 AGTIT--PKISKSPEPTWTTPAPGKTqfislkpkiplspevthtkpAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPqrvt 559
Cdd:pfam17823  260 AGTVAsaAGTINMGDPHARRLSPAKH--------------------MPSDTMARNPAAPMGAQAQGPIIQVSTDQP---- 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  560 akpktspspeVSYTTPAPKdvllphkpypevsqsePAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPF----TT 635
Cdd:pfam17823  316 ----------VHNTAGEPT----------------PSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVpvlhTS 369

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726425  636 KIPRTTELAKTTQAPHRFYTTvrpRTSDkphirPGVKQAPRPSGADRNVSVDSTHPTKK 694
Cdd:pfam17823  370 MIPEVEATSPTTQPSPLLPTQ---GAAG-----PGILLAPEQVATEATAGTASAGPTPR 420
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
827-971 9.63e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.53  E-value: 9.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  827 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 904
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726425  905 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 971
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 117-195 1.07e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.07e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425   117 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 192
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 1770726425   193 GVK 195
Cdd:smart00060   73 RVR 75
fn3 pfam00041
Fibronectin type III domain;
116-195 1.11e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 192
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 1770726425  193 GVK 195
Cdd:pfam00041   72 RVQ 74
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
624-928 1.23e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.15  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  624 ETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP 703
Cdd:COG3401     23 VNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGS 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  704 PRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 783
Cdd:COG3401    103 VGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVAT 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  784 DPLGKPRFKGPHVRYIQKPDNS----PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLND 859
Cdd:COG3401    183 TSLTVTSTTLVDGGGDIEPGTTyyyrVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTES 259

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  860 TVTEYEvISRENGSfSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 928
Cdd:COG3401    260 DATGYR-VYRSNSG-DGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 116-195 3.66e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.56  E-value: 3.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  116 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 193
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                   ..
gi 1770726425  194 VK 195
Cdd:cd00063     74 VR 75
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 486-636 4.49e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 4.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  486 TPKISKSPEPTwtTPAPgKTQFISLKPKIPLSPEVTHTKPAPKQTPRaPPKPKTSPRPRIPQTQPVPkvpQRVTAKPKTS 565
Cdd:NF033839   382 TPKPEVKPQPE--KPKP-EVKPQPEKPKPEVKPQPEKPKPEVKPQPE-KPKPEVKPQPEKPKPEVKP---QPEKPKPEVK 454

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1770726425  566 PSPEvsytTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTK 636
Cdd:NF033839   455 PQPE----TPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQASTNEKATNK 521
 
Name Accession Description Interval E-value
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 477-789 2.69e-12

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 71.26  E-value: 2.69e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  477 ERTTSAGTITPKISKSPEPTWTT-----PAPGKTQFISLKPKIPLSPEVthtkPAPKQTPRAPPKPKTSPRPRIPQ---T 548
Cdd:PTZ00449   533 EHEDSKESDEPKEGGKPGETKEGevgkkPGPAKEHKPSKIPTLSKKPEF----PKDPKHPKDPEEPKKPKRPRSAQrptR 608

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  549 QPVPKVPQ--RVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMI--------SPSPSQEEL 618
Cdd:PTZ00449   609 PKSPKLPEllDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKPPFDPKFkekfyddyLDAAAKSKE 688

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  619 QTTLEETDQSTQEPFTTKIPRTTELAKTTQAPhrfYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSthptKKPGTR 698
Cdd:PTZ00449   689 TKTTVVLDESFESILKETLPETPGTPFTTPRP---LPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEE----ERTFFH 761

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  699 RPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPITtpPLRSTPRPTGTplerietdikQPTVPASGEELENI----TD 774
Cdd:PTZ00449   762 ETPADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDS--PSEHEDKPPGD----------HPSLPKKRHRLDGLalstTD 829

                          330
                   ....*....|....*.
gi 1770726425  775 FSSSPTR-ETDPLGKP 789
Cdd:PTZ00449   830 LESDAGRiAKDASGKI 845
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 832-923 9.25e-11

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 59.43  E-value: 9.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  832 NPPTNLTVVTVEgcPSFVILDWEKPLNDT--VTEYEVISRENGSFSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNP 909
Cdd:cd00063      2 SPPTNLRVTDVT--STSVTLSWTPPEDDGgpITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79

