3LPW,2NZI,1X5G,2EDY,2YUX,1X5H,2ED9,2YRZ,2GEE,1FNF,1FNH,1X5F,2X11,1TDQ,2ED8,2E7H,2ED7,2DJS,2EDX,3F7Q,3F7Q,1QR4


Conserved Protein Domain Family
FN3

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smart00060: FN3 
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Fibronectin type 3 domain
One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Statistics
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PSSM-Id: 214495
Aligned: 843 rows
Threshold Bit Score: 29.8901
Threshold Setting Gi: 194386326
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3LPW_A        103 PLPPGK---ITLMDVTRN--SVSLSWEKPEHdg---gsRILGYIVEMQTkg--------sdKWATCATVk---vTEATIT 163  human
Q63130       1022 RIFILS---LGRYTRKNe-vVVEFRWNKPKHen----gVLTKSEIFYHIskqsgtnkstedWVSVSVTpp---vMSFQLE 1090 Norway rat
EGB63025      122 vtPPAVqhlTAEVTADSGeyQVLARWDTPKVvkg--vsFLLRLTVTADDgs--------erLVSTARTTe----tTYRFT 187  Escherichia c...
NP_149090     217 ePVPPDh--LALRALGTS--SLQAFWN-SSEga---tsFHLMLTDLLGG------------TNTTAVIRqg--vSTHTFL 274  Norway rat
BAC28718      124 PLAPDN---LTLHTNVSDe--WLLTWNNLYPsnnllykDLISMVNISREdnp-------aeFIVYNVTYk---ePRLSFP 188  house mouse
XP_003261613   98 PRAPGN---LTVHTNVSDt--LLLTWSNPYPpdnylynHLTYAVNIWSEndp-------adFRIYNVTYl---ePSLRIA 162  White-cheeked...
NP_776784     161 PWAPEN---LTLRNLSEFq--LELSWSNRYLdhc-lehLVQYRSDRDRs------------WTEQSVDh----rHSFSLP 218  cattle
XP_543002     487 VHGPQN---VEIVDIRAR--QLTLQWEPFGYavt--rcHSYNLTVQYQYvfn------qqqYEAEEVIqt---sSHYTLR 550  dog
CAA65832      379 hEGPKG---LAFAEIQAR--QLTLQWEPLGYnvt--rcHTYTVSLCYHYtlgs-----shnQTIRECVKteqgvSRYTIK 446  human
XP_859402       1 MRGPRK---LEVVEVKSR--QITIRWEPFGYnvt--rcHSYNLTVHYCYqvgg-----qeqVREEVSWDtdnshPQHTIT 68   dog
Q63130       1022 RIFILS---LGRYTRKNe-vVVEFRWNKPKHen----gVLTKSEIFYHIskqsgtnkstedWVSVSVTpp---vMSFQLE 1090 Norway rat
EGB63025      122 vtPPAVqhlTAEVTADSGeyQVLARWDTPKVvkg--vsFLLRLTVTADDgs--------erLVSTARTTe----tTYRFT 187  Escherichia c...
NP_149090     217 ePVPPDh--LALRALGTS--SLQAFWN-SSEga---tsFHLMLTDLLGG------------TNTTAVIRqg--vSTHTFL 274  Norway rat
BAC28718      124 PLAPDN---LTLHTNVSDe--WLLTWNNLYPsnnllykDLISMVNISREdnp-------aeFIVYNVTYk---ePRLSFP 188  house mouse
XP_003261613   98 PRAPGN---LTVHTNVSDt--LLLTWSNPYPpdnylynHLTYAVNIWSEndp-------adFRIYNVTYl---ePSLRIA 162  White-cheeked...
NP_776784     161 PWAPEN---LTLRNLSEFq--LELSWSNRYLdhc-lehLVQYRSDRDRs------------WTEQSVDh----rHSFSLP 218  cattle
XP_543002     487 VHGPQN---VEIVDIRAR--QLTLQWEPFGYavt--rcHSYNLTVQYQYvfn------qqqYEAEEVIqt---sSHYTLR 550  dog
CAA65832      379 hEGPKG---LAFAEIQAR--QLTLQWEPLGYnvt--rcHTYTVSLCYHYtlgs-----shnQTIRECVKteqgvSRYTIK 446  human
XP_859402       1 MRGPRK---LEVVEVKSR--QITIRWEPFGYnvt--rcHSYNLTVHYCYqvgg-----qeqVREEVSWDtdnshPQHTIT 68   dog
3LPW_A        164 GLIQGEEYSFRVSAQNe--KGIS 184  human
Q63130       1091 AMSPGYIVSFQVRVFTs--KGPG 1111 Norway rat
EGB63025      188 QLALG-NYRLTVRAVn--aWGQQ 207  Escherichia coli M863
NP_149090     275 HLSPGTPHELKICASAgphQIWG 297  Norway rat
BAC28718      189 INILMSGVYYTARVRVr--SQIL 209  house mouse
XP_003261613  163 ASTLKSGISYRARVRAw--AQCY 183  White-cheeked Gibbon
NP_776784     219 SVDAQKLYTFRVRSRYn--PLCG 239  cattle
XP_543002     551 GLRPFMTIRLRLLLSNp--EGRM 571  dog
CAA65832      447 NLLPYRNVHVRLVLTNp--EGRK 467  human
XP_859402      69 NLSPYTNVSVKLILMNp--EGRK 89   dog
Q63130       1091 AMSPGYIVSFQVRVFTs--KGPG 1111 Norway rat
EGB63025      188 QLALG-NYRLTVRAVn--aWGQQ 207  Escherichia coli M863
NP_149090     275 HLSPGTPHELKICASAgphQIWG 297  Norway rat
BAC28718      189 INILMSGVYYTARVRVr--SQIL 209  house mouse
XP_003261613  163 ASTLKSGISYRARVRAw--AQCY 183  White-cheeked Gibbon
NP_776784     219 SVDAQKLYTFRVRSRYn--PLCG 239  cattle
XP_543002     551 GLRPFMTIRLRLLLSNp--EGRM 571  dog
CAA65832      447 NLLPYRNVHVRLVLTNp--EGRK 467  human
XP_859402      69 NLSPYTNVSVKLILMNp--EGRK 89   dog
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