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Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 [ Mus musculus (house mouse) ]

Gene ID: 20527, updated on 2-Aug-2020

Summary

Official Symbol
Slc2a3provided by MGI
Official Full Name
solute carrier family 2 (facilitated glucose transporter), member 3provided by MGI
Primary source
MGI:MGI:95757
See related
Ensembl:ENSMUSG00000003153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Glut3; C78366; Glut-3; AA408729; AL023014; AL024341; AU040424
Expression
Biased expression in testis adult (RPKM 213.3), placenta adult (RPKM 31.0) and 5 other tissues See more

Genomic context

See Slc2a3 in Genome Data Viewer
Location:
6 F1; 6 57.82 cM
Exon count:
12
Annotation release Status Assembly Chr Location
108.20200622 current GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (122727809..122802363, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (122677827..122692763, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene Nanog 5' regulatory region Neighboring gene predicted pseudogene 10224 Neighboring gene Nanog homeobox Neighboring gene Nanog +60 enhancer Neighboring gene uridine-cytidine kinase 1 pseudogene Neighboring gene forkhead box J2 Neighboring gene microRNA 7231 Neighboring gene complement component 3a receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the Slc2a3 gene: The Slc2a3 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by MGI

Function Evidence Code Pubs
D-glucose transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
D-glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
dehydroascorbic acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
dehydroascorbic acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
galactoside binding ISO
Inferred from Sequence Orthology
more info
 
glucose binding ISO
Inferred from Sequence Orthology
more info
 
glucose transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
kinase binding ISO
Inferred from Sequence Orthology
more info
 
monosaccharide transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
xylose binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
carbohydrate transport IEA
Inferred from Electronic Annotation
more info
 
dehydroascorbic acid transport IDA
Inferred from Direct Assay
more info
PubMed 
glucose import across plasma membrane ISO
Inferred from Sequence Orthology
more info
 
glucose transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
glucose transmembrane transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
acrosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
caveola ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of synaptic membrane ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 
synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
solute carrier family 2, facilitated glucose transporter member 3
Names
glucose transporter type 3, brain

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011401.4NP_035531.3  solute carrier family 2, facilitated glucose transporter member 3

    See identical proteins and their annotated locations for NP_035531.3

    Status: VALIDATED

    Source sequence(s)
    AK045328, AK164286, BC053911, BQ769655
    Consensus CDS
    CCDS20502.1
    UniProtKB/Swiss-Prot
    P32037
    UniProtKB/TrEMBL
    Q3TPL8, Q8BLF7
    Related
    ENSMUSP00000032476.4, ENSMUST00000032476.10
    Conserved Domains (2) summary
    cd06174
    Location:14437
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:13465
    Sugar_tr; Sugar (and other) transporter

RefSeqs of Annotated Genomes: Mus musculus Updated Annotation Release 108.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p6 C57BL/6J

    Range
    122727809..122802363 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505822.4XP_006505885.1  solute carrier family 2, facilitated glucose transporter member 3 isoform X1

    See identical proteins and their annotated locations for XP_006505885.1

    Conserved Domains (2) summary
    cd06174
    Location:16439
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:15467
    Sugar_tr; Sugar (and other) transporter
  2. XM_011241268.3XP_011239570.1  solute carrier family 2, facilitated glucose transporter member 3 isoform X1

    See identical proteins and their annotated locations for XP_011239570.1

    Conserved Domains (2) summary
    cd06174
    Location:16439
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:15467
    Sugar_tr; Sugar (and other) transporter
  3. XM_006505823.4XP_006505886.1  solute carrier family 2, facilitated glucose transporter member 3 isoform X1

    See identical proteins and their annotated locations for XP_006505886.1

    Conserved Domains (2) summary
    cd06174
    Location:16439
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:15467
    Sugar_tr; Sugar (and other) transporter
  4. XM_030255284.1XP_030111144.1  solute carrier family 2, facilitated glucose transporter member 3 isoform X1

  5. XM_030255285.1XP_030111145.1  solute carrier family 2, facilitated glucose transporter member 3 isoform X2

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