                           90
                   ....*....|....
gi 1770726425  910 LGEGPVSNTVAFST 923
Cdd:cd00063     80 GGESPPSESVTVTT 93
PHA03247 PHA03247
large tegument protein UL36; Provisional
 257-591 2.33e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 65.34  E-value: 2.33e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  257 DSAKSPEKAPlggvilvHLIIPGLNETTVKLPASLMFEISDALKTQLAKNETLALPAESKTPEVEKISARPTTVTPETVP 336
Cdd:PHA03247  2703 PPPPTPEPAP-------HALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  337 RSTKPTTSSALDVSETTLASSEKPwiVPTAKISEDSKVLQPqTATYDVFSSPTTSdepeisdsytatsdrildsIPPKTS 416
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLP--SPWDPADPPAAVLAP-AAALPPAASPAGP-------------------LPPPTS 2833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  417 RTLEQPRATLAPSETPFVPQKLEIFTSPEMQptTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTItPKISKSPEPT 496
Cdd:PHA03247  2834 AQPTAPPPPPGPPPPSLPLGGSVAPGGDVRR--RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQ 2910

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  497 WTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPA 576
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990

                          330
                   ....*....|....*
gi 1770726425  577 PKDVLLPHKPYPEVS 591
Cdd:PHA03247  2991 SSTPPLTGHSLSRVS 3005
PHA03247 PHA03247
large tegument protein UL36; Provisional
 324-691 4.51e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 4.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  324 SARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPT-AKISEDSKVLQPQTATYDvfSSPTTSDEPEISDSYTA 402
Cdd:PHA03247  2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPApGRVSRPRRARRLGRAAQA--SSPPQRPRRRAARPTVG 2693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  403 TSDRILDsiPPKTSRTLE-QPRATLAPSETPFVPQKL-EIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTT 480
Cdd:PHA03247  2694 SLTSLAD--PPPPPPTPEpAPHALVSATPLPPGPAAArQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAP 2771

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  481 SAGTITPKISKSPEPTWTTPAPGKTQFISlkPKIPLSPEVTHTKPAP----KQTPRAPPKPKTSPRPRIPQTQPVPkVPQ 556
Cdd:PHA03247  2772 PAAPAAGPPRRLTRPAVASLSESRESLPS--PWDPADPPAAVLAPAAalppAASPAGPLPPPTSAQPTAPPPPPGP-PPP 2848

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  557 RVTAKPKTSPSPEVSYTTP----APKDVLLPHKPYPEVSQSEPAPlETRGIPFIPMISPSPSQEELQTTLEETDQSTQEP 632
Cdd:PHA03247  2849 SLPLGGSVAPGGDVRRRPPsrspAAKPAAPARPPVRRLARPAVSR-STESFALPPDQPERPPQPQAPPPPQPQPQPPPPP 2927

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726425  633 FTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKP-----HIRPGVKQAPR---PSGAD-RNVSVDSTHP 691
Cdd:PHA03247  2928 QPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPqpwlgALVPGRVAVPRfrvPQPAPsREAPASSTPP 2995
PHA03247 PHA03247
large tegument protein UL36; Provisional
 422-790 1.28e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.57  E-value: 1.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  422 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPE--RTTSAGTITPKISKSPEPTWTT 499
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPS 2630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  500 PAPGKTQFISLKPKIPLSPEVTHTKPAPkqtPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKD 579
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAP---GRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT 2707

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  580 VLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIP-RTTELAKTTQAPHRfyTTVR 658
Cdd:PHA03247  2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPpAPAPPAAPAAGPPR--RLTR 2785

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  659 PRTSDKPHIRPGVKQAPRPSGADRNVSV-DSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNNVTGKPGSAGIISSGPIT-T 736
Cdd:PHA03247  2786 PAVASLSESRESLPSPWDPADPPAAVLApAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRrR 2865

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1770726425  737 PPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDfSSSPTRETDPLGKPR 790
Cdd:PHA03247  2866 PPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPD-QPERPPQPQAPPPPQ 2918
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 833-913 2.11e-08

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 52.23  E-value: 2.11e-08
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425   833 PPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV-ISRENGSFSGKNKSIQMTNQTFS-TVENLKPNTSYEFQVKPKNPL 910
Cdd:smart00060    3 PPSNLRVTDVT--STSVTLSWEPPPDDGITGYIVgYRVEYREEGSEWKEVNVTPSSTSyTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 1770726425   911 GEG 913
Cdd:smart00060   81 GEG 83
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 310-577 9.32e-08

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 56.12  E-value: 9.32e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  310 ALPAESKTPEVEKISArPTTVTPETvPRSTKPTTSSALDVSETTLASSEKPWIVPT-AKISEDSKVLQPQTATYDVFSS- 387
Cdd:pfam17823  129 SLPAAIAALPSEAFSA-PRAAACRA-NASAAPRAAIAAASAPHAASPAPRTAASSTtAASSTTAASSAPTTAASSAPATl 206

