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RBFOX3 RNA binding fox-1 homolog 3 [ Homo sapiens (human) ]

Gene ID: 146713, updated on 25-Nov-2021

Summary

Official Symbol
RBFOX3provided by HGNC
Official Full Name
RNA binding fox-1 homolog 3provided by HGNC
Primary source
HGNC:HGNC:27097
See related
Ensembl:ENSG00000167281 MIM:616999
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FOX3; NEUN; FOX-3; HRNBP3
Summary
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]
Expression
Biased expression in brain (RPKM 11.3), prostate (RPKM 4.9) and 4 other tissues See more
Orthologs
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Genomic context

See RBFOX3 in Genome Data Viewer
Location:
17q25.3
Exon count:
39
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (79089345..79665600, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (77085427..77632826, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 5335 Neighboring gene endo-beta-N-acetylglucosaminidase Neighboring gene Sharpr-MPRA regulatory region 4769 Neighboring gene long intergenic non-protein coding RNA 2078 Neighboring gene microRNA 4739

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
GeneReviews: Not available

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Tat tat HIV-1 Tat downregulates the expression of RBFOX3/NEUN in human neurons PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ44838, FLJ56884, FLJ58356, MGC176616

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in RNA splicing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
RNA binding protein fox-1 homolog 3
Names
RNA binding protein, fox-1 homolog 3
fox-1 homolog C
hexaribonucleotide binding protein 3
neuN antigen
neuronal nuclei antigen

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053112.1 RefSeqGene

    Range
    100056..526859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001082575.3NP_001076044.1  RNA binding protein fox-1 homolog 3 isoform 1

    See identical proteins and their annotated locations for NP_001076044.1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Consensus CDS
    CCDS45805.1
    UniProtKB/Swiss-Prot
    A6NFN3
    Related
    ENSP00000463653.1, ENST00000580155.5
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  2. NM_001350451.2NP_001337380.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  3. NM_001350453.2NP_001337382.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Consensus CDS
    CCDS45805.1
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  4. NM_001385804.1NP_001372733.1  RNA binding protein fox-1 homolog 3 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  5. NM_001385805.1NP_001372734.1  RNA binding protein fox-1 homolog 3 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  6. NM_001385806.1NP_001372735.1  RNA binding protein fox-1 homolog 3 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (4) summary
    PRK13335
    Location:2485
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  7. NM_001385807.1NP_001372736.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  8. NM_001385808.1NP_001372737.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  9. NM_001385809.1NP_001372738.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  10. NM_001385810.1NP_001372739.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  11. NM_001385811.1NP_001372740.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  12. NM_001385812.1NP_001372741.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  13. NM_001385813.1NP_001372742.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  14. NM_001385814.1NP_001372743.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Related
    ENSP00000497797.1, ENST00000648001.1
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  15. NM_001385815.1NP_001372744.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  16. NM_001385816.1NP_001372745.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  17. NM_001385817.1NP_001372746.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  18. NM_001385818.1NP_001372747.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  19. NM_001385819.1NP_001372748.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  20. NM_001385820.1NP_001372749.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  21. NM_001385821.1NP_001372750.1  RNA binding protein fox-1 homolog 3 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  22. NM_001385822.1NP_001372751.1  RNA binding protein fox-1 homolog 3 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Related
    ENSP00000464186.1, ENST00000583458.5
    Conserved Domains (4) summary
    PRK13335
    Location:2485
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  23. NM_001385823.1NP_001372752.1  RNA binding protein fox-1 homolog 3 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (4) summary
    PRK13335
    Location:2485
    PRK13335; superantigen-like protein SSL3; Reviewed
    COG0724
    Location:71231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:207343
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  24. NM_001385824.1NP_001372753.1  RNA binding protein fox-1 homolog 3 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Related
    ENSP00000463964.1, ENST00000582043.5
    Conserved Domains (3) summary
    COG0724
    Location:27133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177313
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99138
    RRM_SF; RNA recognition motif (RRM) superfamily
  25. NM_001385825.1NP_001372754.1  RNA binding protein fox-1 homolog 3 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Related
    ENSP00000462007.1, ENST00000584778.5
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  26. NM_001385826.1NP_001372755.1  RNA binding protein fox-1 homolog 3 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  27. NM_001385827.1NP_001372756.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27239
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:215304
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  28. NM_001385828.1NP_001372757.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  29. NM_001385829.1NP_001372758.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  30. NM_001385830.1NP_001372759.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  31. NM_001385831.1NP_001372760.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  32. NM_001385832.1NP_001372761.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  33. NM_001385833.1NP_001372762.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  34. NM_001385834.1NP_001372763.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  35. NM_001385835.1NP_001372764.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  36. NM_001385836.1NP_001372765.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  37. NM_001385837.1NP_001372766.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  38. NM_001385838.1NP_001372767.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  39. NM_001385839.1NP_001372768.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  40. NM_001385840.1NP_001372769.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  41. NM_001385841.1NP_001372770.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  42. NM_001385842.1NP_001372771.1  RNA binding protein fox-1 homolog 3 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208297
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  43. NM_001385843.1NP_001372772.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    TIGR01661
    Location:25169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  44. NM_001385844.1NP_001372773.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624
    Conserved Domains (3) summary
    TIGR01661
    Location:25169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  45. NM_001385845.1NP_001372774.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    TIGR01661
    Location:25169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  46. NM_001385846.1NP_001372775.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    TIGR01661
    Location:25169
    ELAV_HUD_SF; ELAV/HuD family splicing factor
    pfam12414
    Location:207296
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:98173
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  47. NM_001385847.1NP_001372776.1  RNA binding protein fox-1 homolog 3 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC020689, AC021534, AC055858, AC073624, AC233701
    Conserved Domains (3) summary
    PRK10927
    Location:23155
    PRK10927; cell division protein FtsN
    pfam12414
    Location:159248
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99120
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    79089345..79665600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024211.2XP_016879700.1  RNA binding protein fox-1 homolog 3 isoform X11

