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Ptk2 PTK2 protein tyrosine kinase 2 [ Mus musculus (house mouse) ]

Gene ID: 14083, updated on 19-Feb-2024

Summary

Official Symbol
Ptk2provided by MGI
Official Full Name
PTK2 protein tyrosine kinase 2provided by MGI
Primary source
MGI:MGI:95481
See related
Ensembl:ENSMUSG00000022607 AllianceGenome:MGI:95481
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FAK; FRNK; Fadk; FADK 1; p125FAK
Summary
Enables non-membrane spanning protein tyrosine kinase activity. Involved in positive regulation of cell population proliferation; positive regulation of ubiquitin-dependent protein catabolic process; and protein phosphorylation. Acts upstream of or within several processes, including blood vessel morphogenesis; generation of neurons; and peptidyl-tyrosine autophosphorylation. Located in several cellular components, including apical plasma membrane; focal adhesion; and lamellipodium. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and yolk sac. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cortex adult (RPKM 12.3), CNS E11.5 (RPKM 11.8) and 28 other tissues See more
Orthologs
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Genomic context

See Ptk2 in Genome Data Viewer
Location:
15 D3; 15 33.94 cM
Exon count:
42
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (73076951..73297192, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (73205102..73423820, complement)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_38946 Neighboring gene chromatin accessibility complex 1 Neighboring gene predicted gene, 31725 Neighboring gene STARR-positive B cell enhancer ABC_E8595 Neighboring gene argonaute RISC catalytic subunit 2 Neighboring gene STARR-positive B cell enhancer ABC_E7379 Neighboring gene STARR-positive B cell enhancer ABC_E10861 Neighboring gene STARR-positive B cell enhancer ABC_E7380 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:73017364-73017547 Neighboring gene STARR-seq mESC enhancer starr_38954 Neighboring gene STARR-seq mESC enhancer starr_38957 Neighboring gene microRNA 151 Neighboring gene predicted gene, 41344 Neighboring gene predicted gene, 24787 Neighboring gene STARR-seq mESC enhancer starr_38959 Neighboring gene STARR-positive B cell enhancer mm9_chr15:73254258-73254558 Neighboring gene protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b pseudogene Neighboring gene STARR-seq mESC enhancer starr_38960 Neighboring gene ribosomal protein L17 pseudogene Neighboring gene STARR-seq mESC enhancer starr_38961 Neighboring gene STARR-positive B cell enhancer ABC_E7381 Neighboring gene cytochrome b-c1 complex subunit 6, mitochondrial pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (17)  1 citation
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA4203

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables JUN kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables SH2 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables actin binding ISO
Inferred from Sequence Orthology
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular function activator activity ISO
Inferred from Sequence Orthology
more info
 
enables non-membrane spanning protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables non-membrane spanning protein tyrosine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables non-membrane spanning protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables phosphatidylinositol 3-kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein tyrosine kinase activity EXP
Inferred from Experiment
more info
PubMed 
enables protein tyrosine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein tyrosine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein tyrosine kinase activity TAS
Traceable Author Statement
more info
 
enables protein tyrosine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in JNK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within blood vessel development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cell migration TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within cellular response to transforming growth factor beta stimulus IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within central nervous system neuron axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within endothelial cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ephrin receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within extracellular matrix organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in growth hormone receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within integrin-mediated signaling pathway TAS
Traceable Author Statement
more info
PubMed 
involved_in intracellular chloride ion homeostasis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within microtubule cytoskeleton organization IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of anoikis ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of autophagy IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of autophagy IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of organ growth IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within negative regulation of synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuron migration IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within neuron migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within nuclear migration IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of organ growth IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within peptidyl-tyrosine autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of cardiac muscle hypertrophy IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell growth ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of epithelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of fibroblast migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of positive regulation of macrophage chemotaxis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of positive regulation of macrophage proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phagocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of smooth muscle cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of smooth muscle cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of wound healing ISO
Inferred from Sequence Orthology
more info
 
involved_in protein autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within protein autophosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein autophosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cell adhesion mediated by integrin ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of epithelial cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of modification of postsynaptic actin cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of modification of postsynaptic actin cytoskeleton IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of osteoblast differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of substrate adhesion-dependent cell spreading ISO
Inferred from Sequence Orthology
more info
 
involved_in signal complex assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within vasculogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vasodilation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
 
located_in apical plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in ciliary basal body ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
is_active_in dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in intercalated disc ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynapse ISO
Inferred from Sequence Orthology
more info
 