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  388 -PTTSDEPEISDSYTATSDRILDSIPPKTS--RTLEQPRATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPK 464
Cdd:pfam17823  207 tPARGISTAATATGHPAAGTALAAVGNSSPaaGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHM 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  465 RRPRPKPPRTKPERTTSAGTIT------PKISKSPEPTwttPAPGKTQFISLKPKIPLSPE---VTHTKPAPKQTPRAP- 534
Cdd:pfam17823  287 PSDTMARNPAAPMGAQAQGPIIqvstdqPVHNTAGEPT---PSPSNTTLEPNTPKSVASTNlavVTTTKAQAKEPSASPv 363

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1770726425  535 PKPKTSPRPRI----PQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAP 577
Cdd:pfam17823  364 PVLHTSMIPEVeatsPTTQPSPLLPTQGAAGPGILLAPEQVATEATA 410
PHA03247 PHA03247
large tegument protein UL36; Provisional
 386-854 9.24e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 9.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  386 SSPTTSDEPEISDSyTATSDRILDSIPPKTSRtleqPRATLAPSETPfvpqkleiftsPEMQPTTPAPQQTTSIPSTPKR 465
Cdd:PHA03247  2567 SVPPPRPAPRPSEP-AVTSRARRPDAPPQSAR----PRAPVDDRGDP-----------RGPAPPSPLPPDTHAPDPPPPS 2630

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  466 RPRPKPPRTKPERTTSAGTITPKISKSP---EPTWTTPAPGKTQFISLKPKIPLSPEVTHT---------KPAPKQTPRA 533
Cdd:PHA03247  2631 PSPAANEPDPHPPPTVPPPERPRDDPAPgrvSRPRRARRLGRAAQASSPPQRPRRRAARPTvgsltsladPPPPPPTPEP 2710

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  534 PPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLET---RGIPFIPMIS 610
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgppRRLTRPAVAS 2790

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  611 PSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHrfyTTVRPRTSDKPhirPGVKQAPRPSGAdrnvSVDSTH 690
Cdd:PHA03247  2791 LSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPP---TSAQPTAPPPP---PGPPPPSLPLGG----SVAPGG 2860

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  691 PTKKPGTRRPplppRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELE 770
Cdd:PHA03247  2861 DVRRRPPSRS----PAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP 2936

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  771 NITDFSSSPTRETDPLGKPRfkgPHVRYIQKPDNSPCSITDSVKRFPkEEATEGNATSPPQNPPTNLTVVTVEGCPSFVI 850
Cdd:PHA03247  2937 PRPQPPLAPTTDPAGAGEPS---GAVPQPWLGALVPGRVAVPRFRVP-QPAPSREAPASSTPPLTGHSLSRVSSWASSLA 3012


                   ....
gi 1770726425  851 LDWE 854
Cdd:PHA03247  3013 LHEE 3016
fn3 pfam00041
Fibronectin type III domain;
833-916 7.99e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 45.10  E-value: 7.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  833 PPTNLTVVTVEgcPSFVILDWEKP--LNDTVTEYEVISRENGSFSGKNkSIQMTNQTFS-TVENLKPNTSYEFQVKPKNP 909
Cdd:pfam00041    2 APSNLTVTDVT--STSLTVSWTPPpdGNGPITGYEVEYRPKNSGEPWN-EITVPGTTTSvTLTGLKPGTEYEVRVQAVNG 78


                   ....*..
gi 1770726425  910 LGEGPVS 916
Cdd:pfam00041   79 GGEGPPS 85
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 322-694 2.84e-05

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 48.03  E-value: 2.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  322 KISARPTTVTPETVpRSTKPTTSSALdvseTTLASSekpwiVPTAKISEDSKVLQPQTATYDVFSSPTTSDEPEISDSYT 401
Cdd:pfam17823  113 RALAAAASSSPSSA-AQSLPAAIAAL----PSEAFS-----APRAAACRANASAAPRAAIAAASAPHAASPAPRTAASST 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  402 ATSDRILDSIPPKTSRTLEQPrATLAPSeTPFVPQKLEIFTsPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTS 481
Cdd:pfam17823  183 TAASSTTAASSAPTTAASSAP-ATLTPA-RGISTAATATGH-PAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAA 259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  482 AGTIT--PKISKSPEPTWTTPAPGKTqfislkpkiplspevthtkpAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPqrvt 559
Cdd:pfam17823  260 AGTVAsaAGTINMGDPHARRLSPAKH--------------------MPSDTMARNPAAPMGAQAQGPIIQVSTDQP---- 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  560 akpktspspeVSYTTPAPKdvllphkpypevsqsePAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPF----TT 635
Cdd:pfam17823  316 ----------VHNTAGEPT----------------PSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVpvlhTS 369

