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Dhx8 DEAH-box helicase 8 [ Octodon degus (degu) ]

Gene ID: 101588885, updated on 8-Mar-2024

Summary

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Gene symbol
Dhx8
Gene description
DEAH-box helicase 8
See related
Ensembl:ENSODEG00000018025
Gene type
protein coding
RefSeq status
MODEL
Organism
Octodon degus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Octodontidae; Octodon
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
102 current OctDeg1.0 (GCF_000260255.1) Unplaced Scaffold NW_004524632.1 (11519290..11541429)

NW_004524632.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111817354 Neighboring gene ADP ribosylation factor like GTPase 4D Neighboring gene ETS variant transcription factor 4 Neighboring gene mesenchyme homeobox 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004524632 Unplaced Scaffold Reference OctDeg1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in spliceosomal complex disassembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent RNA helicase DHX8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Octodon degus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OctDeg1.0 Primary Assembly

Genomic

  1. NW_004524632.1 Reference OctDeg1.0 Primary Assembly

    Range
    11519290..11541429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004633806.2 → XP_004633863.1  ATP-dependent RNA helicase DHX8

    UniProtKB/TrEMBL
    A0A6P3EXB6
    Related
    ENSODEP00000024623.1, ENSODET00000024900.1
    Conserved Domains (6) summary
    smart00487
    Location:554 → 739
    DEXDc; DEAD-like helicases superfamily
    smart00847
    Location:957 → 1039
    HA2; Helicase associated domain (HA2) Add an annotation
    cd00046
    Location:575 → 713
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:738 → 895
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd05684
    Location:258 → 336
    S1_DHX8_helicase; S1_DHX8_helicase: The N-terminal S1 domain of human ATP-dependent RNA helicase DHX8, a DEAH (Asp-Glu-Ala-His) box polypeptide. The DEAH-box RNA helicases are thought to play key roles in pre-mRNA splicing and DHX8 facilitates nuclear export of spliced ...
    pfam07717
    Location:1073 → 1172
    OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
Nucleotide Protein
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