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SLC2A3 solute carrier family 2 member 3 [ Homo sapiens (human) ]

Gene ID: 6515, updated on 12-May-2016
Official Symbol
SLC2A3provided by HGNC
Official Full Name
solute carrier family 2 member 3provided by HGNC
Primary source
HGNC:HGNC:11007
See related
Ensembl:ENSG00000059804 HPRD:00686; MIM:138170; Vega:OTTHUMG00000133685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLUT3
Orthologs
Location:
12p13.3
Exon count:
10
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (7919228..7936296, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (8071824..8088895, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 14 Neighboring gene myosin light chain 9 pseudogene Neighboring gene Nanog homeobox pseudogene 1 Neighboring gene ribosomal protein S20 pseudogene 28 Neighboring gene heat shock protein family D (Hsp60) member 1 pseudogene Neighboring gene heat shock protein family D (Hsp60) member 1 pseudogene 12

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Replication interactions

Interaction Pubs
Knockdown of solute carrier family 2 (facilitated glucose transporter), member 3 (SLC2A3) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ90380

Gene Ontology Provided by GOA

Process Evidence Code Pubs
L-ascorbic acid metabolic process TAS
Traceable Author Statement
more info
 
carbohydrate metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
dehydroascorbic acid transport IEA
Inferred from Electronic Annotation
more info
 
glucose transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
glucose transport TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
Preferred Names
solute carrier family 2, facilitated glucose transporter member 3
Names
GLUT-3
glucose transporter type 3, brain
solute carrier family 2 (facilitated glucose transporter), member 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006931.2NP_008862.1  solute carrier family 2, facilitated glucose transporter member 3

    See identical proteins and their annotated locations for NP_008862.1

    Status: VALIDATED

    Source sequence(s)
    AC007536
    Consensus CDS
    CCDS8586.1
    UniProtKB/Swiss-Prot
    P11169
    Related
    ENSP00000075120, OTTHUMP00000165065, ENST00000075120, OTTHUMT00000257914
    Conserved Domains (2) summary
    cd06174
    Location:60448
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:15465
    Sugar_tr; Sugar (and other) transporter

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    7919228..7936296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    8070777..8087842 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)