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Zfp62 zinc finger protein 62 [ Mus musculus (house mouse) ]

Gene ID: 22720, updated on 21-May-2024

Summary

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Official Symbol
Zfp62provided by MGI
Official Full Name
zinc finger protein 62provided by MGI
Primary source
MGI:MGI:99662
See related
Ensembl:ENSMUSG00000046311 AllianceGenome:MGI:99662
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; heart; limb; limb bud; and urinary system. Orthologous to human ZFP62 (ZFP62 zinc finger protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 6.2), CNS E14 (RPKM 4.9) and 21 other tissues See more
Orthologs
human all
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Genomic context

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See Zfp62 in Genome Data Viewer
Location:
11 B1.2; 11 29.23 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (49093556..49109643)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (49203261..49218816)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 2 subfamily O member 1 Neighboring gene butyrophilin-like 9 Neighboring gene STARR-seq mESC enhancer starr_29371 Neighboring gene STARR-seq mESC enhancer starr_29372 Neighboring gene predicted gene, 18583 Neighboring gene STARR-positive B cell enhancer ABC_E6976 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:49057557-49057744 Neighboring gene predicted gene, 51893 Neighboring gene STARR-positive B cell enhancer ABC_E195 Neighboring gene mannoside acetylglucosaminyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Differentiation dependent expression in muscle cells of ZT3, a novel zinc finger factor differentially expressed in embryonic and adult tissues. Polimeni M, et al. Mech Dev, 1996 Jan. PMID 8808410
  2. Genetic mapping of mouse heat shock protein genes Hsc4a to chromosome 11 and Hsc74 to chromosome 18 and two Hsc74 pseudogenes to chromosomes X and 8. Hunt CR, et al. Genomics, 1999 Mar 15. PMID 10087208
  3. Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens. Danciger M, et al. Genomics, 1995 Jul 1. PMID 7590745
  4. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
  5. A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Choi MY, et al. Development, 2006 Oct. PMID 16971476

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 62
Names
ZT3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024846.2 → NP_001020017.1  zinc finger protein 62 isoform 2

    See identical proteins and their annotated locations for NP_001020017.1

    Status: VALIDATED

    Source sequence(s)
    AK028351, AK048619, AL606829, BC065692, BE635021
    Consensus CDS
    CCDS24601.1
    UniProtKB/Swiss-Prot
    Q8C827
    Related
    ENSMUSP00000104820.2, ENSMUST00000109197.8
    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. NM_001362725.1 → NP_001349654.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. NM_001362726.1 → NP_001349655.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. NM_001362727.1 → NP_001349656.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. NM_001362728.1 → NP_001349657.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    Consensus CDS
    CCDS24601.1
    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. NM_001362729.1 → NP_001349658.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    Consensus CDS
    CCDS24601.1
    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. NM_001362730.1 → NP_001349659.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829, BE635021
    Consensus CDS
    CCDS24601.1
    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. NM_001362731.1 → NP_001349660.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK147890, AL606829, BE635021
    Consensus CDS
    CCDS24601.1
    Related
    ENSMUSP00000116045.2, ENSMUST00000136539.2
    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  9. NM_001425606.1 → NP_001412535.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1

  10. NM_001425607.1 → NP_001412536.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1

  11. NM_001425608.1 → NP_001412537.1  zinc finger protein 62 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL606829
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1

  12. NM_001425610.1 → NP_001412539.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829

  13. NM_001425611.1 → NP_001412540.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829

  14. NM_001425612.1 → NP_001412541.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829
    Related
    ENSMUSP00000104821.2, ENSMUST00000109198.8

  15. NM_001425613.1 → NP_001412542.1  zinc finger protein 62 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL606829

  16. NM_009562.4 → NP_033588.2  zinc finger protein 62 isoform 1

    See identical proteins and their annotated locations for NP_033588.2

    Status: VALIDATED

    Source sequence(s)
    AL606829
    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    49093556..49109643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245950.2 → XP_030101810.1  zinc finger protein 62 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_036156643.1 → XP_036012536.1  zinc finger protein 62 isoform X1

    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  3. XM_030245946.2 → XP_030101806.1  zinc finger protein 62 isoform X1

    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  4. XM_036156648.1 → XP_036012541.1  zinc finger protein 62 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  5. XM_036156647.1 → XP_036012540.1  zinc finger protein 62 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  6. XM_036156644.1 → XP_036012537.1  zinc finger protein 62 isoform X1

    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]

  7. XM_030245947.2 → XP_030101807.1  zinc finger protein 62 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:430 → 843
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:372 → 451
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:210 → 230
    ZF_C2H2; C2H2 Zn finger [structural motif]

  8. XM_036156646.1 → XP_036012539.1  zinc finger protein 62 isoform X1

    UniProtKB/Swiss-Prot
    Q3U3H0, Q62510, Q8BT00, Q8C2S6, Q8C827, Q8R5D1
    Conserved Domains (3) summary
    COG5048
    Location:437 → 850
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:379 → 458
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:217 → 237
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C827.1 GenPept UniProtKB/Swiss-Prot:Q8C827

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