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726425  636 KIPRTTELAKTTQAPHRFYTTvrpRTSDkphirPGVKQAPRPSGADRNVSVDSTHPTKK 694
Cdd:pfam17823  370 MIPEVEATSPTTQPSPLLPTQ---GAAG-----PGILLAPEQVATEATAGTASAGPTPR 420
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 511-606 4.04e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 47.63  E-value: 4.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  511 KPKIPLSPEVTHTKPAPKQTPraPPKPKTSPRpripqtQPVPKVPQRVTAKPKTSPSPEvSYTTPAPKDVLLPHKPYPEV 590
Cdd:PRK14954   375 RNDGGVAPSPAGSPDVKKKAP--EPDLPQPDR------HPGPAKPEAPGARPAELPSPA-SAPTPEQQPPVARSAPLPPS 445

                           90
                   ....*....|....*.
gi 1770726425  591 SQSEPAPLETRGIPFI 606
Cdd:PRK14954   446 PQASAPRNVASGKPGV 461
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 372-678 4.54e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.77  E-value: 4.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  372 SKVLQPQTATYDVFSSPTTSDEP--------EISDSYTATSDRILDSIP-PKTSRTLEQPRATLAPSETPFVPQKLeIFT 442
Cdd:PRK10263   297 NRATQPEYDEYDPLLNGAPITEPvavaaaatTATQSWAAPVEPVTQTPPvASVDVPPAQPTVAWQPVPGPQTGEPV-IAP 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  443 SPEM---QPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEptWTTPAPGKTQFISLKPKIPLSPE 519
Cdd:PRK10263   376 APEGypqQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQ--QPYYAPAPEQPVAGNAWQAEEQQ 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  520 vTHTKPAPKQTPRappKPKTSPRPRIPQTQPVPKVPQrvtaKPKTSPSPEVSYTTPAPKdvllPHKPYPEVSQSEPAPLE 599
Cdd:PRK10263   454 -STFAPQSTYQTE---QTYQQPAAQEPLYQQPQPVEQ----QPVVEPEPVVEETKPARP----PLYYFEEVEEKRARERE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  600 TRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFT---TKIPRTTELAKTTQAPHRFYTTVRPRTS------DKPHIRPG 670
Cdd:PRK10263   522 QLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEaaaAVSPLASGVKKATLATGAAATVAAPVFSlansggPRPQVKEG 601


                   ....*....
gi 1770726425  671 V-KQAPRPS 678
Cdd:PRK10263   602 IgPQLPRPK 610
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
827-971 9.63e-05

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.53  E-value: 9.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  827 TSPPQnPPTNLTVVTVEgcPSFVILDWEKPLNDTVTEYEV--ISRENGSFSGKNKSIqmtNQTFSTVENLKPNTSYEFQV 904
Cdd:COG3401    324 LTPPA-APSGLTATAVG--SSSITLSWTASSDADVTGYNVyrSTSGGGTYTKIAETV---TTTSYTDTGLTPGTTYYYKV 397

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1770726425  905 KPKNPLG-EGPVSNTVAFSTESADPRVSEPVSAGRDAIWTERPFNSDSYSECKGKQYVKRTWYKKFVG 971
Cdd:COG3401    398 TAVDAAGnESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTG 465
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 117-195 1.07e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.83  E-value: 1.07e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425   117 PLQLVVGTLTPSSVFLSWgflinphhdwtLPSHCPNDRFYTIRYREKDKEKKWIFQICPA----TETIVENLKPNTVYEF 192
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSW-----------EPPPDDGITGYIVGYRVEYREEGSEWKEVNVtpssTSYTLTGLKPGTEYEF 72


                    ...
gi 1770726425   193 GVK 195
Cdd:smart00060   73 RVR 75
fn3 pfam00041
Fibronectin type III domain;
116-195 1.11e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 42.02  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  116 KPLQLVVGTLTPSSVFLSWgflinphhdwTLPSHCPND-RFYTIRYREKDKEKKWIFQICPATET--IVENLKPNTVYEF 192
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSW----------TPPPDGNGPiTGYEVEYRPKNSGEPWNEITVPGTTTsvTLTGLKPGTEYEV 71


