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Mars1 methionyl-tRNA synthetase 1 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100756755, updated on 8-Mar-2024

Summary

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Gene symbol
Mars1
Gene description
methionyl-tRNA synthetase 1
See related
Ensembl:ENSCGRG00015028400
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
Mars
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614393.1 (453260..467895)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (130417049..130431884)

NW_003614393.1Genomic Context describing neighboring genes Neighboring gene GLI family zinc finger 1 Neighboring gene Rho GTPase activating protein 9 Neighboring gene DNA damage inducible transcript 3 Neighboring gene methyl-CpG binding domain protein 6 Neighboring gene dynactin subunit 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methionine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in methionyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of aminoacyl-tRNA synthetase multienzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methionine--tRNA ligase, cytoplasmic
Names
Methionyl-tRNA synthetase, cytoplasmic
methionyl-tRNA synthetase, cytoplasmic-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614393.1 Reference CriGri_1.0 Primary Assembly

    Range
    453260..467895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003507499.5 → XP_003507547.1  methionine--tRNA ligase, cytoplasmic isoform X1

    See identical proteins and their annotated locations for XP_003507547.1

    UniProtKB/TrEMBL
    G3HW44
    Conserved Domains (7) summary
    cd07957
    Location:642 → 771
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:265 → 633
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    COG0625
    Location:47 → 189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    PRK12268
    Location:264 → 819
    PRK12268; methionyl-tRNA synthetase; Reviewed
    cd00939
    Location:853 → 897
    MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
    cl00388
    Location:1 → 68
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

  2. XM_035459213.1 → XP_035315104.1  methionine--tRNA ligase, cytoplasmic isoform X3

    UniProtKB/TrEMBL
    A0A9J7H8F1
    Conserved Domains (3) summary
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    PLN02610
    Location:256 → 729
    PLN02610; probable methionyl-tRNA synthetase
    pfam18485
    Location:1 → 74
    GST_N_5; Glutathione S-transferase, N-terminal domain

  3. XM_003507498.5 → XP_003507546.1  methionine--tRNA ligase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A8C2MK59
    Conserved Domains (7) summary
    cd07957
    Location:642 → 771
    Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
    cd00814
    Location:265 → 633
    MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    COG0625
    Location:47 → 189
    GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
    PRK12268
    Location:264 → 819
    PRK12268; methionyl-tRNA synthetase; Reviewed
    cd00939
    Location:845 → 889
    MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
    cl00388
    Location:1 → 68
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

RNA

  1. XR_004774493.1 RNA Sequence

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    130417049..130431884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027392224.2 → XP_027248025.1  methionine--tRNA ligase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A061ILQ3
    Related
    ENSCGRP00015037974.1, ENSCGRT00015046261.2

  2. XM_035451078.1 → XP_035306969.1  methionine--tRNA ligase, cytoplasmic isoform X3

    UniProtKB/TrEMBL
    A0A9J7H8F1
    Conserved Domains (3) summary
    cd10307
    Location:77 → 179
    GST_C_MetRS_N; Glutathione S-transferase C-terminal-like, alpha helical domain of Methionyl-tRNA synthetase from higher eukaryotes
    PLN02610
    Location:256 → 729
    PLN02610; probable methionyl-tRNA synthetase
    pfam18485
    Location:1 → 74
    GST_N_5; Glutathione S-transferase, N-terminal domain

  3. XM_027392225.2 → XP_027248026.1  methionine--tRNA ligase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A9J7F5X6
    Related
    ENSCGRP00015037975.1, ENSCGRT00015046262.2

RNA

  1. XR_004771822.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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