    Conserved Domains (3) summary
    COG0724
    Location:27133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177266
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99138
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. XM_024450593.1XP_024306361.1  RNA binding protein fox-1 homolog 3 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  3. XM_024450592.1XP_024306360.1  RNA binding protein fox-1 homolog 3 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  4. XM_017024208.1XP_016879697.1  RNA binding protein fox-1 homolog 3 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  5. XM_011524366.2XP_011522668.1  RNA binding protein fox-1 homolog 3 isoform X7

    Conserved Domains (3) summary
    PRK13335
    Location:2485
    PRK13335; superantigen-like protein SSL3; Reviewed
    smart00360
    Location:99169
    RRM; RNA recognition motif
    COG0724
    Location:71231
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
  6. XM_011524367.2XP_011522669.1  RNA binding protein fox-1 homolog 3 isoform X10

    Conserved Domains (3) summary
    COG0724
    Location:27133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177266
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99138
    RRM_SF; RNA recognition motif (RRM) superfamily
  7. XM_017024209.1XP_016879698.1  RNA binding protein fox-1 homolog 3 isoform X5

    Conserved Domains (3) summary
    COG0724
    Location:27133
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:177313
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cl17169
    Location:99138
    RRM_SF; RNA recognition motif (RRM) superfamily
  8. XM_011524360.1XP_011522662.1  RNA binding protein fox-1 homolog 3 isoform X1

    See identical proteins and their annotated locations for XP_011522662.1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  9. XM_024450596.1XP_024306364.1  RNA binding protein fox-1 homolog 3 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
  10. XM_024450595.1XP_024306363.1  RNA binding protein fox-1 homolog 3 isoform X1

    Conserved Domains (3) summary
    COG0724
    Location:27232
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    pfam12414
    Location:208344
    Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    cd12407
    Location:99174
    RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001025448.1: Suppressed sequence

    Description
    NM_001025448.1: This RefSeq was permanently suppressed because it contains the wrong CDS.
  2. NM_001039904.1: Suppressed sequence

    Description
    NM_001039904.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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