                   ...
gi 1770726425  193 GVK 195
Cdd:pfam00041   72 RVQ 74
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 478-594 1.21e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 45.96  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  478 RTTSAGT-------ITPKISKSPEPTWTTPAPGktqfislkpkiplSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQP 550
Cdd:PRK14950   342 RTTSYGQlplelavIEALLVPVPAPQPAKPTAA-------------APSPVRPTPAPSTRPKAAAAANIPPKEPVRETAT 408

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1770726425  551 VPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSE 594
Cdd:PRK14950   409 PPPVPPRPVAPPVPHTPESAPKLTRAAIPVDEKPKYTPPAPPKE 452
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
624-928 1.23e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 46.15  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  624 ETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLP 703
Cdd:COG3401     23 VNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGS 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  704 PRPTHPRRKPLPPNNVTGKPGSAGIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRET 783
Cdd:COG3401    103 VGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVAT 182

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  784 DPLGKPRFKGPHVRYIQKPDNS----PCSITDSVKRFPKEEATEGNATSPPqNPPTNLTVVTVEgcPSFVILDWEKPLND 859
Cdd:COG3401    183 TSLTVTSTTLVDGGGDIEPGTTyyyrVAATDTGGESAPSNEVSVTTPTTPP-SAPTGLTATADT--PGSVTLSWDPVTES 259

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  860 TVTEYEvISRENGSfSGKNKSIQMTNQTFSTVENLKPNTSYEFQVKPKNPLG-EGPVSNTVAFSTESADP 928
Cdd:COG3401    260 DATGYR-VYRSNSG-DGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPP 327
DUF4813 pfam16072
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ...
 493-623 2.72e-04

Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.


Pssm-ID: 435117 [Multi-domain]  Cd Length: 288  Bit Score: 44.36  E-value: 2.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  493 PEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSY 572
Cdd:pfam16072  146 PGSVTTTSAGSGTTVINAGGQQPAAPAAPAYPVAPAAYPAQAPAAAPAPAPGAPQTPLAPLNPVAAAPAAAAGAAAAPVV 225

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1770726425  573 TTPAPKDVlLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLE 623
Cdd:pfam16072  226 AAAAPAAA-APPPPAPAAPPADAAPPAPGGIICVPVRVPEPDPKDATKTIE 275
PHA03378 PHA03378
EBNA-3B; Provisional
 312-555 2.85e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 45.06  E-value: 2.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  312 PAESKTPEVEKISARPTTVTPETVPRstkPTTSSALDVSETTLASSEKPWIVPTAKISEDSKVLQPQTATYDVFSSPTTS 391
Cdd:PHA03378   576 PLTSPTTSQLASSAPSYAQTPWPVPH---PSQTPEPPTTQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTPH 652

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  392 DEPEISDSYTATSDRILDSIPPKTSRTleQPRATLAPSETPfvpqkleifTSPEMQPTTPAPQQTTSIPSTPKRRPRPKP 471
Cdd:PHA03378   653 QPPQVEITPYKPTWTQIGHIPYQPSPT--GANTMLPIQWAP---------GTMQPPPRAPTPMRPPAAPPGRAQRPAAAT 721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  472 PRTKPERTTSAGTITPKISKSPEPTwTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRiPQTQPV 551
Cdd:PHA03378   722 GRARPPAAAPGRARPPAAAPGRARP-PAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGA-PTPQPP 799


                   ....
gi 1770726425  552 PKVP 555
Cdd:PHA03378   800 PQAG 803
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 116-195 3.66e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 40.56  E-value: 3.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  116 KPLQLVVGTLTPSSVFLSWgfliNPHHDWTLPSHcpndrFYTIRYREKDKE--KKWIFQICPATETIVENLKPNTVYEFG 193
Cdd:cd00063      3 PPTNLRVTDVTSTSVTLSW----TPPEDDGGPIT-----GYVVEYREKGSGdwKEVEVTPGSETSYTLTGLKPGTEYEFR 73


                   ..
gi 1770726425  194 VK 195
Cdd:cd00063     74 VR 75
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 486-636 4.49e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 4.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  486 TPKISKSPEPTwtTPAPgKTQFISLKPKIPLSPEVTHTKPAPKQTPRaPPKPKTSPRPRIPQTQPVPkvpQRVTAKPKTS 565
Cdd:NF033839   382 TPKPEVKPQPE--KPKP-EVKPQPEKPKPEVKPQPEKPKPEVKPQPE-KPKPEVKPQPEKPKPEVKP---QPEKPKPEVK 454