located_in sarcolemma ISO
Inferred from Sequence Orthology
more info
 
located_in stress fiber ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
focal adhesion kinase 1
Names
focal adhesion kinase-related nonkinase
focal ashension kinase 1
pp125FAK
protein-tyrosine kinase 2
NP_001344974.1
NP_001344975.1
NP_032008.2
XP_006520478.1
XP_006520479.1
XP_006520487.1
XP_006520488.1
XP_006520490.1
XP_006520491.1
XP_006520492.1
XP_006520493.1
XP_006520494.1
XP_006520495.1
XP_006520497.1
XP_006520498.1
XP_030104179.1
XP_030104180.1
XP_030104184.1
XP_030104186.1
XP_030104188.1
XP_030104190.1
XP_030104191.1
XP_030104192.1
XP_036015019.1
XP_036015020.1
XP_036015021.1
XP_036015022.1
XP_036015023.1
XP_036015024.1
XP_036015027.1
XP_036015028.1
XP_036015029.1
XP_036015030.1
XP_036015031.1
XP_036015032.1
XP_036015033.1
XP_036015035.1
XP_036015036.1
XP_036015037.1
XP_036015038.1
XP_036015039.1
XP_036015040.1
XP_036015041.1
XP_036015042.1
XP_036015044.1
XP_036015045.1
XP_036015046.1
XP_036015047.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358045.1NP_001344974.1  focal adhesion kinase 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains alternate exons in the 5' UTR and 3' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AC121319, AC132863, AC161581
    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:459728
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9631092
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  2. NM_001358046.1NP_001344975.1  focal adhesion kinase 1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 4, which is longer than isoform 1.
    Source sequence(s)
    AC121319, AC132863, AC161581
    UniProtKB/TrEMBL
    A0A5F8MPY3, K7Q751
    Conserved Domains (5) summary
    cd05056
    Location:428697
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9321061
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  3. NM_007982.2NP_032008.2  focal adhesion kinase 1 isoform 1

    See identical proteins and their annotated locations for NP_032008.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AK220543, BB816209
    Consensus CDS
    CCDS37099.1
    UniProtKB/Swiss-Prot
    O08578, P34152, Q5DTH7, Q8C513, Q8CFH7, Q8CHM2, Q8K2S0, Q9DAW3
    UniProtKB/TrEMBL
    A0A5F8MPY3
    Related
    ENSMUSP00000105663.3, ENSMUST00000110036.11
    Conserved Domains (4) summary
    cd05056
    Location:415684
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9161045
    Focal_AT; Focal adhesion targeting region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    73076951..73297192 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036159142.1XP_036015035.1  focal adhesion kinase 1 isoform X14

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  2. XM_036159153.1XP_036015046.1  focal adhesion kinase 1 isoform X23

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:314583
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:16157
    B41; Band 4.1 homologues
    cd13190
    Location:153263
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:818947
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:129
    FERM_N_2; FERM N-terminal domain
  3. XM_036159152.1XP_036015045.1  focal adhesion kinase 1 isoform X22

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:327596
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:16157
    B41; Band 4.1 homologues
    cd13190
    Location:153263
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:831960
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:129
    FERM_N_2; FERM N-terminal domain
  4. XM_006520434.4XP_006520497.1  focal adhesion kinase 1 isoform X21

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:355624
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:16157
    B41; Band 4.1 homologues
    cd13190
    Location:153263
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:859988
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:129
    FERM_N_2; FERM N-terminal domain
  5. XM_030248332.2XP_030104192.1  focal adhesion kinase 1 isoform X20

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:415684
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9191048
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  6. XM_036159146.1XP_036015039.1  focal adhesion kinase 1 isoform X19

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9261055
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  7. XM_006520424.4XP_006520487.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520487.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  8. XM_006520416.4XP_006520479.1  focal adhesion kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_006520479.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  9. XM_036159149.1XP_036015042.1  focal adhesion kinase 1 isoform X20

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:415684
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9191048
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  10. XM_036159147.1XP_036015040.1  focal adhesion kinase 1 isoform X19

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9261055
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  11. XM_036159145.1XP_036015038.1  focal adhesion kinase 1 isoform X18

    UniProtKB/TrEMBL
    A0A5F8MPY3, K7Q751
    Conserved Domains (5) summary
    cd05056
    Location:428697
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9321061
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  12. XM_006520425.4XP_006520488.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520488.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  13. XM_006520415.4XP_006520478.1  focal adhesion kinase 1 isoform X1

