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ZFP62 ZFP62 zinc finger protein [ Homo sapiens (human) ]

Gene ID: 643836, updated on 13-Mar-2020

Summary

Official Symbol
ZFP62provided by HGNC
Official Full Name
ZFP62 zinc finger proteinprovided by HGNC
Primary source
HGNC:HGNC:23241
See related
Ensembl:ENSG00000196670 MIM:610281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZET; ZNF755
Annotation information
Note: Annotation of ZFP62 was placed on AC016572.6 on NCBI's annotation 36.3. This clone has been determined to be redundant, so the annotation was merged with the location on the assembled chromosome. [02 Mar 2009]
Expression
Ubiquitous expression in thyroid (RPKM 6.7), lymph node (RPKM 4.3) and 25 other tissues See more
Orthologs

Genomic context

See ZFP62 in Genome Data Viewer
Location:
5q35.3
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (180843580..180861276, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (180272435..180288334, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105377766 Neighboring gene long intergenic non-protein coding RNA 847 Neighboring gene hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA Neighboring gene butyrophilin like 8 Neighboring gene ribosomal protein S29 pseudogene 12 Neighboring gene TERF2 interacting protein pseudogene Neighboring gene transmembrane protein 69 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ11344, FLJ34057, FLJ34231, FLJ58781, FLJ59694, MGC176438, DKFZp667F2013

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger protein 62 homolog
Names
zfp-62

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172638.2NP_001166109.1  zinc finger protein 62 homolog isoform 2

    See identical proteins and their annotated locations for NP_001166109.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon and uses an upstream start codon, compared to variant 1. The resulting isoform (2) has a longer N-terminus, compared to isoform 1.
    Source sequence(s)
    AC022413
    Consensus CDS
    CCDS54955.1
    UniProtKB/Swiss-Prot
    Q8NB50
    Related
    ENSP00000423820.1, ENST00000502412.1
    Conserved Domains (3) summary
    COG5048
    Location:447860
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:227247
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:268292
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001377939.1NP_001364868.1  zinc finger protein 62 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022413
  3. NM_001377940.1NP_001364869.1  zinc finger protein 62 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022413
  4. NM_001377941.1NP_001364870.1  zinc finger protein 62 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022413
  5. NM_001377942.1NP_001364871.1  zinc finger protein 62 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC022413
  6. NM_001377943.1NP_001364872.1  zinc finger protein 62 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC022413
  7. NM_001377944.1NP_001364873.1  zinc finger protein 62 homolog isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC022413
  8. NM_001377945.1NP_001364874.1  zinc finger protein 62 homolog isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC022413
  9. NM_152283.5NP_689496.4  zinc finger protein 62 homolog isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript but encodes the shorter isoform (1).
    Source sequence(s)
    AC022413
    Consensus CDS
    CCDS47357.2
    UniProtKB/Swiss-Prot
    Q8NB50
    Related
    ENSP00000426193.1, ENST00000512132.5
    Conserved Domains (3) summary
    COG5048
    Location:414827
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:194214
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:235259
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    180843580..180861276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009716.2XP_016865205.1  zinc finger protein 62 homolog isoform X2

  2. XM_017009718.2XP_016865207.1  zinc finger protein 62 homolog isoform X4

  3. XM_017009719.2XP_016865208.1  zinc finger protein 62 homolog isoform X5

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