U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp280d zinc finger protein 280D [ Mus musculus (house mouse) ]

Gene ID: 235469, updated on 26-Sep-2022

Summary

Official Symbol
Zfp280dprovided by MGI
Official Full Name
zinc finger protein 280Dprovided by MGI
Primary source
MGI:MGI:2384583
See related
Ensembl:ENSMUSG00000038535 AllianceGenome:MGI:2384583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Suhw4; ZNF634; Znf280d; A930005F02Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in early conceptus; nervous system; olfactory epithelium; oocyte; and retina. Orthologous to human ZNF280D (zinc finger protein 280D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 9.8), CNS E14 (RPKM 9.7) and 22 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Zfp280d in Genome Data Viewer
Location:
9; 9 D
Exon count:
27
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (72181900..72271061)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (72274618..72363779)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene 27188 Neighboring gene predicted gene, 25163 Neighboring gene ribosomal protein L27A pseudogene Neighboring gene ribosomal protein L7A pseudogene Neighboring gene predicted gene 27230 Neighboring gene cDNA sequence BC065403 Neighboring gene meiosis-specific nuclear structural protein 1 Neighboring gene testis expressed gene 9

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC36902

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 280D
Names
suppressor of hairy wing homolog 4

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001311105.1NP_001298034.1  zinc finger protein 280D isoform 2

    See identical proteins and their annotated locations for NP_001298034.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, which results in a frame-shift compared to variant 1. It encodes isoform 2, which is shorter than and has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK045173, AK146597, BB616601, BC079878, CT025608
    Consensus CDS
    CCDS81035.1
    UniProtKB/Swiss-Prot
    Q68FE8
    UniProtKB/TrEMBL
    V9GXP2
    Related
    ENSMUSP00000139250.2, ENSMUST00000183410.8
    Conserved Domains (2) summary
    sd00017
    Location:372393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:57241
    DUF4195; Domain of unknown function (DUF4195)
  2. NM_146224.5NP_666336.3  zinc finger protein 280D isoform 1

    See identical proteins and their annotated locations for NP_666336.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK146597, BB616601, BC079878, CT025608
    Consensus CDS
    CCDS40683.1
    UniProtKB/Swiss-Prot
    Q68FE8, Q8BI82
    Related
    ENSMUSP00000096175.3, ENSMUST00000098576.10
    Conserved Domains (3) summary
    sd00017
    Location:372393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:335369
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:57241
    DUF4195; Domain of unknown function (DUF4195)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    72181900..72271061
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511121.4XP_006511184.1  zinc finger protein 280D isoform X2

    Conserved Domains (2) summary
    sd00017
    Location:372393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:57236
    DUF4195; Domain of unknown function (DUF4195)
  2. XM_006511122.3XP_006511185.1  zinc finger protein 280D isoform X3

    Related
    ENSMUSP00000138970.2, ENSMUST00000184517.8
    Conserved Domains (2) summary
    sd00017
    Location:372393
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:57236
    DUF4195; Domain of unknown function (DUF4195)
  3. XM_036154909.1XP_036010802.1  zinc finger protein 280D isoform X4

    Conserved Domains (1) summary
    sd00017
    Location:132153
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_017313342.2XP_017168831.1  zinc finger protein 280D isoform X1

    UniProtKB/TrEMBL
    V9GWW1
    Related
    ENSMUSP00000138857.2, ENSMUST00000184036.8
    Conserved Domains (3) summary
    sd00017
    Location:347368
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:310344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:32211
    DUF4195; Domain of unknown function (DUF4195)
  5. XM_017313343.2XP_017168832.1  zinc finger protein 280D isoform X5

    Conserved Domains (1) summary
    sd00017
    Location:102123
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_030244338.1XP_030100198.1  zinc finger protein 280D isoform X4

    Conserved Domains (1) summary
    sd00017
    Location:132153
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_004935419.1 RNA Sequence

  2. XR_004935420.1 RNA Sequence

  3. XR_004935421.1 RNA Sequence