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Limch1 LIM and calponin homology domains 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101699932, updated on 8-Mar-2024

Summary

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Gene symbol
Limch1
Gene description
LIM and calponin homology domains 1
Locus tag
GW7_07523
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624761.1 (25375501..25706756, complement)

NW_004624761.1Genomic Context describing neighboring genes Neighboring gene protein CDV3 homolog pseudogene Neighboring gene paired like homeobox 2B Neighboring gene dynactin subunit 6 pseudogene Neighboring gene ubiquitin C-terminal hydrolase L1 Neighboring gene amyloid beta precursor protein binding family B member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624761 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables myosin II head/neck binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of stress fiber assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of focal adhesion assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM and calponin homology domains-containing protein 1
Names
LIM and calponin-like protein domains-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624761.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    25375501..25706756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021262418.1 → XP_021118077.1  LIM and calponin homology domains-containing protein 1

    UniProtKB/TrEMBL
    G5ANE6
    Conserved Domains (4) summary
    smart00132
    Location:1499 → 1556
    LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3
    cd00014
    Location:26 → 138
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam05505
    Location:885 → 1285
    Ebola_NP; Ebola nucleoprotein
    pfam15949
    Location:749 → 875
    DUF4757; Domain of unknown function (DUF4757)
Nucleotide Protein
Heading Accession and Version

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