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Birc6 baculoviral IAP repeat-containing 6 [ Mus musculus (house mouse) ]

Gene ID: 12211, updated on 8-Jan-2023

Summary

Official Symbol
Birc6provided by MGI
Official Full Name
baculoviral IAP repeat-containing 6provided by MGI
Primary source
MGI:MGI:1276108
See related
Ensembl:ENSMUSG00000024073 AllianceGenome:MGI:1276108
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Bruce; mKIAA1289; A430032G04Rik; A430040A19Rik; D630005A10Rik
Summary
Enables ubiquitin conjugating enzyme activity. Involved in placenta development. Acts upstream of or within embryonic placenta development; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Located in membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human BIRC6 (baculoviral IAP repeat containing 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 13.8), spleen adult (RPKM 8.0) and 28 other tissues See more
Orthologs
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Genomic context

See Birc6 in Genome Data Viewer
Location:
17; 17 E2
Exon count:
75
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (74835247..75010351)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (74528254..74703356)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene Yip1 domain family, member 4 Neighboring gene predicted gene, 31645 Neighboring gene tetratricopeptide repeat domain 27 Neighboring gene predicted gene, 31759

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (3)  1 citation
  • Targeted (2)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cysteine-type endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin conjugating enzyme activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within labyrinthine layer development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of extrinsic apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in placenta development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein ubiquitination IC
Inferred by Curator
more info
PubMed 
acts_upstream_of_or_within regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cytokinesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within spongiotrophoblast layer development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
located_in midbody ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle pole ISO
Inferred from Sequence Orthology
more info
 
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
baculoviral IAP repeat-containing protein 6
Names
BIR repeat-containing ubiquitin-conjugating enzyme
RING-type E3 ubiquitin transferase BIRC6
apollon
baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme
baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme; accccbaculoviral IAP repeat-containing 6
ubiquitin-conjugating BIR domain enzyme apollon
NP_031592.3
XP_006523581.1
XP_006523582.1
XP_006523583.1
XP_006523584.1
XP_006523585.1
XP_006523586.1
XP_006523587.1
XP_006523589.1
XP_006523590.1
XP_006523591.1
XP_011244559.1
XP_030105313.1
XP_030105314.1
XP_030105315.1
XP_030105316.1
XP_030105317.1
XP_030105318.1
XP_036016165.1
XP_036016166.1
XP_036016167.1
XP_036016168.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001402769.1NP_001389698.1  baculoviral IAP repeat-containing protein 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC098726, AC154442
    UniProtKB/Swiss-Prot
    Q8C737
    UniProtKB/TrEMBL
    A0A1S6GWH3
  2. NM_007566.3NP_031592.3  baculoviral IAP repeat-containing protein 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC098726, AC154442, AK041241, AK042247, AK045446, AK052612, AK134254, AK173143, BG695066, CN536181, CN707067, CO424370, DV651019
    Consensus CDS
    CCDS37693.2
    UniProtKB/Swiss-Prot
    O88738
    UniProtKB/TrEMBL
    Q3UYZ6
    Related
    ENSMUSP00000136329.2, ENSMUST00000180037.8
    Conserved Domains (3) summary
    cd00022
    Location:290363
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46134751
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:34803632
    DUF3643; Protein of unknown function (DUF3643)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    74835247..75010351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523518.3XP_006523581.1  baculoviral IAP repeat-containing protein 6 isoform X1

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46934831
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35583712
    BIRC6; Baculoviral IAP repeat-containing protein 6
  2. XM_006523520.4XP_006523583.1  baculoviral IAP repeat-containing protein 6 isoform X3

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46874825
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35523706
    BIRC6; Baculoviral IAP repeat-containing protein 6
  3. XM_006523522.4XP_006523585.1  baculoviral IAP repeat-containing protein 6 isoform X5

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46844822
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35493703
    BIRC6; Baculoviral IAP repeat-containing protein 6
  4. XM_006523524.4XP_006523587.1  baculoviral IAP repeat-containing protein 6 isoform X9

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46784816
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35433697
    BIRC6; Baculoviral IAP repeat-containing protein 6
  5. XM_006523521.4XP_006523584.1  baculoviral IAP repeat-containing protein 6 isoform X4

