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Zfp282 zinc finger protein 282 [ Mus musculus (house mouse) ]

Gene ID: 101095, updated on 5-Mar-2024

Summary

Official Symbol
Zfp282provided by MGI
Official Full Name
zinc finger protein 282provided by MGI
Primary source
MGI:MGI:2141413
See related
Ensembl:ENSMUSG00000025821 AllianceGenome:MGI:2141413
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HUB1; E430019K09Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in 1st branchial arch maxillary component; early conceptus; genitourinary system; and limb. Orthologous to human ZNF282 (zinc finger protein 282). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 8.4), CNS E18 (RPKM 7.7) and 28 other tissues See more
Orthologs
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Genomic context

Location:
6 B2.3; 6 22.94 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (47853433..47885419)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (47877209..47908485)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L35A, pseudogene 7 Neighboring gene STARR-seq mESC enhancer starr_15785 Neighboring gene zinc finger protein 786 Neighboring gene zinc finger protein 398 Neighboring gene predicted gene, 52899 Neighboring gene Zinc finger protein 212 Neighboring gene STARR-positive B cell enhancer ABC_E8099 Neighboring gene zinc finger protein 783 Neighboring gene zinc finger protein 956

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146175.3NP_666287.3  zinc finger protein 282

    Status: VALIDATED

    Source sequence(s)
    AC166248, AK030516, AK030919, AK148038, BX524317, BY129988
    Consensus CDS
    CCDS20100.1
    UniProtKB/TrEMBL
    E9PVC2, Q8R3D4
    Related
    ENSMUSP00000053643.7, ENSMUST00000061890.8
    Conserved Domains (6) summary
    smart00349
    Location:198260
    KRAB; krueppel associated box
    COG5048
    Location:568621
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:544564
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:570592
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:198237
    KRAB; KRAB box
    pfam13465
    Location:612637
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    47853433..47885419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241099.4XP_011239401.1  zinc finger protein 282 isoform X1

    UniProtKB/TrEMBL
    Q8R3D4
    Conserved Domains (5) summary
    smart00349
    Location:198260
    KRAB; krueppel associated box
    sd00017
    Location:516536
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:514536
    zf-C2H2; Zinc finger, C2H2 type
    pfam12417
    Location:112168
    DUF3669; Zinc finger protein
    pfam13465
    Location:528553
    zf-H2C2_2; Zinc-finger double domain