U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CHUK component of inhibitor of nuclear factor kappa B kinase complex [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100995228, updated on 6-Jun-2024

Summary

Go to the top of the page Help
Gene symbol
CHUK
Gene description
component of inhibitor of nuclear factor kappa B kinase complex
See related
Ensembl:ENSPPAG00000037851
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 8
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 8 NC_073257.2 (112077682..112118610, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 10 NC_073259.1 (112083001..112123929, complement)

Chromosome 8 - NC_073257.2Genomic Context describing neighboring genes Neighboring gene signal peptidase complex subunit 2-like Neighboring gene ER lipid raft associated 1 Neighboring gene small nucleolar RNA SNORA12 Neighboring gene CWF19 like cell cycle control factor 1 Neighboring gene prohibitin 1-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables IkappaB kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of IkappaB kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
inhibitor of nuclear factor kappa-B kinase subunit alpha
Names
conserved helix-loop-helix ubiquitous kinase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073257.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    112077682..112118610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008950784.3 → XP_008949032.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3

    UniProtKB/TrEMBL
    A0A2R9BT18
    Related
    ENSPPAP00000029716.1
    Conserved Domains (2) summary
    smart00220
    Location:15 → 298
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14039
    Location:21 → 309
    STKc_IKK_alpha; Catalytic domain of the Serine/Threonine kinase, Inhibitor of Nuclear Factor-KappaB Kinase (IKK) alpha

  2. XM_003825463.5 → XP_003825511.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A2R9BT18
    Conserved Domains (4) summary
    cd14039
    Location:21 → 309
    STKc_IKK_alpha; Catalytic domain of the Serine/Threonine kinase, Inhibitor of Nuclear Factor-KappaB Kinase (IKK) alpha
    cd17046
    Location:311 → 387
    Ubl_IKKA_like; ubiquitin-like (Ubl) domain found in inhibitor of nuclear factor kappa-B kinases, IKK-alpha and IKK-beta, and similar proteins
    pfam12179
    Location:709 → 743
    IKKbetaNEMObind; I-kappa-kinase-beta NEMO binding domain
    pfam18397
    Location:386 → 659
    IKBKB_SDD; IQBAL scaffold dimerization domain

  3. XM_055093277.1 → XP_054949252.1  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A2R9BMS4
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.