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46874825
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35523706
    BIRC6; Baculoviral IAP repeat-containing protein 6
  6. XM_030249454.2XP_030105314.1  baculoviral IAP repeat-containing protein 6 isoform X10

    Related
    ENSMUSP00000138270.2, ENSMUST00000183224.8
    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46784816
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35433697
    BIRC6; Baculoviral IAP repeat-containing protein 6
  7. XM_006523527.4XP_006523590.1  baculoviral IAP repeat-containing protein 6 isoform X14

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46604798
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35253679
    BIRC6; Baculoviral IAP repeat-containing protein 6
  8. XM_006523519.4XP_006523582.1  baculoviral IAP repeat-containing protein 6 isoform X2

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46894827
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35543708
    BIRC6; Baculoviral IAP repeat-containing protein 6
  9. XM_036160272.1XP_036016165.1  baculoviral IAP repeat-containing protein 6 isoform X6

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46834821
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35483702
    BIRC6; Baculoviral IAP repeat-containing protein 6
  10. XM_030249453.2XP_030105313.1  baculoviral IAP repeat-containing protein 6 isoform X7

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46804818
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35453699
    BIRC6; Baculoviral IAP repeat-containing protein 6
  11. XM_030249456.2XP_030105316.1  baculoviral IAP repeat-containing protein 6 isoform X16

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46564794
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35213675
    BIRC6; Baculoviral IAP repeat-containing protein 6
  12. XM_006523523.5XP_006523586.1  baculoviral IAP repeat-containing protein 6 isoform X8

    UniProtKB/TrEMBL
    A0A1S6GWH6
    Related
    ENSMUSP00000138333.2, ENSMUST00000182597.8
    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46794817
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35443698
    BIRC6; Baculoviral IAP repeat-containing protein 6
  13. XM_036160273.1XP_036016166.1  baculoviral IAP repeat-containing protein 6 isoform X12

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46734811
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35383692
    BIRC6; Baculoviral IAP repeat-containing protein 6
  14. XM_030249457.2XP_030105317.1  baculoviral IAP repeat-containing protein 6 isoform X18

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46464784
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35113665
    BIRC6; Baculoviral IAP repeat-containing protein 6
  15. XM_030249455.2XP_030105315.1  baculoviral IAP repeat-containing protein 6 isoform X11

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46754813
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35403694
    BIRC6; Baculoviral IAP repeat-containing protein 6
  16. XM_006523526.5XP_006523589.1  baculoviral IAP repeat-containing protein 6 isoform X13

    Related
    ENSMUSP00000138732.2, ENSMUST00000182944.8
    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46664804
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35313685
    BIRC6; Baculoviral IAP repeat-containing protein 6
  17. XM_036160274.1XP_036016167.1  baculoviral IAP repeat-containing protein 6 isoform X15

    Related
    ENSMUSP00000138693.2, ENSMUST00000182133.8
    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46604798
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35253679
    BIRC6; Baculoviral IAP repeat-containing protein 6
  18. XM_030249458.2XP_030105318.1  baculoviral IAP repeat-containing protein 6 isoform X19

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46424780
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35073661
    BIRC6; Baculoviral IAP repeat-containing protein 6
  19. XM_006523528.5XP_006523591.1  baculoviral IAP repeat-containing protein 6 isoform X17

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46494787
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:35143668
    BIRC6; Baculoviral IAP repeat-containing protein 6
  20. XM_036160275.1XP_036016168.1  baculoviral IAP repeat-containing protein 6 isoform X20

    Conserved Domains (3) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:46304768
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:34953649
    BIRC6; Baculoviral IAP repeat-containing protein 6
  21. XM_011246257.4XP_011244559.1  baculoviral IAP repeat-containing protein 6 isoform X21

    Conserved Domains (2) summary
    cd00022
    Location:347420
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    pfam12356
    Location:35583712
    BIRC6; Baculoviral IAP repeat-containing protein 6

RNA

  1. XR_004939463.1 RNA Sequence

  2. XR_003952080.2 RNA Sequence

  3. XR_003952078.2 RNA Sequence

  4. XR_385268.5 RNA Sequence