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Ago2 argonaute RISC catalytic component 2 [ Peromyscus maniculatus bairdii (prairie deer mouse) ]

Gene ID: 102925621, updated on 10-Mar-2024

Summary

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Gene symbol
Ago2
Gene description
argonaute RISC catalytic component 2
See related
Ensembl:ENSPEMG00000008137
Gene type
protein coding
RefSeq status
MODEL
Organism
Peromyscus maniculatus bairdii (sub-species: bairdii)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Neotominae; Peromyscus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
20
Annotation release Status Assembly Chr Location
102 current HU_Pman_2.1.3 (GCF_003704035.1) 20 NC_056027.1 (39269749..39360231, complement)
101 previous assembly Pman_1.0 (GCF_000500345.1) Unplaced Scaffold NW_006501447.1 (1241890..1332321, complement)

Chromosome 20 - NC_056027.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 9 Neighboring gene uncharacterized LOC121824515 Neighboring gene chromatin accessibility complex subunit 1 Neighboring gene protein tyrosine kinase 2 Neighboring gene uncharacterized LOC121824493

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endoribonuclease activity, cleaving siRNA-paired mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulatory ncRNA-mediated gene silencing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of RISC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein argonaute-2
Names
argonaute 2, RISC catalytic component

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Peromyscus maniculatus bairdii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HU_Pman_2.1.3 Primary Assembly

Genomic

  1. NC_056027.1 Reference HU_Pman_2.1.3 Primary Assembly

    Range
    39269749..39360231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006989198.3 → XP_006989260.2  protein argonaute-2 isoform X1

    UniProtKB/TrEMBL
    A0A6I9M856, A0A6J0E9K0
    Conserved Domains (5) summary
    PLN03202
    Location:7 → 868
    PLN03202; protein argonaute; Provisional
    cd02846
    Location:228 → 348
    PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
    cd04657
    Location:393 → 827
    Piwi_ago-like; Piwi_ago-like: PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of ...
    pfam08699
    Location:178 → 227
    ArgoL1; Argonaute linker 1 domain
    pfam16486
    Location:29 → 167
    ArgoN; N-terminal domain of argonaute

  2. XM_042264972.1 → XP_042120906.1  protein argonaute-2 isoform X2

    UniProtKB/TrEMBL
    A0A6J0E9K0, A0A8C8T7Q2
    Conserved Domains (2) summary
    PLN03202
    Location:7 → 859
    PLN03202; protein argonaute; Provisional
    cd04657
    Location:393 → 818
    Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
Nucleotide Protein
Heading Accession and Version

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