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1770726425  566 PSPEvsytTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTK 636
Cdd:NF033839   455 PQPE----TPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQASTNEKATNK 521
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 312-694 6.71e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 6.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  312 PAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASSEKPWIVPTakisedskvlqPQtatydvfsSPTTS 391
Cdd:PTZ00449   585 PKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPP-----------PQ--------RPSSP 645

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  392 DEPEISDSytatsdrildsipPKTSRTLEQPRAtlapsetPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPrpkp 471
Cdd:PTZ00449   646 ERPEGPKI-------------IKSPKPPKSPKP-------PFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFES---- 701

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  472 prtkperttsagTITPKISKSPEPTWTTPAPgktqfisLKPKIPLSPEVTHTKP----APKQTPRAPPKPKTSPRPRIPQ 547
Cdd:PTZ00449   702 ------------ILKETLPETPGTPFTTPRP-------LPPKLPRDEEFPFEPIgdpdAEQPDDIEFFTPPEEERTFFHE 762

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  548 TQPVPKVPQRVTAKPKTspsPEVSYTTPAPKDvllPHKPYPEVSQSEPAPLETRgiPFIPMISPSPSQEELQTTLEETDQ 627
Cdd:PTZ00449   763 TPADTPLPDILAEEFKE---EDIHAETGEPDE---AMKRPDSPSEHEDKPPGDH--PSLPKKRHRLDGLALSTTDLESDA 834

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1770726425  628 STQEPFTTKIPRTTELAKTTQAphrfYTTVRprtsDKPHIRPgvkQAPRPSGADRNVSVD--STHPTKK 694
Cdd:PTZ00449   835 GRIAKDASGKIVKLKRSKSFDD----LTTVE----EAEEMGA---EARKIVVDDDGTEADdeDTHPPEE 892
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
449-662 7.71e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.71  E-value: 7.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  449 TTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPK 528
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  529 QTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPevSYTTPAPKDVLLPHKPYPEVSQSEPApletrgipfipm 608
Cdd:PRK12323   452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP--ADDDPPPWEELPPEFASPAPAQPDAA------------ 517

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1770726425  609 ispsPSQEELQTTLEETDQSTQEPFTTKIPRTT--ELAKTTQAPHRFYTTVRPRTS 662
Cdd:PRK12323   518 ----PAGWVAESIPDPATADPDDAFETLAPAPAaaPAPRAAAATEPVVAPRPPRAS 569
PRK11633 PRK11633
cell division protein DedD; Provisional
 490-578 1.18e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 41.53  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  490 SKSPEPTWTTPAPGKTQFISLKPKIPLSPEVThtkPAPKQTPRAPPKPKtsPRPRiPQTQPVPKVPQRVTAKPKTSPSPE 569
Cdd:PRK11633    65 TQPPEGAAEAVRAGDAAAPSLDPATVAPPNTP---VEPEPAPVEPPKPK--PVEK-PKPKPKPQQKVEAPPAPKPEPKPV 138


                   ....*....
gi 1770726425  570 VSyTTPAPK 578
Cdd:PRK11633   139 VE-EKAAPT 146
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 422-807 2.53e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  422 PRATLAPSETPFVPQKLEIFTSPEMQPTTPAP-QQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTP 500
Cdd:PHA03307    49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPaNESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPP 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  501 APGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPqtqPVPKVPQrvTAKPKTSPSPEVSYTTPAPKDV 580
Cdd:PHA03307   129 SPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAL---PLSSPEE--TARAPSSPPAEPPPSTPPAAAS 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  581 LLPHKPYPEVS--QSEPAPLETR----GIPFIPMIS-PSPSQEELQTTLEETDQSTQEPFTTKIPRTTELA-------KT 646
Cdd:PHA03307   204 PRPPRRSSPISasASSPAPAPGRsaadDAGASSSDSsSSESSGCGWGPENECPLPRPAPITLPTRIWEASGwngpssrPG 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  647 TQAPHrfyTTVRPRTSDKPHIRPGVKQAPRPSGADRNVSVDSTHPTKKPGTRRPPLPPRPTHPRRKPLPPNnvTGKPGSA 726
Cdd:PHA03307   284 PASSS---SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSP--SPSRPPP 358

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  727 GIISSGPITTPPLRSTPRPTGTPLERIETDIKQPTVPASGEELENITDFSSSPTRETDPLGKPRFKGPHVRYiqkPDNSP 806
Cdd:PHA03307   359 PADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY---PLLTP 435