    See identical proteins and their annotated locations for XP_006520478.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  14. XM_006520429.4XP_006520492.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520492.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  15. XM_030248320.2XP_030104180.1  focal adhesion kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  16. XM_006520428.4XP_006520491.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520491.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  17. XM_006520427.5XP_006520490.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520490.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  18. XM_030248319.2XP_030104179.1  focal adhesion kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  19. XM_036159140.1XP_036015033.1  focal adhesion kinase 1 isoform X14

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  20. XM_030248330.2XP_030104190.1  focal adhesion kinase 1 isoform X17

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:459728
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9421071
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  21. XM_006520432.4XP_006520495.1  focal adhesion kinase 1 isoform X15

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:459728
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  22. XM_036159139.1XP_036015032.1  focal adhesion kinase 1 isoform X13

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:459728
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9631092
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  23. XM_036159138.1XP_036015031.1  focal adhesion kinase 1 isoform X11

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:466735
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9671096
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  24. XM_036159136.1XP_036015029.1  focal adhesion kinase 1 isoform X9

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:466735
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9701099
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  25. XM_030248326.2XP_030104186.1  focal adhesion kinase 1 isoform X12

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:465734
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9661095
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  26. XM_036159137.1XP_036015030.1  focal adhesion kinase 1 isoform X10

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:465734
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9691098
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  27. XM_036159144.1XP_036015037.1  focal adhesion kinase 1 isoform X16

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:472741
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9551084
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  28. XM_036159135.1XP_036015028.1  focal adhesion kinase 1 isoform X7

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:472741
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9761105
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  29. XM_030248324.2XP_030104184.1  focal adhesion kinase 1 isoform X8

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:493762
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9731102
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  30. XM_036159130.1XP_036015023.1  focal adhesion kinase 1 isoform X4

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:493762
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9941123
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  31. XM_036159129.1XP_036015022.1  focal adhesion kinase 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:493762
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9971126
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  32. XM_036159134.1XP_036015027.1  focal adhesion kinase 1 isoform X6

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9801109
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  33. XM_036159131.1XP_036015024.1  focal adhesion kinase 1 isoform X5

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9831112
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  34. XM_036159128.1XP_036015021.1  focal adhesion kinase 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10011130
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  35. XM_036159126.1XP_036015019.1  focal adhesion kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  36. XM_030248328.2XP_030104188.1  focal adhesion kinase 1 isoform X14

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  37. XM_036159127.1XP_036015020.1  focal adhesion kinase 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:500769
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:80302
    B41; Band 4.1 homologues
    cd13190
    Location:298408
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:10041133
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:79174
    FERM_N_2; FERM N-terminal domain
  38. XM_006520430.2XP_006520493.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520493.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  39. XM_006520431.2XP_006520494.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520494.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  40. XM_036159151.1XP_036015044.1  focal adhesion kinase 1 isoform X21

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:355624
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:16157
    B41; Band 4.1 homologues
    cd13190
    Location:153263
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:859988
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:129
    FERM_N_2; FERM N-terminal domain
  41. XM_006520435.5XP_006520498.1  focal adhesion kinase 1 isoform X14

    See identical proteins and their annotated locations for XP_006520498.1

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Related
    ENSMUSP00000159174.2, ENSMUST00000239146.2
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  42. XM_036159148.1XP_036015041.1  focal adhesion kinase 1 isoform X19

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:422691
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9261055
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  43. XM_030248331.1XP_030104191.1  focal adhesion kinase 1 isoform X20

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Related
    ENSMUSP00000154242.2, ENSMUST00000226988.3
    Conserved Domains (5) summary
    cd05056
    Location:415684
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9191048
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  44. XM_036159143.1XP_036015036.1  focal adhesion kinase 1 isoform X14

    UniProtKB/TrEMBL
    A0A5F8MPY3
    Conserved Domains (5) summary
    cd05056
    Location:456725
    PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
    smart00295
    Location:36258
    B41; Band 4.1 homologues
    cd13190
    Location:254364
    FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    pfam03623
    Location:9601089
    Focal_AT; Focal adhesion targeting region
    pfam18038
    Location:35130
    FERM_N_2; FERM N-terminal domain
  45. XM_036159154.1XP_036015047.1  focal adhesion kinase 1 isoform X24

    Conserved Domains (1) summary
    pfam03623
    Location:229358
    Focal_AT; Focal adhesion targeting region

RNA

  1. XR_004938793.1 RNA Sequence

  2. XR_003951347.2 RNA Sequence

  3. XR_004938792.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001130409.1: Suppressed sequence

    Description
    NM_001130409.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.