                   .
gi 1770726425  807 C 807
Cdd:PHA03307   436 S 436
PHA03378 PHA03378
EBNA-3B; Provisional
 490-749 2.54e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.98  E-value: 2.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  490 SKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPriPQTQPVPkvpqrvtakpktspsPE 569
Cdd:PHA03378   555 STEPVHDQLLPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEP--PTTQSHI---------------PE 617

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  570 vsytTPAPKDVLLPHKPYPevsqsePAPLETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAK---- 645
Cdd:PHA03378   618 ----TSAPRQWPMPLRPIP------MRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQPSPTGANTmlpi 687

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  646 -----TTQAPHRFYTTVRPrtsdkPHIRPGVKQAPRPSgadrnvsvdsthPTKKPGTRRPPLPPRPTHPRRKPLPPNnvT 720
Cdd:PHA03378   688 qwapgTMQPPPRAPTPMRP-----PAAPPGRAQRPAAA------------TGRARPPAAAPGRARPPAAAPGRARPP--A 748

                          250       260       270
                   ....*....|....*....|....*....|
gi 1770726425  721 GKPGSAGIISSGPITTPPLRSTP-RPTGTP 749
Cdd:PHA03378   749 AAPGRARPPAAAPGRARPPAAAPgAPTPQP 778
PHA03369 PHA03369
capsid maturational protease; Provisional
 496-588 2.70e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 41.91  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  496 TWTTPAPGKTQFISLKPKIPLSPEvTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPkVPQRVTAKPKTSPSPEVSYTTP 575
Cdd:PHA03369   350 TASLTAPSRVLAAAAKVAVIAAPQ-THTGPADRQRPQRPDGIPYSVPARSPMTAYPP-VPQFCGDPGLVSPYNPQSPGTS 427

                           90
                   ....*....|...
gi 1770726425  576 APKDVLLPHKPYP 588
Cdd:PHA03369   428 YGPEPVGPVPPQP 440
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 448-680 2.95e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.45  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  448 PTTPAPQQTTSIPSTPKRRprpkpprtkpERTTSAGTITPKISKSPEPTWTTPAPGKTqfislkpkiPLSPEVTHTKPAP 527
Cdd:PLN03209   312 PLTPMEELLAKIPSQRVPP----------KESDAADGPKPVPTKPVTPEAPSPPIEEE---------PPQPKAVVPRPLS 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  528 KQTPRAPPKPKTSPRPRIPQTQPVPKVPQRVTAKPKTSPSPEVSYTTPApkdvllphkpypeVSQSEPAPLETRGI---- 603
Cdd:PLN03209   373 PYTAYEDLKPPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASN-------------VPEVEPAQVEAKKTrpls 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  604 PFI------PMISPSPSQEE-LQTTLEETDQSTQEPFTTKIPRTTELAKTTQA------PHRFYTTVRPRTSDKPhIRPG 670
Cdd:PLN03209   440 PYAryedlkPPTSPSPTAPTgVSPSVSSTSSVPAVPDTAPATAATDAAAPPPAnmrplsPYAVYDDLKPPTSPSP-AAPV 518

                          250
                   ....*....|
gi 1770726425  671 VKQAPRPSGA 680
Cdd:PLN03209   519 GKVAPSSTNE 528
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 490-578 2.95e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 41.37  E-value: 2.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  490 SKSPEPTWTTPAPGKT-----QFISLKPKIPLSP-------EVTHTKPAPKQTPRAPPKPKTSPRPRIPQTQPVPKVPQR 557
Cdd:COG3266    255 LKAPSQASSASAPATTslgeqQEVSLPPAVAAQPaaaaaaqPSAVALPAAPAAAAAAAAPAEAAAPQPTAAKPVVTETAA 334

                           90       100
                   ....*....|....*....|.
gi 1770726425  558 VTAkpktsPSPEVSYTTPAPK 578
Cdd:COG3266    335 PAA-----PAPEAAAAAAAPA 350
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 310-692 3.01e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.83  E-value: 3.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  310 ALPAESKTPEVEKISARPTTVTPETVPRSTKPTTSSALDVSETTLASsekpwivPTAKISEDSKVLQPQTATYDVFSSPT 389
Cdd:pfam05109  395 GLGTAPKTLIITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAA-------PNTTTGLPSSTHVPTNLTAPASTGPT 467

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  390 TSDEPEISDSYTATSDRILDSIPPKTsrtleqPRATLAPSETPFVpqkleifTSPEMQPTTPAPQQTTSIPSTPKRRPRP 469
Cdd:pfam05109  468 VSTADVTSPTPAGTTSGASPVTPSPS------PRDNGTESKAPDM-------TSPTSAVTTPTPNATSPTPAVTTPTPNA 534

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  470 KPPRTKPERTTSAGTITPKISKSPEPTWTTPAPGKTqfisLKPKIPLSPEVTHTKPAPKQTprAPPKPKTSPRPRIPQ-- 547
Cdd:pfam05109  535 TSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNAT----IPTLGKTSPTSAVTTPTPNAT--SPTVGETSPQANTTNht 608

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  548 ----------TQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRGIPF----IPMISPSP 613
Cdd:pfam05109  609 lggtsstpvvTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTggenITQVTPAS 688

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  614 SqeelQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTT--VRPRTSDKPHIRPGVKQA---PRPSGADRNVSVDS 688
Cdd:pfam05109  689 T----STHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTkgTPPKNATSPQAPSGQKTAvptVTSTGGKANSTTGG 764


                   ....
gi 1770726425  689 THPT 692
Cdd:pfam05109  765 KHTT 768
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
424-613 3.51e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 3.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  424 ATLAPSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITPKISKSPEPTWTTPAPG 503
Cdd:PRK12323   372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  504 KTqfislkpkiPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIP--QTQPVPKVPQRVTAKPKTSPSPEVSYTTPAPKDVL 581
Cdd:PRK12323   452 PA---------PAAAPAAAARPAAAGPRPVAAAAAAAPARAAPaaAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWV 522

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1770726425  582 LPHKPYPEVSQSEP-----------APLETRGIPFIPMISPSP 613
Cdd:PRK12323   523 AESIPDPATADPDDafetlapapaaAPAPRAAAATEPVVAPRP 565
Orthopox_A5L pfam06193
Orthopoxvirus A5L protein-like; This family includes several Orthopoxvirus A5L proteins. The ...
 477-642 3.94e-03

Orthopoxvirus A5L protein-like; This family includes several Orthopoxvirus A5L proteins. The vaccinia virus WR A5L open reading frame (corresponding to open reading frame A4L in vaccinia virus Copenhagen) encodes an immunodominant late protein found in the core of the vaccinia virion. The A5 protein appears to be required for the immature virion to form the brick-shaped intracellular mature virion.


Pssm-ID: 283778 [Multi-domain]  Cd Length: 216  Bit Score: 39.96  E-value: 3.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  477 ERTTSAGTITPKISKSPEPTWTTPAPGKTQFISLKPKIP--LSPEVTHTKP-APKQTPRAPPKPKTSPRP-RIPQTQPVP 552
Cdd:pfam06193   13 EDATAKNSAYYSEEDDLDILGKKDEAGEIGFESQERQYQqqLIEQLAKDNMlAASRQPIQPLQPTIHITPiEIPTPAPTP 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  553 KVPQRVTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPLETRgIPFIPMISPSP---SQEELQTTLEETDQST 629
Cdd:pfam06193   93 KPRQQELGTPSTSCTQNSDASIACSTDIVTPPQPPIVATVCTPTPTDGR-ICTTADQNPNPgatIQKELDNMALKDLMSS 171

                          170
                   ....*....|...
gi 1770726425  630 QEPFTTKIPRTTE 642
Cdd:pfam06193  172 VEKDMCQLQAESE 184
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 480-581 4.97e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 4.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  480 TSAGTITPKiSKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPR--APPKPKTSPRPRIPQTQPVPKVPQR 557
Cdd:PRK14950   364 PAPQPAKPT-AAAPSPVRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRpvAPPVPHTPESAPKLTRAAIPVDEKP 442

                           90       100
                   ....*....|....*....|....
gi 1770726425  558 VTAKPktSPSPEVSYTTPAPKDVL 581
Cdd:PRK14950   443 KYTPP--APPKEEEKALIADGDVL 464
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 486-617 6.24e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.84  E-value: 6.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1770726425  486 TPKISKSPEPTWTTPA-PGKTQFISLKPKIPLSPEVTHTKPAPKQTPR---APPKPKTSPRPRIPQTQPvPKVPQRVTAK 561
Cdd:PRK10263   754 QPQQPVAPQQQYQQPQqPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQpqyQQPQQPVAPQPQYQQPQQ-PVAPQPQYQQ 832

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1770726425  562 PKTSPSpevsyttPAPKDVLLpHKPYPEVSQSEPAPLETRGIPFIPMISPSPSQEE 617
Cdd:PRK10263   833 PQQPVA-------PQPQDTLL-HPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVE 880
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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